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A Validation of the Swedish Colorectal Cancer Register – With Focus on Histopathology, Complications and Recurrences

Background: There is an urgent need to evaluate the quality of healthcare systems to improve and deliver high-quality care. Clinical registries have become important platforms for performance measurements, improvements, and clinical research. Hence, the quality of data in registries is crucial. This study aimed to assess the validity of data in the Swedish Colorectal Cancer Register (SCRCR). Metho

The impact of temperature and precipitation on all-infectious-, bacterial-, and viral-diarrheal disease in Taiwan

BACKGROUND: The ongoing climate change will elevate the incidence of diarrheal in 2030-2050 in Asia, including Taiwan. This study investigated associations between meteorological factors (temperature, precipitation) and burden of age-cause-specific diarrheal diseases in six regions of Taiwan using 13 years of (2004-2016) population-based data.METHODS: Weekly cause-specific diarrheal and meteorolog

Stories of paediatric palliative care : a qualitative study exploring health care professionals’ understanding of the concept

Background: By sharing patient stories, health care professionals (HCPs) may communicate their attitudes, values and beliefs about caring and treatment. Previous qualitative research has shown that HCPs usually associate paediatric palliative care (PPC) with death or dying and that they find the concept challenging to understand and difficult to implement. Attending to HCPs’ stories may provide a

Comparison of Grand Canonical and Conventional Molecular Dynamics Simulation Methods for Protein-Bound Water Networks

Water molecules play important roles in all biochemical processes. Therefore, it is of key importance to obtain information of the structure, dynamics, and thermodynamics of water molecules around proteins. Numerous computational methods have been suggested with this aim. In this study, we compare the performance of conventional and grand-canonical Monte Carlo (GCMC) molecular dynamics (MD) simula

Rate-Ratio Asymptotic Analysis of Strained Premixed Laminar Methane Flame Under Nonadiabatic Conditions

Motivated by the pioneering activation-energy asymptotic analysis of strained laminar premixed flames in counterflow by Libby and his coworkers, a rate-ratio asymptotic analysis is carried out to elucidate the structure and predict the critical conditions of extinction of strained premixed methane flames. Steady, axisymmetric, laminar flow of two counterflowing streams: a reactive mixture stream a

Lone threats: a register-based study of Swedish lone actors

This study investigates 30 lone actors in Sweden with a register-based design using a group of male lone actors and two reference groups: same-sex siblings and other male violent extremists. We compare lone actors to the reference groups along social background, criminal background, and co-offending relations (1995 –2016), and mental health (1980–2016). Our results show that lone actors are primar

Computer Vision for Automated Traffic Safety Assessment : A Machine Learning Approach

Traffic safety is a complex and important research area with the potential to save many lives in the future. Two key problems are considered, namely the gathering of reliable and detailed road user statistics which can be used to estimate the safety of a traffic environment and taking advantage of surveillance infrastructure to guide and assist vehicles in real time, primarily autonomous ones. A c

Outcomes of trabecular metal total ankle replacement : a longitudinal observational cohort study of 239 consecutive cases from the Swedish Ankle Registry

Background and purpose — Information on outcomes after some modern total ankle replacement (TAR) designs is scarce. We therefore examined outcomes after trabecular metal (TM) TAR in Sweden by use of data from the national registry. Patients and methods — On December 31, 2020, 239 primary TM TARs had been reported to the Swedish Ankle Registry. We analyzed prosthesis survival probability, using exc

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Sufficiency has long been marginalized in the public and political sustainability discourse. Since attempts to reduce CO2 emissions in the long term have so far fallen short of expectations, sufficiency has recently approached the forefront of scientific and social debates about a »good life«. In addition to a strict reduction target, the sufficiency strategy promises psychological well-being and

A new plastic scintillation resin for single-step separation, concentration and measurement of technetium-99

Technetium is a synthetic element with no stable isotopes, produced as waste in nuclear power plants and in cyclotrons used for nuclear medicine. The element has high mobility, in the form of TcO4 −; its determination is therefore important for environmental protection. Technetium is found in low concentrations and therefore common methods for its analysis include long treatments in several steps

Large Eddy Simulation of the fuel transport and mixing process in a scramjet combustor with rearwall-expansion cavity

Large Eddy Simulation (LES) was employed to investigate the fuel/oxidizer mixing process in an ethylene fueled scramjet combustor with a rearwall-expansion cavity. The numerical solver was first validated for an experimental flow, the DLR strut-based scramjet combustor case. Shock wave structures and wall-pressure distribution from the numerical simulations were compared with experimental data and

SPINART study : validation of the extended magnetic resonance imaging scale for evaluation of joint status in adult patients with severe haemophilia A using baseline data

Introduction: Most previous joint imaging scales for haemophilia have focused on earlier disease stages observed in younger patients. Aim: We sought to demonstrate that the 45-item extended magnetic resonance imaging (eMRI) scale is a valid instrument for measuring joint status in adults with severe haemophilia A. Methods: Six scale categories (effusion/haemarthrosis, synovial hypertrophy, hemosid

Neutron guide shielding for the BIFROST spectrometer at ESS

We report on the study of fast-neutron background for the BIFROST spectrometer at ESS. We investigate the effect of background radiation induced by the interaction of fast neutrons from the source with the material of the neutron guide and devise a reasonable fast, thermal/cold neutron shielding solution for the current guide geometry using McStas and MCNPX. We investigate the effectiveness of the

Transition strengths and band terminations in Zr-86

High angular momentum states in Zr-86 were populated through the Ni-58(S-32,4p) reaction at 135 MeV using the 88-In. Cyclotron at Lawrence Berkeley National Laboratory. Recoiling Zr-86 nuclei were stopped in a thick Ta backing. Prompt multi-gamma coincidences with evaporated charged particles were detected using the full array of GAMMASPHERE and the MICROBALL. Mean lifetimes of 36 levels in Zr-86

A national approach for automated collection of standardized and population-based radiation therapy data in Sweden

Purpose To develop an infrastructure for structured and automated collection of interoperable radiation therapy (RT) data into a national clinical quality registry. Materials and methods The present study was initiated in 2012 with the participation of seven of the 15 hospital departments delivering RT in Sweden. A national RT nomenclature and a database for structured unified storage of RT data a

Bacterial and fungal communities in tracheal aspirates of intubated COVID-19 patients : a pilot study

Co-infections with bacterial or fungal pathogens could be associated with severity and outcome of disease in COVID-19 patients. We, therefore, used a 16S and ITS-based sequencing approach to assess the biomass and composition of the bacterial and fungal communities in endotracheal aspirates of intubated COVID-19 patients. Our method combines information on bacterial and fungal biomass with communi

LACK OF AUTOFLUORESCENCE IN FUNDUS ALBIPUNCTATUS ASSOCIATED WITH MUTATIONS IN RDH5.

PURPOSE:: The purpose of this study was to characterize the phenotype of fundus albipunctatus associated with RDH5 mutations. METHODS:: Four unrelated patients (patients 1-4) aged 35, 32, 19, and 8 years were examined with full-field electroretinography, multifocal electroretinography, optical coherence tomography, and fundus autofluorescence photography. Molecular genetic investigations included

Person-centred, community-oriented, and diversity sensitive primary care for migrants; a EFPC position paper

Aim: This paper aims to describe what constitutes good-quality, accessible, affordable and acceptable primary care for migrants. This includes identifying system adaptations and offering evidence- and practice-based recommendations and guidance for primary care organizations and professionals on how to deliver such care.Background: Migration has significantly diversified European populations. Migr