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In 1944 Weiss & Taylor presented experimental evidence against "neurotropism" in nerve regeneration. We used a silicone Y-chamber system to repeat some of those experiments. The proximal stump of transected rat sciatic nerve was introduced into the proximal inlet of the Y. One of the distal outlets was left empty, plugged or occupied by a tendon graft, the other outlet being occupied by a nerv
The contribution of this licentiate thesis lies in the modelling of a multi-echelon inventory system with more general backorder cost structures. Backorder costs are traditionally assumed to be linear, whereas we consider structures that are more general functions of the customers’ time in backorder. The system studied is a two-echelon system with one central warehouse and a number of local sites,The contribution of this licentiate thesis lies in the modelling of a multi-echelon inventory system with more general backorder cost structures. Backorder costs are traditionally assumed to be linear, whereas we consider structures that are more general functions of the customers’ time in backorder. The system studied is a two-echelon system with one central warehouse and a number of local sites,
Laser-capture microdissection (LCM) offers a reliable cell population enrichment tool and has been successfully coupled to MS analysis. Despite this, most proteomic studies employ whole tissue lysate (WTL) analysis in the discovery of disease biomarkers and in profiling analyses. Furthermore, the influence of tissue heterogeneity in WTL analysis, nor its impact in biomarker discovery studies have
Current methods for intra-surgical guidance to localize metastases at cancer surgery are based on radioactive tracers that cause logistical challenges. We propose the use of a novel ultrasound-based method, magnetomotive ultrasound (MMUS) imaging that employ a nanoparticle-based contrast agent that also may be used for pre-operative PET/MRI imaging. Since MMUS is radiation free, this eliminates th
Our aim was to explore whether a multi-feature paradigm (Optimum-1) for eliciting mismatch negativity (MMN) would objectively capture difficulties in perceiving small sound contrasts in children with hearing impairment (HI) listening through their hearing aids (HAs) and/or cochlear implants (CIs). Children aged 5–7 years with HAs, CIs and children with normal hearing (NH) were tested in a free-fie
This doctorate thesis focuses on sparse regression, a statistical modeling tool for selecting valuable predictors in underdetermined linear models. By imposing different constraints on the structure of the variable vector in the regression problem, one obtains estimates which have sparse supports, i.e., where only a few of the elements in the response variable have non-zero values. The thesis coll
Effective societal responses to rapid climate change in the Arctic rely on an accurate representation of region-specific ecosystem properties and processes. However, this is limited by the scarcity and patchy distribution of field measurements. Here, we use a comprehensive, geo-referenced database of primary field measurements in 1,840 published studies across the Arctic to identify statistically
Popular Abstract in Swedish Frågan om marknadshandelns karaktär har aktualiserats genom de skandaler inom företagsvärlden som media har lyft fram under senare år. Dagens situation väcker frågor om den handel som förekom i äldre samhällen? Existerade marknadshandel till exempel under vikingatid? Om så var fallet hur uppfattades och hanterades marknadshandel i detta samhälle? Handelns roll för det The view of the exchange and trade that took place during the Viking Age has varied considerably. This variation is obvious from a scrutiny of how one and the same place, Birka, is described by different scholars over a period of a hundred years. Two very polarized pictures of Birka appear: A town with a mostly free market-oriented trade or an emporium with an administered commodity exchange contr
Background How DNA repair enzymes find the relatively rare sites of damage is not known in great detail. Recent experiments and molecular data suggest that individual repair enzymes do not work independently of each other, but interact with each other through charges exchanged along the DNA. A damaged site in the DNA hinders this exchange. The hypothesis is that the charge exchange quickly libera
Curriculum vitae MARTINA ANGELA CARETTA, PHD Birth date : 29th April 1986 Citizenships : Sweden and Italy martina_angela.caretta@keg.lu.se PROFESSIONAL EXPERIENCE January 2021- Senior Lecturer Human Geography Department, Lund University, Sweden August 2016 – December 2020 Assistant Professor of Geography Dept. of Geology and Geography, West Virginia University, USA December 2016 – November 2017 UN
https://www.keg.lu.se/en/sites/keg.lu.se.en/files/2021-08/MartinaA_Caretta_CV_210726.pdf - 2026-05-06
Cancer is the leading cause of death in the world. Multiple different treatment options are available, target therapy and immunotherapy being two. One potential target is Fibroblast Growth Factor Receptors (FGFRs) and there are both available treatments and new treatments being investigated for this. However, only around 25% of patients benefit from the immunotherapy treatment Immune Checkpoint In
Curriculum vitae MARTINA ANGELA CARETTA, PHD Birth date : 29th April 1986 Citizenships : Sweden and Italy martina_angela.caretta@keg.lu.se PROFESSIONAL EXPERIENCE January 2021- Senior Lecturer Human Geography Department, Lund University, Sweden August 2016 – December 2020 Assistant Professor of Geography Dept. of Geology and Geography, West Virginia University, USA December 2016 – November 2017 UN
https://www.keg.lu.se/en/sites/keg.lu.se.en/files/2021-03/MartinaA_Caretta_CV_210308.pdf - 2026-05-06
Course Guide : PX36003 V23 Gerontologi - flervetenskapliga och integrativa perspektiv på åldrandet Course Guide The course Gerontology – Multidisciplinary and Integrative Perspectives on Aging consists of two sub- courses with a total of 5 (3+2) higher education credits (HEC): 1. Perspectives on aging, 3HEC 2. Implementation in own research (optional), 2HEC Please indicate in the Poll whether or n
Background: The Danish Smoking Cessation Database (SCDB) was established in 2001 as the first national healthcare register within the field of health promotion.Aim of the database: The aim of the SCDB is to document and evaluate smoking cessation (SC) interventions to assess and improve their quality. The database was also designed to function as a basis for register-based research projects.Study
Ammonia (NH3) is regarded as one of the most viable alternatives to produce carbon-free energy. However, its low flammability and high NOx emissions associated with its combustion inhibit the implementation of pure NH3 as a fuel. Dual-fuel approaches with NH3 and more reactive fuels have been proposed; however, information on pollutant emissions is still scarce. The present work focuses on quantif
The extracellular matrix protein, tenascin, appears in a restricted pattern during organ morphogenesis. Tenascin accumulates along developing peripheral nerves as they leave the spinal cord and enter the limb mesenchyme (Wehrle and Chiquet, Development 110, 401-415, 1990). Here we found that most but not all tenascin deposited along growing nerves is of glial origin. By in situ hybridization with
BACKGROUND: Semen quality in humans may be influenced by exposure to endocrine-disrupting compounds. OBJECTIVES: We analyzed associations between semen characteristics and serum xenoestrogen receptor (XER), xenoandrogen receptor (XAR), and aryl hydrocarbon receptor (AhR) transactivity. XER and XAR activity were measured in serum samples cleared for endogenous steroid hormones and AhR activity in r
Twelve commercially available triacylglycerol lipase preparations were screened for their suitability as catalysts in the interesterification of palm oil mid fraction and ethyl stearate to form a cocoa butter equivalent. Five fungal lipase preparations were found to be suitable. The hydrolytic activity of the commercial lipase preparations was tested with sunflower seed oil and was independent of
Light-chain (LC) monoclonal gammopathy of undetermined significance (MGUS) is a precursor of multiple myeloma (MM) and related conditions. LC-MGUS is characterized by free light-chain (FLC) levels outside defined reference intervals, indirectly indicating underlying plasma cell (PC) monoclonality. Next-generation flow cytometry (NGF) was used to evaluate clonal PC presence in bone marrow (BM) samp
