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Clinical Outcomes in Percutaneous Coronary Intervention: Studies on Chronic Coronary Syndrome and Drug-Coated Balloons

Background: Percutaneous coronary intervention (PCI) is frequently used in the treatment of chronic coronary syndrome (CCS), although its impact on long-term prognosis and symptom relief remains debated. Among patients undergoing revascularisation with PCI, data on clinical outcomes following drug-coated balloon (DCB) based PCI in unselected patient populations is limited, and the comparative effe

Human Text Query for Sport Data using LLMs

This thesis explores the use of Large Language Models (LLMs) to convert natural language questions into SQL (Structured Query Language) queries within the field of sports analytics, with a focus on a real-world use case for Spiideo, a provider of cloud-based video analysis tools. The study compares different system designs, including single-agent and multi-agent setups, various prompting strategie

Longer scans boost prediction and cut costs in brain-wide association studies

A pervasive dilemma in brain-wide association studies1 (BWAS) is whether to prioritize functional magnetic resonance imaging (fMRI) scan time or sample size. We derive a theoretical model showing that individual-level phenotypic prediction accuracy increases with sample size and total scan duration (sample size × scan time per participant). The model explains empirical prediction accuracies well a

11602.full

pnas201006568 11602..11607 Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors Rohit Sachdevaa, Marie E. Jönssona, Jenny Nelandera, Agnete Kirkebya, Carolina Guibentifa, Bernhard Gentnerb, Luigi Naldinib, Anders Björklunda, Malin Parmara, and Johan Jakobssona,1 aDepartment of Experimental Medical Sciences, Wallenberg Neuroscience Center,

https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/11602.full_.pdf - 2026-05-22

Evaluation of the influence of CO2 on hydrogen production by Caldicellulosiruptor saccharolyticus

Stripping gas is generally used to improve hydrogen yields in fermentations. Since CO2 is relatively easy to separate from hydrogen it could be an interesting stripping gas. However, a higher partial CO2 pressure is accompanied with an increased CO2 uptake in the liquid, where it hydrolyses and induces an increased requirement of NaOH to maintain the pH. This enhances the osmotic pressure in the c

A lysimeter study on the effect of temperature on CO2 emission from cultivated peat soils

A lysimeter method was evaluated for its suitability in gas emission studies by studying the effect of temperature on CO2 emissions (dark respiration) from cultivated peat soils. The study was carried out with organic soils from two locations in Sweden, a typical cultivated fen peat with low pH and high organic matter content (Orke) and a more uncommon fen peat with high pH and low organic matter

Digested wheat gluten inhibits binding between leptin and its receptor

Background: Leptin resistance is considered a primary risk factor for obesity. It has been hypothesized that dietary cereal grain protein could cause leptin resistance by preventing leptin from binding to its receptor. Non-degraded dietary wheat protein has been found in human serum at a mean level of 41 ng/mL. Here, we report our findings from testing whether enzymatically digested gluten from wh

The frequency and prognostic impact of dic(9;20)(p13.2;q11.2) in childhood B-cell precursor acute lymphoblastic leukemia: results from the NOPHO ALL-2000 trial

The dic(9;20)(p13.2;q11.2) is reported to be present in similar to 2% of childhood B-cell precursor acute lymphoblastic leukemia (BCP ALL). However, it easily escapes detection by G-banding analysis and its true prevalence is hence unknown. We performed interphase fluorescence in situ hybridization analyses-in a three-step manner-using probes for: (i) CDKN2A at 9p21, (ii) 20p and 20q subtelomeres

Exosomes from human mesenchymal stem cells conduct aerobic metabolism in term and preterm newborn infants

Exosomes are secreted nanovesicles that are able to transfer RNA and proteins to target cells. The emerging role of mesenchymal stem cell (MSC) exosomes as promoters of aerobic ATP synthesis restoration in damaged cells, prompted us to assess whether they contain an extramitochondrial aerobic respiration capacity. Exosomes were isolated from culture medium of human MSC from umbilical cord of ≥37-w

Growth, feed conversion and faecal discharge of yellowtail kingfish (Seriola lalandi) fed three commercial diets

A study was undertaken to provide data on growth, feed conversion ratio (FCR) and faecal discharge of yellowtail kingfish (Seriola lalandi) fed three commercial diets used previously to culture this species in New Zealand. Fish were raised in tanks from 0.4 to 1.2 kg over the spring (water temperature 14–17°C) and summer (17–22°C) periods. There were considerable differences in volumetric and mass

Modelling of mass and heat transport in dryer fabric structures Part 1. Theoretical model

The dryer fabric influences the mass and heat transfer, separating the hot, moist paper from the ambient drying air. A dynamic model is presented describing this mass and heat transfer in a dryer fabric based on the fabric parameters: effective diffusivity, porosity, tortuosity, calliper, effective permeability, thermal conductivity and basis weight. The model predicts moisture, temperature and pr

Novel Genome-Wide Association Study-Based Candidate Loci for Differentiated Thyroid Cancer Risk

Context: Genome-wide association studies (GWASs) on differentiated thyroid cancer (DTC) have identified robust associations with single nucleotide polymorphisms (SNPs) at 9q22.33 (FOXE1), 14q13.3 (NKX2-1), and 2q35 (DIRC3). Our recently published GWAS suggested additional susceptibility loci specific for the high-incidence Italian population. Objective: The purpose of this study was to identify no

Prospective Study of Human Papillomavirus (HPV) Types, HPV Persistence, and Risk of Squamous Cell Carcinoma of the Cervix

Background: The link between squamous cell cervical carcinoma and human papillomavirus (HPV) 16/18 is well established, but the magnitude of the risk association is uncertain and the importance of other high-risk HPV (HRHPV) types is unclear. Methods: In two prospective nested case-control series among women participating in cytologic screening in Sweden, we collected 2,772 cervical smears from 51

Anti-Nazi 'superstar' or 'racist'? Sture Bolin's politics: continuity, change, and later evaluations

In the spring of 1945, survivors of the Nazi concentration camps arrived in southern Sweden. A project was launched to collect eye-witness accounts of their experiences and document them for posterity. The scholar in charge of this project was Sture Bolin, professor of history at Lund University After his death Erik Lonnroth hailed him as a 'world-famous' historian. By the turn of the century he w

Stochastic Event-Based Control and Estimation

Digital controllers are traditionally implemented using periodic sampling, computation, and actuation events. As more control systems are implemented to share limited network and CPU bandwidth with other tasks, it is becoming increasingly attractive to use some form of event-based control instead, where precious events are used only when needed. Forms of event-based control have been used in prac

Search for metastable heavy charged particles with large ionisation energy loss in pp collisions at root s=8 TeV using the ATLAS experiment

Many extensions of the Standard Model predict the existence of charged heavy long-lived particles, such as R-hadrons or charginos. These particles, if produced at the Large Hadron Collider, should bemoving non-relativistically and are therefore identifiable through the measurement of an anomalously large specific energy loss in the ATLAS pixel detector. Measuring heavy long-lived particles through

Temporal and dietary fat content-dependent islet adaptation to high-fat feeding-induced glucose intolerance in mice.

The high fat-fed mouse is an experimental model for studies of islet dysfunction as a mechanism for glucose intolerance and for evaluation of therapeutic targets. This model is, however, dynamic with a temporal and dietary fat content-dependent impact on islet function and glucose tolerance, the details of which are unknown. This study therefore examined the time course of changes in the insulin r