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Excited state properties of the chromophore of the asFP595 chromoprotein: 2D and 3D theoretical analyses

The ground and excited state properties (e.g., the intramolecular charge and energy transfer, and electron-hole coherence) of the chromophore of the asFP595 chromoprotein from Anemonia sulcata in the neutral and anionic forms are theoretically studied with quantum chemistry methods. The ground-state properties of the asFP595 in the neutral and anionic forms, such as the alternations of the bond le

Diffractive deep-inelastic scattering with a leading proton at HERA

The cross section for the diffractive deep-inelastic scattering process ep -> eX(P) is measured, with the leading final state proton detected in the H1 Forward Proton Spectrometer. The data analysed cover the range x(P) < 0.1 in fractional proton longitudinal momentum loss, 0.08 < vertical bar t vertical bar < 0.5 GeV-2 in squared four-momentum transfer at the proton vertex, 2 < Q(2) < 50 GeV2 in

Diffuse large B-cell lymphoma - tumour characteristics on RNA and protein level associated with prognosis

Popular Abstract in Swedish Diffust storcelligt B-celllymfom (DLBCL) är den vanligaste aggressiva lymfomsjukdomen, och drabbar ca 450 personer årligen i Sverige. Med modern antracyklin-innehållande cytostatikabehandling är DLBCL en potentiellt botbar sjukdom. Av patienter med lokaliserad sjukdom botas 70 %, med spridd sjukdom ca 50 %. Bakgrunden till arbete 1 i denna avhandling var en rapport därDiffuse large B-cell lymphoma (DLBCL) is the most frequent lymphoma subtype. In Sweden 450 new cases are diagnosed annually. With modern anthracycline-containing chemotherapy DLBCL is potentially curable, with an estimated overall cure rate of approximately 50% for patients with advanced stage disease. Through molecular profiling of DLBCL the ?cell-of-origin concept? has been established: patients

The stellar populations of the M31 halo substructure

We present the first results from our survey of stellar substructure in the outskirts of M31 using the Advanced Camera for Surveys on board the Hubble Space Telescope. We discuss the stellar populations associated with five prominent stellar overdensities discovered during the course of our panoramic ground-based imaging survey with the Isaac Newton Telescope Wide-Field Camera; a sixth pointing ta

Determination of NO adsorption sites on Pd(100) using core level photoemission and low energy electron diffraction

The adsorption of NO on Pd(1 0 0) is investigated with high resolution core level spectroscopy and low energy electron diffraction (LEED). Several ordered NO overlayers were observed, in agreement with earlier Studies. Our data clearly show that NO adsorbs in fourfold hollow sites at coverages tip to 0.25 -0.30 monolayer (ML) whereas at 0.5 ML only bridge sites are occupied. By a reinterpretation

Systematic Synthesis of Substituted Phosphido-bridged Osmium Clusters

The labilised clusters [Os3(CO)11–nLn(NCMe)][n= 1, L = PMe3 or CNBut; n= 2, L = P(OMe)3] have been prepared. The reaction of [Os3(CO)11 –nLn(NCMe)] or [Os3(CO)10{P(OMe)3}(NCMe)] with either [Os3(CO)11(PH3)] or [Os3(µ-H)(CO)10(µ-PH2)] led to the formation of the phosphide-bridged clusters [Os6(µ-H)(CO)21{P(OMe)3}(µ-PH2)], [Os6(µ-H)(CO)21(PMe3)(µ-PH2)], [Os6(µ-H)(CO)21(CNBut)(µ-PH2)], [Os6(µ-H)(CO)2

Structure and mobility in water plasticized poly(ethylene oxide)

The change in structure and mobility of poly(ethylene oxide) (PEO) containing 2 wt% of fumed silica and the water self-diffusion coefficient in concentrated PEO-water systems have been investigated at room temperature in the water weight fraction, w(w) range 0-0.50 w/w. Pulsed field gradient nuclear magnetic resonance was used to measure the self-diffusion coefficients. Structure and mobility prop

Graft polymerization of acrylic acid onto macroporous polyacrylamide gel (cryogel) initiated by potassium diperiodatocuprate

Potassium diperiodatocuprate-initiated graft polymerization was found to be an efficient and convenient method for grafting of acrylic acid (AAc) onto superporous polyacrylamide gels, so called cryogels (pAAm cryogels). It was possible to achieve grafting degrees as high as 70% with about 25% yield of grafted polymer with respect to the initial amount of monomer. The superporous structure of the c

Predicting spontaneous termination of atrial fibrillation using the surface ECG

By recognizing and characterizing conditions under which atrial fibrillation (AF) is likely to terminate spontaneously or be sustained, improved treatment of sustained AF may result and unnecessary treatment of self-terminating AF avoided. Time-frequency measures that characterize AF, such as fibrillatory frequency, amplitude, and waveform shape (exponential decay), are extracted from the residual

