Search results

Bacteria and viruses are threats to human that evolved strategies to bypass the immune system and can cause massive damage. Understanding these strategies and elucidating pathogen interacting partners within the human immune system will pave the way for discovery of new medicines and increase human well-being. Superantigens (SAgs) are toxins that induce a massive immune response, causing sever dis

Objective: To estimate the cost-effectiveness of strategies to prevent spontaneous preterm delivery (PTD) in asymptomatic singleton pregnancies, using prevalence and healthcare cost data from the Swedish healthcare context. Methods: We designed a decision analytic model based on the Swedish CERVIX study to estimate the cost-effectiveness of strategies to prevent spontaneous PTD in asymptomatic wom

Some pesticides, used in large quantities in current European agricultural practices, are suspected of having harmful effects on human health (cancers, metabolic diseases, neurodegenerative diseases). While occupational exposure is now well documented, data on the exposure of the general population to these molecules, mainly through dietary route are lacking. The aim of this work was to identify d

Background Despite well-established guidelines for managing major depressive disorder, its extensive disability burden persists. This Value of Treatment mission from the European Brain Council aimed to elucidate the nature and extent of gaps between best-practice and current-practice care, specifically to: 1. Identify current treatment gaps along the care pathway and determine the extent of these

Internet of Things (IoT) firmware upgrade has turned out to be a challenging task with respect to security. While Over-The-Air (OTA) software upgrade possibility is an essential feature to achieve security, it is also most sensitive to attacks and lots of different firmware upgrade attacks have been presented in the literature. Several security solutions exist to tackle these problems. We observe

Ammonia (NH3) is a promising carbon-free energy carrier. Co-firing of ammonia in solid fuel-fired facilities is a feasible solution to reduce carbon dioxide (CO2) emissions. Solid fuels, such as coal and biomass, contain various trace elements, such as alkali metals and sulfur, which are released to the gas phase during combustion. Experimental characterization and modeling are used to study the p

To survive in the current competitive era, organizations need continuous performance and development. The performance of any organization is linked with their employees’ performance. However, employees give their best when they see subjective career success in the organization. There are certain factors such as work–family enrichment (WFE) that affect employee’s subjective career success. The purp

Two key challenges for governing and managing critical infrastructure risk and resilience are interdependencies between infrastructures and the multi-actor setting in which they operate. This paper looks beyond the Critical Infrastructure (CI) field of research to identify and discuss cross-disciplinary approaches to address these challenges. It explores two related and slightly overlapping resear

The digital transformation is rapidly changing in-store service settings. This paper explores how frontline employees experience and cope with technology-related challenges. Based on a qualitative approach and the use of observations and interviews, this research advances our understanding of how such coping is performed in retail stores and how it contributes to defining employees’ work experienc

The Prophecies is an AI-based chamber opera with interactive features in which the visitors are immersed in a ritualistic and temple-like setting where they can meet a singing oracle who instead of appearing to be connected to ancient divinities receives messages from the digital realm. The underlying theme of the opera is the eternal human search for guidance and our hope for help from external a

BACKGROUND: Centrally inserted central catheters (CICCs) are indispensable in modern healthcare, but unfortunately, come with complications. Catheter-related thrombosis is a well-known complication reported to occur in 5-30% of patients with CICC. There is a paucity of studies that report the incidence of catheter-related thrombosis after the introduction of real-time ultrasound insertion guidance

Background: COVID-19 caused a profound global impact, resulting in significant cases and deaths. The progression of COVID-19 clinical manifestations is influenced by a dysregulated inflammatory response. Early identification of the subclinical progression is crucial for timely intervention and improved patient outcomes. While there are various biomarkers to predict disease severity and outcomes, t

In this thesis, we present and study a few approaches for constructing controllers for uncertain systems, using a combination of classical control theory and modern machine learning methods. The thesis can be divided into two subtopics. The first, which is the focus of the first two papers, is dual control. The second, which is the focus of the third and last paper, is multiple-input multiple-outp

The ecological niche of the recently described limnic microalga Limnomonas gaiensis (Chlamydomonadales) in Northern Europe remains unknown. To decipher the species tolerance capacity to pH, the effects of hydrogen ions on the physiological response of L. gaiensis were investigated. Results showed that L. gaiensis could tolerate exposure from pH 3 up to pH 11, with an optimal survival at pH 5–8. It

With the emergence of Alzheimer's disease (AD) disease-modifying therapies, identifying patients who could benefit from these treatments becomes critical. We evaluated whether a precise blood test could perform as well as established cerebrospinal fluid (CSF) tests in detecting amyloid-β (Aβ) plaques and tau tangles. Plasma %p-tau217 (ratio of phosporylated-tau217 to non-phosphorylated tau) was an

The pathophysiology underlying impaired LV function in PAH remains unclear, with some studies implicating intrinsic myocardial dysfunction and others pointing to LV underfilling. Evaluation of pulmonary vein area (PVA) and flow may offer novel, mechanistic insight by distinguishing elevated LV filling pressure common in myocardial dysfunction from LV underfilling. This study aimed to elucidate LV

A constitutive model for concrete is formulated. Tensile fracture is described using a smeared crack approach where the fracrure energy is considered and the shear stiffneess in the cracked region is gradually reduced as crackling develops. Environmentally induced strain due to variation of moisture and temperature is taken into account and may be made dependent on the stress state. Creep is model

Dan Egonsson, Björn Petersson, and Toni Rønnow-Rasmussen have been instrumental in shaping the Swedish philosophical community over the last thirty years, particularly in the field of ethics. Through their research, teaching, and guidance of the next generation of philosophers, they have made invaluable contributions to the Department of Philosophy at Lund University. This festschrift, which celeb

Digital controllers are traditionally implemented using periodic sampling, computation, and actuation events. As more control systems are implemented to share limited network and CPU bandwidth with other tasks, it is becoming increasingly attractive to use some form of event-based control instead, where precious events are used only when needed. Forms of event-based control have been used in prac