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The prevalence and incidence of doctor-diagnosed Dupuytren's disease in the general population is unknown. From the healthcare register for Skåne region (population 1.3 million) in southern Sweden, we identified all residents aged 3/420 years (on 31 December 2013), who 1998 to 2013 had consulted a doctor and received the diagnosis Dupuytren's disease (International Classification of Diseases 10th
Background:Due to new legislation in 2011 and 2013, the Swedish public healthcare system has undergone change as regards incident reporting and supervision. Focus has turned to learning from adverse events and sharing this learning with actors within the system. The aim of this study was to explore with what underlying safety ontology adverse events in the incident reporting system are investigate
INTRODUCTION: Studies have shown that adherence to prehospital treatment guidelines, for patients with non-traumatic chest pain is incomplete and that there is a gender difference in treatment provided. PURPOSE: The aim of this study was to examine adherence to guidelines in a nurse-led ambulance system in southern Sweden. METHOD: Retrospective cohort study, including 862 medical records was rev
A fast 2D motion estimator has been developed and evaluated. The method does not utilize block-matching or iterative solutions and is thus more computationally efficient and suitable for real-time motion estimation over the entire image. The method has been evaluated on 1) phantom measurements and 2) in vivo on the carotid artery wall of 17 subjects, where measurements of the longitudinal displace
Ternary isothermal (25°C) polyoxyalkylene triblock block copolymer ((EO)x(PO)y(EO)x where x is the number of ethylene oxide, EO, segments and y is the number of propylene oxide, PO, segments) systems with water and p-xylene as selective solvents for the PEO and PPO blocks, respectively, were chosen as study systems in this thesis as these ternary systems are good model systems for the self-assembl
People with acquired brain injury (ABI) often have problems leading an independent life due to impaired cognitive abilities. One way to address this is to let the patients practise activities of daily living as part of their rehabilitation process. However, some everyday activities can be difficult, inconvenient or risky to practise. The demands of the environment can also have an impact on the in
Finland provides unique opportunities to investigate population and medical genomics because of its adoption of unified national electronic health records, detailed historical and birth records, and serial population bottlenecks. We assembled a comprehensive view of recent population history (≤100 generations), the timespan during which most rare-disease-causing alleles arose, by comparing pairwis
Objectives: Gram-positive, anaerobic cocci (GPAC) can cause infections in humans. Only a few cases of bacteraemia with GPAC have been reported. We describe the clinical and microbiological characteristics of GPAC bacteraemia. Methods: A retrospective population-based study of GPAC bacteraemia 2012–2016 in southern Sweden was performed. GPAC were identified using matrix-associated laser desorption
Patients with both acute and chronic autoimmune thrombocytopenic purpura (AITP) have in vitro lymphocyte defects in the form of platelet-stimulated proliferation and cytokine secretion. A blinded study was performed to determine if these defects are related to serum cytokine levels and/or platelet antigen expression. Compared with controls, 53% of children with chronic AITP, but only 9% of those w
As we look beyond our terrestrial boundary to a multi-planetary future for humankind, it becomes paramount to anticipate the challenges of various human factors on the most likely scenario for this future: permanent human settlement of Mars. Even if technical hurdles are circumvented to provide adequate resources for basic physiological and psychological needs, Homo sapiens will not survive on an
Introduction: Predictive coding models propose that high hypnotic suggestibility confers a predisposition to hallucinate due to an elevated propensity to weight perceptual beliefs (priors) over sensory evidence. Multiple lines of research corroborate this prediction and demonstrate a link between hypnotic suggestibility and proneness to anomalous perceptual states. However, such effects might be m
BACKGROUND: To reduce the costs of maintaining a poliovirus immunization base in low-income areas, we assessed the extent of priming immune responses after the administration of inactivated poliovirus vaccine (IPV).METHODS: We compared the immunogenicity and reactogenicity of a fractional dose of IPV (one fifth of a full dose) administered intradermally with a full dose administered intramuscularl
Sda is a high-frequency carbohydrate histo-blood group antigen, GalNAcβ1-4(NeuAcα2-3)Galβ, implicated in pathogen invasion, cancer, xenotransplantation and transfusion medicine. Complete lack of this glycan epitope results in the Sd(a−) phenotype observed in 4% of individuals who may produce anti-Sda. A candidate gene (B4GALNT2), encoding a Sda-synthesizing β-1,4-N-acetylgalactosaminyltransferase
Cellulose nanocrystal (CNC) incorporation in polymeric matrices is an environmentally friendly approach to mechanical reinforcement. In general, significant mechanical reinforcement can only be achieved by means of good CNC dispersion at random orientation. These primary characteristics are even more relevant for the preparation of nanocomposites based on hydrophobic matrices, such as poly(ε-capro
Microstructure evolution in magnetic materials is typically a non-local effect, in the sense that the behaviour at a material point depends on the magnetostatic energy stored within the demagnetisation field in the entire domain. To account for this, we propose a finite element framework in which the internal state variables parameterising the magnetic and crystallographic microstructure are treat
The discovery of the Higgs boson in 2012, by the ATLAS and CMS experiments, was a success achieved with only a percent of the entire dataset foreseen for the LHC. It opened a landscape of possibilities in the study of Higgs boson properties, Electroweak Symmetry breaking and the Standard Model in general, as well as new avenues in probing new physics beyond the Standard Model. Six years after the
Popular Abstract in Swedish Klumpfot är en medfödd fotfelställning, som drabbar 1 av 1000 barn. Behandlingen består initialt av korrektion av felställningen, genom töjning och eventuellt operation. Det finns flera alternativa metoder att genomföra töjningar, och flera alternativa operationsmetoder. När felställningen korrigerats övergår behandlingen till att bibehålla det uppnådda läget med hjälp Clubfoot is a congenital disorder, affecting about one of 1000 children. Treatment consists of initial correction of the deformity, followed by prolonged orthosis treatment to maintain the correction obtained. There are several different treatment options. Outcome studies, using reliable and valid instruments are rare. In this thesis an assessment instrument, Clubfoot Assessment Protocol (CAP) wa
In this paper, we analyze the potentials of a four-phase 14-GHz CMOS voltage-controlled oscillator, tailored to a sub-harmonic receiver, for signal processing at Ka-band. When mild phase accuracies between in-phase and quadrature down-converted signals are required, the four-phase oscillator displays roughly the same phase noise figure-of-merit as quadrature oscillator counterparts. However, the o
