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The rise in the average temperature of earth has been described as global warming which is mainly attributed to the increasing phenomenon of the greenhouse effect. It is believed that global warming can have several harmful effects on human health, both directly and indirectly. Since malaria is greatly influenced by climatic conditions because of its direct relationship with the mosquito populatio
We identified the gene encoding chondroitin-glucuronate C5-epimerase (EC 5.1.3.19 [EC] ) that converts D-glucuronic acid to L-iduronic acid residues in dermatan sulfate biosynthesis. The enzyme was solubilized from bovine spleen, and an ~43,000-fold purified preparation containing a major 89-kDa candidate component was subjected to mass spectrometry analysis of tryptic peptides. SART2 (squamous ce
Limited responsiveness to inflammatory cytokines is a feature of adult hematopoietic stem cells and contributes to the relative quiescence and durability of the stem cell population in vivo. Here we report that the executioner Caspase, Caspase-3, unexpectedly participates in that process. Mice deficient in Caspase-3 had increased numbers of immunophenotypic long-term repopulating stem cells in ass
The Icelandic highlands are one of the few places left in Europe where tourists can experience pristine wilderness. During the past decades the highlands have, however, witnessed a rapid expansion in natural resource exploitation. This study attempts to evaluate the pristine condition of Icelandic wilderness by testing different methods of identifying and analysing wilderness with respect to natur
OBJECTIVE—Sleep deprivation in healthy men has been experimentally found to result in disturbances in glucose metabolism and in sympathovagal imbalance. The aim of the present study was to investigate whether sleep disturbances and elevated resting heart rate are associated with increased risk of developing diabetes. RESEARCH DESIGN AND METHODS—A group of 6,599 initially healthy, nondiabetic men
Background - The aim of the study was to evaluate the relation between maternal placental Doppler velocimetry, levels of the maternal glucose, and clinical signs of vasculopathy in pregnancy complicated by pregestational diabetes mellitus. Methods and Results - A retrospective study of 155 pregestational diabetic women between the 22nd and 40th weeks of pregnancy, categorized in White classificati
Daniel Cunha misreads us as suggesting that climate change has been a conscious and deliberate strategy of a global elite. This was very clearly not our suggestion. He proposes that the Marxian concept of fetishism is applicable to anthropogenic climate change, apparently unaware of our recurrent use of precisely this concept in a number of publications over the past decades. We thus fundamentally
Every child with severe or moderate haemophilia A or B, born in Sweden during the period 1970-1990, was traced in the national haemophilia register, all 117 case records being surveyed for mode of delivery and perinatal complications. Of the 117 deliveries. 13 were by caesarean section and the remaining 104 vaginal. Of the 13 caesarean sections, 2 were performed because the woman was a haemophilia
Dyslexia is a learning disability characterised by problems with accurate or fluent word recognition, poor decoding, and poor spelling abilities. Although several studies have addressed dyslexia and Web accessibility, less is known about how dyslexia affects information search. This study investigated whether the inclusion of icons in search user interfaces enhances performance among dyslexics. A
Introduction: This work aims to evaluate the possibility to transfer electrical power from a metal plate to the steel-cord within a car tire. If the tire stands on the plate, a connecting surface occurs which can be interpreted as a capacitor, where the rubber compound acts as a dielectric. Method: First the impedance of the tire is evaluated: An analytical model is set-up to describe the system;
The existence of consistent individual differences in behaviour ('animal personality') has been well documented in recent years. However, how such individual variation in behaviour is maintained over evolutionary time is an ongoing conundrum. A well-studied axis of animal personality is individual variation along a bold-shy continuum, where individuals differ consistently in their propensity to ta
Low-density polethylene disks with smooth or course surfaces were implanted in the abdominal wall of rats, and the tissue response was evaluated after 1, 6, or 12 weeks. Cell damage was detected by two different methods. Cells with increased membrane permeability could be identified using fluorescence microscopy by injection of propidium iodide prior to the killing of the rats. Second, cell death
Syftet med detta examensarbete är att undersöka vad som får svenska pensionärer att migrera till Costa del Sol och hur det påverkar deras uppfattning om deras existentiella hälsa som uttryckt i mening-i-livet, sammanhang och tillit. Uppsatsen bygger på ett två veckor långt fältarbete, med observationer, samtal och ett kort frågeformulär. Den övergripande forskningsfrågan är hur migrationen har påvThe purpose of this thesis is to investigate what makes Swedish retirees migrate to Costa del Sol and how it affects their perception of their Existential Health as expressed in Meaning-in-life, Coherence and Trust, building on a two-week fieldwork, with observations, free conversations, and a short questionnaire. The overall research question is how the migration has influenced retiree’s percepti
Can differences in institutional quality explain current account imbalances in the Euro area? This paper emphasizes a link between current accounts and institutional quality based on a country study for Greece. Subsequently it tests the relationship for a homogeneous sample of 24 European countries over the period 1990 through 2013. Regression analysis indicates that institutional quality is cruci
The paper presents the theories of Peter Singer and Tom Regan concerning the moral status of animals and why both deem animals to have a moral standing similar to humans. The two theories differ in their approaches to justifying the moral standing of animals and humans but have very similar conclusions. The paper then goes on to show how both theories have potential problems in justifying that the
Small cell lung carcinoma (SCLC) is an extremely aggressive form of cancer and current treatment protocols are insufficient. SCLC have neuroendocrine characteristics and show phenotypical similarities to the childhood tumor neuroblastoma. As multidrug-resistant neuroblastoma cells are highly sensitive to arsenic trioxide (As2O3) in vitro and in vivo, we here studied the cytotoxic effects of As2O3
Background: A moderate elevation of plasma total homocysteine (tHcy) is considered a potential risk factor for Alzheimer's disease (AD). Methods: We have investigated the main determinants (age, renal impairment, cobalamin/folate status and the presence of vascular disease) of plasma tHcy in 326 patients with AD, and also in 281 patients with mild cognitive impairment (MCI), since about half of th
