Search results

A material parameter identification is presented for a fully thermo-mechanically coupled material model based on full field displacement and temperature measurements. The basic theory of the inverse problem is recapitulated, focusing on the choice of the objective function, proposing a new formulation, and explaining in detail the necessary numerical treatment of experimental data during the pre-p

We present the DEAL language for heap assertions that are efficiently evaluated during garbage collection time. DEAL is a rich, declarative, logic-based language whose programs are guaranteed to be executable with good whole-heap locality, i.e., within a single traversal over every live object on the heap and a finite neighborhood around each object. As a result, evaluating DEAL programs incurs ne

Here we present an inverse analyses approach to determining the two-phase moisture transport properties relevant to concrete durability modeling. The purposed moisture transport model was based on a continuum approach with two truly separate equations for the liquid and gas phase being connected by the sorption kinetics. The moisture properties of ten binder-systems containing fly ash, calcined cl

BACKGROUND: Programmed death-ligand 1 (PD-L1) expression on tumor cells is associated with poor prognosis in several malignancies, while partly contradictory and inconclusive results have been presented for colorectal cancer (CRC). This study aimed to evaluate PD-L1 as a prognostic biomarker in CRC by comparing three different antibody clones.METHODS: Patients surgically treated for CRC between Ja

OBJECTIVE: To explore associations of HLA class II genes (HLAII) with the progression of islet autoimmunity from asymptomatic to symptomatic type 1 diabetes (T1D).RESEARCH DESIGN AND METHODS: Next-generation targeted sequencing was used to genotype eight HLAII genes (DQA1, DQB1, DRB1, DRB3, DRB4, DRB5, DPA1, DPB1) in 1,216 participants from the Diabetes Prevention Trial-1 and Randomized Diabetes P

Myocardial infarction is a leading cause of death globally but is notoriously difficult to predict. We aimed to identify biomarkers of an imminent first myocardial infarction and design relevant prediction models. Here, we constructed a new case–cohort consortium of 2,018 persons without prior cardiovascular disease from six European cohorts, among whom 420 developed a first myocardial infarction

At the emergency department (ED), it is important to quickly and accurately determine which patients are likely to have a major adverse cardiac event (MACE). Machine learning (ML) models can be used to aid physicians in detecting MACE, and improving the performance of such models is an active area of research. In this study, we sought to determine if ML models can be improved by including a prior

The acini-islet-acinar (AIA) axis concept justifies the anatomical placement of the Langerhans islets within the exocrine pancreatic parenchyma and explains the existence of the pancreas as a single organ. Amylase has been suggested to play a key role as an anti-incretin factor. Oral glucose tolerance tests (OGTT) were performed on 18 piglets in both a healthy (prior to pancreatic duct ligation (P

Human impacts on the natural world often generate environmental trends that can have detrimental effects on distributions of phenotypic traits. We do not have a good understanding of how deteriorating environments might impact evolutionary trajectories across multiple generations, even though effects of environmental trends are often significant in the statistical quantitative genetic analyses of

The three leading modes of the North Atlantic atmospheric circulation explain about 70% of the winter climate variability. Although climate models generally can capture these modes, biases may induce large uncertainties in regional climate predictions. Here, we evaluate the leading winter modes simulated by CMIP5-PMIP3 and CMIP6-PMIP4 models from the last millennium to future scenarios in comparis

Purpose: Visual functioning evaluated by the Catquest-9SF questionnaire has shown to be a valid measure for assessing a patient's prioritization for cataract surgery. This study adapted Catquest-9SF for visual function outcomes post uni-lateral cataract surgery or bi-lateral cataract surgery. Methods: Visual functioning was assessed before and after uni-lateral or bi-lateral cataract surgery using

Background. The urokinase plasminogen activator (uPA) system is involved in tissue remodelling processes and is up-regulated in many types of malignancies. We investigated whether serum levels of different forms of soluble uPA receptor (suPAR) are associated with survival and in particular with prostate cancer and cardiovascular disease mortality. Methods. Using time-resolved fluorescence immunoas

This article documents the muon reconstruction and identification efficiency obtained by the ATLAS experiment for 139 fb - 1 of pp collision data at s=13 TeV collected between 2015 and 2018 during Run 2 of the LHC. The increased instantaneous luminosity delivered by the LHC over this period required a reoptimisation of the criteria for the identification of prompt muons. Improved and newly develop

In this thesis, we present and study a few approaches for constructing controllers for uncertain systems, using a combination of classical control theory and modern machine learning methods. The thesis can be divided into two subtopics. The first, which is the focus of the first two papers, is dual control. The second, which is the focus of the third and last paper, is multiple-input multiple-outp

For polarization-resolved reflection experiments such as ellipsometry, not only is high reflectivity in a wide spectral range required for mirrors but also the quality of their polarization response is important. Furthermore, for VUV ellipsometry, optimal angles of incidence at the sample are between 45° and 60° with respect to the surface normal. In the best case, a setup should even allow variab

Background: COVID-19 caused a profound global impact, resulting in significant cases and deaths. The progression of COVID-19 clinical manifestations is influenced by a dysregulated inflammatory response. Early identification of the subclinical progression is crucial for timely intervention and improved patient outcomes. While there are various biomarkers to predict disease severity and outcomes, t

Sub-THz deployment is challenging due to high propagation losses, necessitating dense deployment. To reduce cost, RF signal can be distributed via plastic fiber to remote radio units to increase coverage area. In this paper, we propose an antenna-in-package concept for the single-layer substrate on low-cost embedded wafer level ball grid array (eWLB) packages. To suppress the distortion in the bro

This configurative review explores how nurturing and enacting a community-oriented praxis (COP) in teacher education can enhance teacher candidates’ preparedness for teaching roles whilst addressing some broader educational and societal concerns. Here, CoP is defined as practices that consider, connect with, and draw on local community strengths, needs, and aspirations for the good of individuals,