Ambiguities Thereafter - An Interpretive Approach to Acquisitions

Popular Abstract in Swedish Avhandlingen beskriver och analyserar hur människor som arbetar i ett företag som blir uppköpt upplever uppköpsprocessen. Författaren lyfter fram de många olika tolkningar och upplevelser som finns av uppköpet istället för att ge en homogen återgivning. Författaren hävdar att för att kunna förstå vad som händer i ett företag under en uppköpsprocess så måste man beakta dWhile the human side of mergers and acquisitions is increasingly focused in both research and practice, it still suffers from several forms of oversimplifications. This study addresses the problem of how various employees interpret objectives, corporate identity and other meanings associated with the post-acquisition process, and what roles these multiple interpretations play during this critical

Modeling the increase of nodularin content in Baltic Sea Nodularia spumigena during stationary phase in phosphorus-limited batch cultures

Nodularin (Nod), produced by the brackish/marine cyanobacterium Nodularia spumigena, is a potent hepatotoxin, tumor promoter and is possibly carcinogenic to mammals. It is structurally and toxicologically related to the microcystins, produced by Microcystis aeruginosa in fresh water. A better understanding of the kinetics of Nod production might provide an insight into the physiological and ecolog

Electron microscopy of some molybdenum oxide phases after use as catalysts in oxidative ammonolysis and ammoxidation of toluene

Five molybdenum oxide samples, subjected to conditions of oxidative ammonolysis and ammoxidation of toluene at 450 and 460°C, respectively, have been characterized using X-ray diffraction, scanning and transmission electron microscopy, and specific surface area measurements. In oxidative ammonolysis, the relatively large, freshly prepared MoO3 crystals are reduced to smaller MoO2 crystals with a c

Amino acid substitutions in the N-terminal segment of cystatin C create selective inhibitors of lysosomal cysteine proteinases

We used site-directed mutagenesis to alter the specificity of human cystatin C, an inhibitor with a broad reactivity against cysteine proteinases. Nine cystatin C variants containing amino acid substitutions in the N-terminal (L9W, V10W, V10F and V10R) and/or the C-terminal (W106G) enzyme-binding regions were designed and produced in Escherichia coli. It was discovered that the inhibition profile

Remote Sensing of Forest Decline in the Czech Republic

Popular Abstract in Swedish Avhandlingen beskriver hur man med elektromagnetisk reflekterar strålning, registrerad från satelliter vilka cirkulerar runt jorden kan lokalisera och kvantifiera skador på barrskog i Tjeckien. Signifikanta samband mellan reflektans och barrförluster gör det mögligt att utföra översiktliga uppskattningar av dessa varrförluster med satellitdata. Genom att jämföra skogsThis thesis describes the localisation and quantification of deforestation and forest damage in Norway spruce forests in northern Czech Republic using Landsat data. Severe defoliation increases the spectral reflectance in all wavelength bands, especially in the mid infrared region. These spectral differences allow the separation of three damage categories with an accuracy of 75% using TM data and

Is bone mineral density advantage maintained long-term in previous weight lifters?

This cross-sectional study was done in order to ascertain whether there is a lifelong beneficial effect on bone mineral density (BMD) of early, long-lasting, and intense physical exercise. Forty-eight male ex-weight lifters, mean age 64 years (range 50-79) participated. They had followed a training program of an average of 10 hours/week (range 4-20) for an average of 13 years (range 1-34). They ha

Changes in the concentrations of major, minor and rare-earth elements during leaf senescence and decomposition in a Fagus sylvatica forest

The principal fate during litter decomposition and mineralization is rather well established only for a limited number of elements, mainly essential plant nutrients and a few potentially very toxic metals. Elements which occupy the majority of the positions in the periodical system seems almost unknown in this context. The objectives were, therefore to assess differences in the behavior of 58 mine

Modeling Carbon and Water Fluxes in European Terrestrial Ecosystems

The controlling mechanisms and feedbacks between climate, the carbon and water cycling and vegetation in European ecosystems have attracted much attention in recent years but they are still not sufficiently understood. A better understanding of them is necessary to predict how they will be affected by climate change. Process-based models of ecosystem structure and functioning provide a tool to s

Probabilistic estimation of microarray data reliability and underlying gene expression

Background: The availability of high throughput methods for measurement of mRNA concentrations makes the reliability of conclusions drawn from the data and global quality control of samples and hybridization important issues. We address these issues by an information theoretic approach, applied to discretized expression values in replicated gene expression data. Results: Our approach yields a quan

The pursuit of heavy elements in the HgMn-type star Chi Lupi: Observations with the GHRS in the COSTAR ERA

Observations of the ultra-sharp-lined HgMn star chi Lupi made with the Goddard High Resolution Spectrograph after the Hubble Space Telescope First Servicing Mission display the effect of COSTAR corrective optics upon the spectral resolution of several observing modes. The resolution is restored to levels expected in the absence of the telescope spherical aberration for all observations made throug

Capsular distance in the hip of the healthy child - normal values with sonography and MR imaging.

PURPOSE: To determine the normal values of the anterior and posterior capsular distances of the hip joint in healthy children by means of US, using MR imaging as reference, and to evaluate any possible correlation between age, length, weight and anterior capsular distance (ACD). MATERIAL AND METHODS: In our first study both hips in 14 healthy children (5-18 years old) were examined with US and MR