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The aim of this study was to compare inflammatory response and synovial metaplasia in implant-based immediate breast reconstruction with a biological mesh (Veritas®) with that of a synthetic mesh (TIGR® Matrix Surgical Mesh). We hypothesize that the inflammatory response and formation of synovial metaplasia might be different and the rate of capsular contracture therefore different. The patients w

OBJECTIVES:The aim of this study was to apply a previously published method for evaluating radiographic progression, namely, predicted vs. observed radiographic progression in early rheumatoid arthritis (POPeRA), to the Swedish pharmacotherapy (SWEFOT) trial.METHOD:In SWEFOT, 487 patients with eRA were given methotrexate (MTX), and non-responders were randomized to group A [triple therapy: MTX+sul

Focused environmental research projects and continuously operating research infrastructures (RIs) designed for monitoring all subdomains of the Earth system contribute to global observing systems and serve as crucial information sources for environmental scientists in their quest for understanding and interpreting the complex Earth System and contribute to global observing systems. The EU funded E

UppdragArbetet med kunskapssammanställningen definierades av Myndigheten förarbetsmiljökunskap till att omfatta den psykosociala arbetsmiljöns inverkanpå den seniora arbetskraften1 i en svensk kontext, det vill säga effekten påindividen utifrån den mentala arbetsmiljö och den arbetssociala miljö somhen befinner sig i. Dock samvarierar olika faktorer i individers arbetssitua-tion. För att fånga in

Background:The Mediterranean diet (MD) has been proposed as a means for cancer prevention, but little evidence has been accrued regarding its potential to prevent pancreatic cancer. We investigated the association between the adherence to the MD and pancreatic cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.Methods:Over half a million participants

Background: Early diagnosis of mild lymphedema and treatment are important to prevent its progress. The tissue dielectric constant (TDC), measuring local tissue water in the skin and upper subcutis, has neither been related to the water displacement method (WDM) nor been used to diagnose mild arm lymphedema in patients at risk. Our aims were to evaluate TDC and WDM in combination with palpation, e

Background: Lower urinary tract symptoms due to benign prostate enlargement (LUTS/BPE) can lead to significant disturbances to health-related quality of life (HRQoL) and psychological well-being. The aim of this study was to evaluate the effect of pharmacological treatment of LUTS/BPE on disease specific and generic QOL measures. Methods: Evolution was a European prospective, multicenter multi-nat

Introduction: In this study we investigate the risk of radiation-induced serious adverse event of the spine in a large cohort of consecutive retreated patients with palliative radiotherapy (RT) for metastatic cancer in the spine. Methods and materials: From 2010 to 2014, 2387 patients received spinal irradiation with a palliative intent for metastatic spinal cord compression at our institution. T

BACKGROUND: Fragrance mix II (FM II) is included in the baseline patch test series recommended by the International Contact Dermatitis Research Group (ICDRG). Hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC) is the most important sensitizer of the 6 fragrance materials included in FM II. Besides being a part of FM II, HICC is also tested separately in the ICDRG baseline series. OBJECTIVES: The

The behavior of Ethanol and seven fuels in the boiling point range of gasoline but with an Octane Number spanning from 69 to 99 was investigated in Partially Premixed Combustion. A load sweep was performed from 5 to 18 bar gross IMEP at 1300 rpm. The engine used in the experiments was a single cylinder Scania D12. To allow high load operations and achieve sufficient mixing, the compression ratio w

Plastics are widely used in todays society leading to an accelerating amount of plastic waste entering natural ecosystems. Over time these waste products degrade to micro- and, eventually, nanoplastic particles. Therefore, the break-down of plastics may become a critical threat to aquatic ecosystems and several short term studies have demonstrated acute toxicity of nanoplastics on aquatic organism

This dissertation examines people’s understanding of and action according to norms. Two models are distinguished: a cognitive and a non-cognitive model. The cognitive model is characterized by requiring for people to understand norms and each other, and to act accordingly, that they have higher-order mental states whose propositional contents refer to the mental states of others and from these i

Objectives: Long-term, placebo-controlled studies of cholinesterase inhibitors (ChEIs) in Alzheimer’s disease (AD) are not permitted for ethical reasons. Therefore, the advancement of knowledge on longitudinal outcomes in different domains warrants well-designed naturalistic studies. The aim of this study was to explore the 3-year effectiveness of rivastigmine treatment. Methods: The Swedish Alzhe

This thesis concerns the experimental study of mixing and flow characteristic in turbulent circular impinging jets without and with jet orifice manipulators (i.e. passive-fixed perturbations atthe nozzle exit), without and with swirl. The goal of the studies is to understand the basic mechanisms that control the mixing processes in turbulent impinging jets. The applications of such mixing processe

BACKGROUND: Atrial fibrillation (AF) affects about 3.2% of the adult population in the western world and incurs an annual stroke risk of 4.5%. The use of oral anticoagulant (OAC) drugs significantly reduces this risk. OAC drugs seem to be under-utilized, but little is known about why their use is restrained in routine clinical management. The aim of this study was to assess this issue and, from th

Since Solow (Q J Econ 70:65-94, 1956) the economic literature has widely accepted innovation and technological progress as the central drivers of long-term economic growth. From the microeconomic perspective, this has led to the idea that the growth effects on the macroeconomic level should be reflected in greater competitiveness of the firms. Although innovation effort does not always translate i

The aim was to study dentists' judgement on the removal of and on the development of pathology associated with asymptomatic mandibular third molars. Thirty general dental practitioners (GDPs) and 10 oral surgeons were asked to judge 36 molars with equal distribution of three cues: patient's age, angular position and degree of impaction of the molar. Rating on a VAS was found to be an appropriate m