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The relationships between abdominal and pelvic fat compartments and glucose and lipid metabolism were investigated in early postmenopausal women. Fifty-five healthy, postmenopausal women aged 52-53 yr participated in the study. Fat distribution (intra-abdominal and sc abdominal fat, and intrapelvic and sc pelvic fat) was estimated by computed tomography. Insulin sensitivity was assessed by euglyce

A flow injection capacitive biosensor system to detect trace amounts DNA has been developed based on the affinity binding between immobilized histone and DNA. Histones from calf thymus and shrimp were immobilized on gold electrodes covered with self-assembled monolayer (SAM) of thioctic acid. Each of these histones was used to detect DNA from calf thymus, shrimp and Escherichia coli. The studies i

To further understanding of the genetic basis of type 2 diabetes (T2D) susceptibility, we aggregated published meta-analyses of genome-wide association studies (GWAS), including 26,488 cases and 83,964 controls of European, east Asian, south Asian and Mexican and Mexican American ancestry. We observed a significant excess in the directional consistency of T2D risk alleles across ancestry groups, e

This paper discusses five major parameters in desalination, namely technology, raw-water, energy sources, cost and environmental effects. Both size and yield have grown rapidly in desalination plants due to high performance in technology developments in the last few years. Five different types of desalination technology are presented and bench-marked for long-term use: multistage flash evaporation

Natural products have been shown to be an important source of novel compounds for the development of new drugs and pesticides. However, many biologically active natural products contain reactive functionalities that make them toxic. By modifying such reactive compounds chemically it is possible to make use of the reactivity to form novel "natural product-like" compounds and at the same time reduce

Systemic lupus erythematosus (SLE) is an autoimmune disorder with heterogeneous clinical presentation and complex etiology involving the interplay between genetic, epigenetic, environmental and hormonal factors. Many common SNPs identified by genome wide-association studies (GWAS) explain only a small part of the disease heritability suggesting the contribution from rare genetic variants, undetect

The GC content in the third codon position (GC(3)) exhibits a unimodal distribution in many plant and animal genomes. Interestingly, grasses and homeotherm vertebrates exhibit a unique bimodal distribution. High GC(3) was previously found to be associated with variable expression, higher frequency of upstream TATA boxes, and an increase of GC(3) from 5' to 3'. Moreover, GC(3)-rich genes are predom

The streaming instability is a leading candidate mechanism to explain the formation of planetesimals. However, the role of this instability in the driving of turbulence in protoplanetary disks, given its fundamental nature as a linear hydrodynamical instability, has so far not been investigated in detail. We study the turbulence that is induced by the streaming instability as well as its interacti

This research investigated the liquid-phase removal of chloramphenicol (CAP), an emerging contaminant using molecularly imprinted polymers (MIPs). CAP adsorption profiles, equilibrium, and kinetics were analysed. The adsorption performance was compared between MIPs and non-imprinted polymers (NIPs), both with silica or without silica grafting. The imprinting factor (IF) values for the Si@MIPs-CAP

Background: As healthcare becomes increasingly complex, new methods are needed to identify weaknesses in the system that could lead to increased risk. Traditionally, the focus for patient safety is to study incident reports and adverse events, but that starting point has been contested with a new era of safety investigations: the analysis of everyday clinical work, and the resilient healthcare. Th

Decreasing CO2 emissions in the building sector by improving energy efficiency isan essential part of the goal to reduce global CO2 emissions, as the sector accountedfor nearly 40 percent of the energy-related CO2 emissions in 2017.There are six main parameters that affect a building's energy use. These areoutdoor climate, building envelope properties, building services and energysystems, operatio

To achieve a reduced chemical model for comprehensive prediction of ammonia/hydrogen/methane mixture combustion, a detailed chemical mechanism with 128 species and 957 reactions was first assembled using models from literature. Directed relation graph with error propagation (DRGEP) with sensitivity analysis reduction method was then used to obtain compact reaction models. The studied reduction con

Supreme Audit Institutions (SAIs) constitute important democratic institutions, providing citizens with an independent analysis on how the Governmental Offices and the central public administration function. This paper reports on findings from a survey, submitted to all performance auditors at the Swedish SAI, on 3 May, 2011. The response rate was 70 per cent (65 out of 93 respondents). The survey

Sesquiterpene lactone mix detects contact allergy to these compounds present in the plant family Asteraceae. This marker is present in many baseline series. An additional marker is Compositae mix, which is not present in many baseline series. To investigate whether this allergen should be inserted into the Swedish baseline series, sex dermatology centres representing the Swedish Contact Dermatitis

Benefits of implementing Supply Chain Integration (SCI) are acknowledged in existing integration literature. Integration extending beyond functional silos and firm boundaries is expected to provide value for customers in terms of higher quality, improved service level, and reduced costs. In addition, internal integration allows business functions to align around a single company goal. This type of