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UNLABELLED: Breast, ovarian, and prostate cancers are hormone-related and may have a shared genetic basis, but this has not been investigated systematically by genome-wide association (GWA) studies. Meta-analyses combining the largest GWA meta-analysis data sets for these cancers totaling 112,349 cases and 116,421 controls of European ancestry, all together and in pairs, identified at P < 10(-8) s
Purpose: Current literature emphasizes using a holistic perspective on green packaging development (GPD) as an important strategy for reducing the environmental impact of products’ supply chain (SC). In practice, however, it can be difficult for packaging developers to strike a balance between all the different environmental requirements on packaging, and trade-offs are common. Life cycle assessme
Objectives Workers in the rubber industry are exposed to a complex mixture of hazardous substances and have increased risk of developing several diseases. However, there is no up to date survey examining the exposure in the Swedish rubber industry. One of the toxic compounds in the industry is carbon disulfide (CS2), which is biotransformed to 2-thiothiazolidine- 4carboxylic acid (TTCA). TTCA is u
In daily clinical practice, patients are frequently asked about their swallowing as part of the patient-clinician interview. This study compares the diagnostic performance of a single open question 'What about swallowing?' (usual care) with the Eating Assessment Tool (EAT-10) as reference test in screening for oropharyngeal dysphagia (OD). 303 outpatients at risk of OD were recruited at three univ
Objective: To investigate the potential of acetic acid supplementation as a means of lowering the glycaemic index (GI) of a bread meal, and to evaluate the possible dose - response effect on postprandial glycaemia, insulinaemia and satiety. Subjects and setting: In all, 12 healthy volunteers participated and the tests were performed at Applied Nutrition and Food Chemistry, Lund University, Sweden.
BACKGROUND: Previous studies of associations between diet, obesity, and blood concentrations of alpha-tocopherol and beta-carotene have been equivocal. Furthermore, most studies used only body mass index (BMI) as an obesity measure. OBJECTIVES: Our objectives were to examine the associations between energy and nutrient intakes, alcohol consumption, tobacco use, and serum cholesterol and serum conc
1. The distribution of the carbon monoxide (CO) producing enzymes haem oxygenase (HO)-1 and -2 was studied by immunohistochemistry in the pig's lower urinary tract, including bladder extramural arteries, and the oesophagogastric junction (OGJ). In isolated smooth muscle from the urethra and the OGJ, the mechanisms for CO-induced relaxations were characterized by measurement of cyclic nucleotide le
Popular Abstract in Swedish I många utvecklingsländer i tropiska klimat leder den snabba urbaniseringen till många problem, bl a försämrad termisk komfort i utemiljön. Detta har negativa följder för människors hälsa och välbefinnande och påverkar sociala och kommersiella aktiviteter utomhus negativt. Följaktligen är det mycket viktigt att åstadkomma komfortabla mikroklimat i urban miljö. Den huvuIn many developing tropical countries, rapid urban growth leads to several problems, including increased thermal stress. This has negative consequences for people's health and well-being, and affects social and commercial outdoor activities negatively. Consequently, the creation of thermally comfortable microclimates in urban environments is highly important. The main aim of this thesis is to dee
Popular Abstract in Swedish Teorin för den starka kraften, kvantkromodynamik eller QCD, behandlas här med både perturbativa och icke-perturbativa metoder. Speciellt produktions- och hadroniseringsdynamiken hos tunga partiklar studeras. Dessa partiklar innefattar tunga kvarkar (charm, botten och top), gaugebosoner, leptokvarkar och supersymmetriska partiklar. När tunga långlivade kvarkar (d.v.s. cIn this thesis the phenomenology of Quantum Chromo Dynamics (QCD) is studied in a variety of circumstances from both perturbative and non-perturbative perspectives. The main emphasis is on the production and hadronization of heavy particles, specifically heavy quarks, gauge bosons, leptoquarks and supersymmetric particles. In the hadroproduction of long-lived heavy quarks (i.e. charm and bottom)
During the latest years the research on the effects of moisture on clothing system has been boosted. New information has revealed phenomena, e.g. “heat pipe” effect with its condensation-evaporation cycle(s) that has not been considered earlier in prediction of physiological reactions or evaluating clothing properties. Considering the material properties, e.g. the evaporative resistance measuremen
Carbohydrate-deficient transferrin (CDT) is used as a biomarker of sustained high alcohol consumption. The currently available measurement procedures for CDT are based on various analytical techniques (HPLC, capillary electrophoresis, nephelometry), some differing in the definition of the analyte and using different reference intervals and cut-off values. The Working Group on Standardization of CD
The stress response is governed by automatic neurological and hormonal processes that occur before we become consciously aware of a dangerous situation. If stress ensues for 15-30 seconds, the hormonal processes may have progressed so far that recovery takes an hour or longer instead of minutes. Stress can affect our behavior and in certain professions, such as the police force and emergency servi
Dolphin echolocation clicks measured far off-axis contain two time-separated components. Whether these components overlap and appear as a single signal on axis has received little attention. Here, the scaled reassigned spectrogram analysis was used to examine if bottlenose dolphin (Tursiops truncatus) clicks measured near- or on-axis of the echolocation beam contained overlapping components. Acros
Aims: We aimed to compare two treatment regimes, one with and one without postoperative precautions in hemiarthroplasty patients, in terms of dislocation rate and patient-reported outcome. Direct lateral approach was used. Patients and Methods: 394 patients were included in a cluster-randomized study 2010−2014. Depending on which ward they were admitted to, they were allotted to free rehabilitatio
Evaluation, prioritization and selection of candidate requirements are of tremendous importance and impact for subsequent software development. Effort, time as well as quality constraints have to be taken into account. Typically, different stakeholders have conflicting priorities and the requirements of all these stakeholders have to be balanced in an appropriate way to ensure maximum value of the
