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A model for the drug release from a polymer matrix tablet - effects of swelling and dissolution

A model for simulating the drug release from a swelling and dissolving polymer tablet is presented and verified to data. The model is based on a mechanistic approach, and it can therefore be employed to study the sensitivity of true physical constants, for instance the drug diffusion coefficient or the drug solubility. The model generates the drug and polymer release profiles and the front positio

Peak flows from thin sedum-moss roof

The runoff from real 3 cm thick sedum-moss roofs and from laboratory roof plots in southern Sweden is measured and analysed. Real rains and artificial storms are used for the analysis. The probability of high runoff is compared with the probability of high precipitation intensity. Intensity-duration-frequency curves for runoff are derived and it is found that the runoff of 1.5 year return period c

Biosensors for Food Analysis: Development and Applications

Reliable analytical methods are increasingly needed in the food and beverage industry for the determination of specific components (e.g. sugars, proteins, vitamins, fats) and for detecting and quantifying chemical contaminants such as pesticides, heavy metals, antibiotics, and pathogenic microorganisms. The need arises from numerous regulatory actions and increased consumer concern about food comp

Complex product form generation in industrial design: A bookshelf based on Voronoi diagrams

Complex product form generation methods have rarely been used within the field of industrial design. The difficulty in their use is mainly linked to constraints – such as functionality, production and cost – that apply to most products. By cou-pling a mathematically described morphology to an optimisation system, it may be possible to generate a complex product form, compliant with engineering and

Perspectives that lay persons with and without health problems show toward coronary heart disease: An integrated biopsychosocial approach.

Objective: We studied what patients with acute coronary heart disease (CHD) considered the three most stressful factors experienced during the month before testing and what they attributed their heart disease to. Methods: We studied the occurrence and severity of physiologic, psychologic, and psychosocial stressors in 117 patients with acute CHD and 117 referents, not diagnosed with CHD, matched b

Fostering Automatic Control Students to Become Innovators

Today, innovation is a key word for many universities, as it constitutes an important part of most universities’ public and scientific outreach task. Many universities are striving to increase the number of innovations generated at the university. A common method is to provide various support for research projects e.g.; providing researchers with information about international patent rights (IPR)

Measurement of the differential cross section for the two-body photodisintegration of He-3 at theta(LAB)=90 degrees using tagged photons in the energy range 14-31 MeV

The two-body photodisintegration of He-3 has been investigated using tagged photons with energies from 14-31 MeV at MAX-lab in Lund, Sweden. The two-body breakup channel was unambiguously identified by the (nonsimultaneous) detection of both protons and deuterons. This approach was made feasible by the overdetermined kinematic situation afforded by the tagged-photon technique. Proton-and deuteron-

Brain Activity in Predictive Sensorimotor Control for Landings: an EEG Pilot Study

Landing from a jump is related to predictive sensorimotor control. Frontal, central and parietal brain areas are known to play a role in this process based on online sensory feedback. This can be measured by EEG. However, there is only limited knowledge about brain activity during predictive preparation for drop landings (DL). The purpose is to demonstrate changes in brain activity in preparation

Clinical Aspects of Screening Detected Celiac Disease among 12-year-olds

Popular Abstract in Swedish Tarmsjukdomen celiaki, glutenintolerans, är en av våra vanligaste kroniska sjukdomar som utvecklas då man inte tål ämnet gluten, ett protein som framför allt finns i vete, råg och korn. För att utveckla celiaki krävs en genetisk sårbarhet, vilket innebär att man i arvsmassan bär på en benägenhet som gör att man kan utveckla sjukdomen vid intag av mat innehållande glutenAbstract Sweden experienced an epidemic (1984-96) of celiac disease in children, partly attributed to changes in infant feed- ing. Our aim was to compare the total prevalence of celiac disease in two birth cohorts of 12-year-olds and relate the findings to each cohort’s ascertained infant feeding. Furthermore, we compared the growth parameters in the children with screening-detected celiac disease

A maximum likelihood estimator of a Markov model for disease activity in Crohn's disease and ulcerative colitis for annually aggregated partial observations.

Crohn's disease (CD) and ulcerative colitis (UC) are chronic inflammatory bowel diseases that have a remitting, relapsing nature. During relapse, they are treated with drugs and surgery. The present study was based on individual data from patients diagnosed with CD or UC at Herlev University Hospital, Copenhagen, Denmark, during 1991 to 1993. The data were aggregated over calendar years; for each

Ultrasound measurements of umbilical cord transverse area in normal pregnancies and pregnancies complicated by diabetes mellitus

Objective: A voluminous umbilical cord has been described in diabetic pregnancies. The aim of this study was to see if measurements of cord diameters might be of value in the evaluation of diabetic pregnancies and especially those suspected of a large for gestational age (LGA) fetus. Methods: In an observational, prospective study umbilical cord areas and vessel diameters were measured between ges

Diagnosis and progression of sacroiliitis in repeated sacroiliac joint computed tomography.

Objective. To assess the clinical utility of repeat sacroiliac joint computed tomography (CT) in sacroiliitis by assessing the proportion of patients changing from normal to pathologic at CT and to which degree there is progression of established sacroiliitis at repeat CT. Methods. In a retrospective analysis of 334 patients (median age 34 years) with symptoms suggestive of inflammatory back pain,

Childhood cancer survivor cohorts in Europe

With the advent of multimodality therapy, the overall five-year survival rate from childhood cancer has improved considerably now exceeding 80% in developed European countries. This growing cohort of survivors, with many years of life ahead of them, has raised the necessity for knowledge concerning the risks of adverse long-term sequelae of the life-saving treatments in order to provide optimal sc

Measurements of light absorption efficiency in InSb nanowires

We report on measurements of the light absorption efficiency of InSb nanowires. The absorbed 70 fs light pulse generates carriers, which equilibrate with the lattice via electron-phonon coupling. The increase in lattice temperature is manifested as a strain that can be measured with X-ray diffraction. The diffracted X-ray signal from the excited sample was measured using a streak camera. The amoun

Metalorganic Chemical Vapor Deposition of Anatase Titanium Dioxide on Si: Modifying the Interface by Pre-Oxidation.

The formation of TiO2 films on clean and pre-oxidized Si(1 1 1) through chemical vapor deposition of titanium(IV) isopropoxide (TTIP) in ultra-high vacuum has been examined by synchrotron radiation photoelectron spectroscopy, X-ray absorption spectroscopy (XAS) and scanning tunneling microscopy. In both cases, TTIP deposition at 500 °C eventually results in an anatase TiO2 film with a carbon-free

The elusive 2s3s S-1 level in BII

It has been known for nearly 30 years that the theoretical and experimental values for the energy of the 2s3s S-1 level in singly ionized boron, B it, differ strongly. Since there is much better agreement for other B II levels, it has been concluded that the experimental value for 2s3s S-1 must be revised. Despite a number of recordings over the years of sliding-spark, hollow cathode and beam-foil