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The pH-dependence of the donor side reactions in Ca2+ -depleted Photosystem II: A role for Ca2+ in the proton expulsion pathway.

Removal of Ca2+ from PSII lead to impaired electron transfer from YZ to P680+ and to inhibition of S state transitions which results in a modified stable S2 state (probed by a stable multiline EPR signal) and the induction of the S2YZox state ("split" signal) by illumination at 0° C. We have performed an EPR study on the pH dependence of these reactions in Ca2+-depleted PSII (prepared by citrate t

Pecularities of heat transfer from in-line tube bundles to upward aqueous foam flow

Four in-line tube bundles with different geometry were investigated for establishing their performance in terms of heat transfer enhancement. Two-phase aqueous foam was used as a coolant. Such coolant was considered, because our previous research showed that large heat transfer intensity may be reached even at small mass flow rate of the foam. Spacing among the centres of the tubes across the firs

Specific Precipitation of Biomolecules Using Synthetic Polymers

Purification is a very important stage in biotechnological processes. The traditionally used precipitation techniques are generally nonspecific and thus one or more chromatographic steps are normally required. There is thus a need for new approaches to improve existing techniques. New, more specific precipitation techniques have been introduced by the use of stimuli-responsive polymers. These poly

Den kvalitetsmärkta högskolan

The Excellent University In just a few years, the quest for quality has become a concern of utmost priority in higher education. Universities, faculties, research councils and the National Agency for Higher Education regularly undertake evaluations to find out whether the academic work performed by university institutions is on “highest international level” or not. Ranking-lists are constantly pu

Design of Fire-exposed Steel Structures - The Swedish Approach

A rational, analytical approach to a fire engineering design of load-bearing steel structures is described. The method of design is directly based on the natural compartment fire concept and on strictly defined functional requirements and performance criteria. The method is permitted to be generally applied in Sweden, as one alternative, since about ten years. For facilitating the practical applic

Brain Tumors: Evaluation of Perfusion Using 3D-FSE-Pseudo-Continuous Arterial Spin Labeling

In this chapter, the advantages and disadvantages of 3D fast spin echo (FSE) pCASL as a measure of brain tumor perfusion are reviewed. In addition, we compare pCASL with other perfusion techniques and discuss future ASL approaches. A prospective study of 28 patients with contrast-enhancing brain tumors was performed at 3 T using dynamic susceptibility contrast (DSC) MRI and pCASL. The visual quali

Changes in phenolic antioxidants during chuno production (traditional Andean freeze and sun-dried potato)

Total antioxidant capacity (TAC), total phenolic compounds (TPH), total flavonoids (TF) and the amounts of individual phenolic compounds were assessed in Bolivian potato cultivars (various Solanum species) before, during and after the traditional freezing and sun-drying of potatoes known as chunos. The TAC of chunos ranged from 0.4 to 2.7 mu mol Trolox equivalents/g dry matter using 2,2'-azino-bis

Quantification of sphingosine 1-phosphate by validated LC-MS/MS method revealing strong correlation with apolipoprotein M in plasma but not in serum due to platelet activation during blood coagulation.

Sphingosine 1-phosphate (S1P) is a signalling sphingolipid affecting multiple cellular functions of vascular and immune systems. It circulates at submicromolar levels bound to HDL-associated apolipoprotein M (apoM) or to albumin. S1P in blood is mainly produced by platelets and erythrocytes, making blood sampling for S1P quantification delicate. Standardisation of sampling is thereby of great impo

Memantine improves attention and episodic memory in Parkinson's disease dementia and dementia with Lewy bodies

ObjectiveIn both dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD), attentional dysfunction is a core clinical feature together with disrupted episodic memory. This study evaluated the cognitive effects of memantine in DLB and PDD using automated tests of attention and episodic memory. MethodsA randomised double-blind, placebo-controlled, 24-week three centre trial of memantin

Subaerial speleothems and deep karst in central Sweden linked to Hirnantian glaciations

The limestones of the upper Katian Boda mud mounds (Ordovician) of the Siljan district in central Sweden are deeply fractured. The fissures were partly synsedimentary and are often lined with stromatolite-like crusts. These crusts thus far are the only known subaerial Ordovician speleothems. They reach depths of up to 30 m below the former mound top. Macroscopically the crusts form decimetre-sized

Benefits and Adverse Events in Younger Versus Older Patients Receiving Neoadjuvant Chemotherapy for Osteosarcoma: Findings From a Meta-Analysis.

PURPOSEThe LIVESTRONG Young Adult Alliance has conducted a meta-analysis of individual patient data from prospective neoadjuvant chemotherapy osteosarcoma studies and registries to examine the relationships of sex, age, and toxicity on survival. PATIENTS AND METHODSSuitable data sets were identified by a survey of published data reported in PubMed. The final pooled data set comprised 4,838 patient

Total plasma protein adducts of allergenic hexahydrophthalic and methylhexahydrophthalic anhydrides as biomarkers of long-term exposure

OBJECTIVES: The aim of this study was to evaluate the applicability of total plasma protein adducts (TPPA) of 2 sensitizing low-molecular-weight allergens, hexahydrophthalic anhydride (HHPA) and methylhexahydrophthalic anhydride (MHHPA), as biomarkers of long-term exposure. METHODS: Urine samples from occupationally exposed workers were analyzed for the levels of urinary metabolites of HHPA and MH

Micturition problems in relation to quality of life in men with prostate cancer or benign prostatic hyperplasia - Comparison with men from the general population

The aim of the study was to investigate men with prostate cancer and benign prostatic hyperplasia (BPH) in comparison with men from the general population in aspects of presence and frequency of micturition problems in remembrance of prior to treatment and currently. Further, the aim was to investigate the impact of micturition problems on quality of life and the association with micturition probl

Pentobarbital modulates gamma-aminobutyric acid-activated single-channel conductance in rat cultured hippocampal neurons

We examined the effect of a range of pentobarbital concentrations on 0.5 microM gamma-aminobutyric acid (GABA)-activated channels (10 +/- 1 pS) in inside-out or outside-out patches from rat cultured hippocampal neurons. The conductance increased from 12 +/- 4 to 62 +/- 9 pS as the pentobarbital concentration was raised from 10 to 500 microM and the data could be fitted by a Hill-type equation. At

Hollow fibre-supported liquid membrane extraction and LC-MS/MS detection for the analysis of heterocyclic amines in urine samples

Heterocyclic amines (HCAs) are potent mutagens/carcinogens to which humans are frequently exposed through the consumption of cooked meat and fish food. The effect of normal intake of HCAs and their role in the aetiology of human cancer is unknown. To some extent, limitations of the existing analytical methods in monitoring the low levels of HCAs in biological samples have hindered obtaining conclu

A general formula for non-cohesive bed load sediment transport

A bed load transport formula for non-cohesive sediment, based on the bed-shear concept of Meyer-Peter and Muller, was developed and validated for steady flows, oscillatory flows, and combined steady and oscillatory flows. The bed load formula introduced in this study was examined using data from experimental and field measurements for a wide range of flows and sediment conditions, as occurring in