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This study presents 62 years of hindcast wave climate data for the south coast of Sweden from 1959–2021. The 100-km-long coast consists mainly of sandy beaches and eroding bluffs interrupted by headlands and harbours alongshore, making it sensitive to variations in incoming wave direction. A SWAN wave model of the Baltic Sea, extending from the North Sea to the Åland Sea, was calibrated and valida

This dissertation discusses mainly new cryptanalytical results related to issues of securely implementing the next generation of asymmetric cryptography, or Public-Key Cryptography (PKC).PKC, as it has been deployed until today, depends heavily on the integer factorization and the discrete logarithm problems.Unfortunately, it has been well-known since the mid-90s, that these mathematical problems

Reducing the excitation threshold to minimize the Joule heating is critical for the realization of perovskite laser diodes. Although bound excitons are promising for low threshold laser, how to generate them at room temperature for laser applications is still unclear in quasi-2D perovskite-based devices. In this work, via engineering quasi-2D perovskite PEA2(CH3NH3)n-1PbnBr3n+1 microscopic grains

Memristors implemented as resistive random-access memories (RRAMs) owing to their low power consumption, scalability, and speed are promising candidates for in-memory computing and neuromorphic applications. Moreover, a vertical 3D implementation of RRAMs enables high-density crossbar arrays at a minimal footprint. Co-integrated III–V vertical gate-all-around MOSFET selectors in a one-transistor-o

BACKGROUND: Early conduct problems and school failure are prominent risk factors for several adverse outcomes in later life. With the potential of reaching many children at early stages of their life, school-based interventions constitute a valuable approach to universal prevention. Good behavior game (GBG) is a promising school-based behavior management program, having shown immediate reductions

An early and accurate diagnosis of Alzheimer's disease (AD) is required to initiate symptomatic treatment with currently approved drugs and will be of even greater importance if disease modifying compounds in development display a clinical effect. Protein profiles of human cerebrospinal fluid samples from AD patients (n = 95) and population-based healthy controls (n = 72) were analyzed by SELDI-TO

BACKGROUND: Induced hypothermia may be used to reduce metabolism in acute respiratory failure. Hypothermia is accompanied by an increase in pulmonary vascular resistance, as also seen in the early period after lung transplantation. It was our concern that the combination of the two would lead to an increased workload on the right ventricle. METHODS: To test this hypothesis we induced hypothermia t

Aim The controls of gross radiation use efficiency (RUE), the ratio between gross primary productivity (GPP) and the radiation intercepted by terrestrial vegetation, and its spatial and temporal variation are not yet fully understood. Our objectives were to analyse and synthesize the spatial variability of GPP and the spatial and temporal variability of RUE and its climatic controls for a wide ran

Aromatic amino acids play an important role in ultraviolet (UV)-induced photochemical reactions in proteins. In this work, we aim at gaining insight into the photochemical reactions induced by near-UV light excitation of aromatic residues that lead to breakage of disulfide bridges in our model enzyme, Fusarium solani pisi cutinase, a lipolytic enzyme. With this purpose, we acquired transient absor

This thesis consists of four theoretical essays on contingent claim analysis and its connection to Malliavin calculus. The first three papers are analyzed in the famous Black and Scholes model, while the setup of the fourth paper involves an international environment and the presence of exchange rates. In the first essay the tractability of the Malliavin calculus approach to derive the replicatin

A major drawback of the defibration or refining process in manufacturing pulp is that of its large energy requirements. If the mechanics of the process were better understood, large amounts of energy could probably be saved. The initial defibration seems to be crucial for both the quality of the pulp and the total consumption of energy. Numerical simulations by means of the finite element method r

Popular Abstract in Swedish Celler som har förmågan att ge upphov till nästan alla typer av mogna celler i en organism kallas för pluripotenta stamceller. Förutom deras förmåga att bilda olika specialiserade celltyper har pluripotenta stamceller även den unika förmågan att genomgå ett obegränsat antal celldelningar. Under utvecklingen av en organism genomgår pluripotenta stamceller en process somDuring direct cellular reprogramming, forced expression of key transcription factors (TFs) directly converts one terminally differentiated cell type into that of another fate, exemplified in this theses by the conversion of fibroblasts into functional induced neurons (iNs). Direct conversion of mouse fibroblasts to functional neurons was established in 2010, and the starting point of my doctoral

Context Approximately 10% of women with invasive epithelial ovarian cancer (EOC) carry deleterious germline mutations in BRCA1 or BRCA2. A recent article suggested that BRCA2-related EOC was associated with an improved prognosis, but the effect of BRCA1 remains unclear. Objective To characterize the survival of BRCA carriers with EOC compared with noncarriers and to determine whether BRCA1 and BRC

Popular Abstract in Swedish Syftet med sjukgymnastik är att främja hälsa och välbefinnande och hjälpa människor till aktivitet och delaktighet vid sjukdom och skada. Professionen är påverkad av olika hälsoparadigm som hör samman med olika kunskapstraditioner. Det biomedicinska hälsoparadigmet har en dualistisk syn på människan, där normalitet ses som standard, och där syftet är att kurera och korrThe aim of physiotherapy is to promote health and well-being, and to facilitate increased activity and participation of individuals with diseases and injuries. The profession is influenced by different health paradigms which have emerged from different knowledge traditions. The biomedical paradigm of health adopts a dualistic view of mankind in which the normal is regarded as the standard, and the

The Zn-61(30)31 nucleus has been studied via the combined data of two fusion-evaporation reaction experiments using a Ar-36 beam and a Si-28 target foil. The experimental setups involved the Ge array GAMMASPHERE and neutron and charged particle detectors placed around the target position. The resulting level scheme comprises about 120 excited states connected via some 180 gamma-ray transitions. In

The purpose of this study was to investigate the prevalence of toxic agents in attempted and completed suicides. The purpose was also to explore the sources of the drugs taken by suicide attempters. Verbal information on drug intake was collected from 280 suicide attempters during 1987-1990 in the Lund-Orup catchment area. Information on the sources of the drugs was collected from 143 of these att

Objective To compare drug survival on adalimumab, etanercept and infliximab in patients with rheumatoid arthritis (RA). Methods Patients with RA (n=9139; 76% women; mean age 56 years) starting their first tumour necrosis factor (TNF) inhibitor between 2003 and 2011 were identified in the Swedish Biologics Register (ARTIS). Data were collected through 31 December 2011. Drug survival over up to 5 ye

Popular Abstract in Swedish För firande av mässa i den katolska kyrkan krävs ett altare av sten. Altaret ska invigas av en biskop enligt en viss ritual. Ett viktigt element i altarinvigningsritualen är placeringen av reliker i altarets inre. Före reformationen på 1500-talet gällde denna regel även i Norden. Trots altarnas centrala betydelse i den medeltida nordiska kyrkan har de ägnats liten uppmäThis dissertation deals with the subject of altars in the churches of the medieval diocese of Lund. The main work on altars in the Catholic church is Joseph Braun´s Der christliche Altar in seiner geschichtlichen Entwicklung (1924). However, despite its extensive content it does not deal with the conditions in Northern Europe. The general aim of this dissertation is to broaden our knowledge about