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Varför idrottare dopar sig : En intervjustudie om vad som underbygger dopingbruk hos svenska idrottare

I denna studie har elva svenska idrottare som dopat sig intervjuats – tio styrkelyftare och en tyngdlyftare. Idrottarna har varit verksamma på tävlings- till elitnivå, och har fällts för minst en dopingförseelse 1990 till och med 2006. Syftet med studien har varit att identifiera och analysera sociala processer som ligger bakom bruket. Anabola Androgena Steroider (AAS) var det preparat som samtlig

Oxygen therapy in ST-elevationmyocardial infarction

Aims To determine whether supplemental oxygen in patients with ST-elevation myocardial infarction (STEMI) impacts on procedure-related and clinical outcomes. Methods and results The DETermination of the role of Oxygen in suspected Acute Myocardial Infarction (DETO2X-AMI) trial randomized patients with suspected myocardial infarction (MI) to receive oxygen at 6 L/min for 6-12 h or ambient air. In t

Who's the real feminist? : Discursive boundary making in the context of anti-gender campaigns

In recent years, there has been a wave of opposition to feminism, gender equality, and minority rights in various national and international contexts. While there is a growing number of works that examine anti-gender campaigns, less attention has been devoted to the potential consequences of the anti-gender mobilizations for the internal relations within socially progressive (feminist and LGBTQ+) In recent years, there has been a wave of opposition to feminism, gender equality, and minority rights in various national and international contexts. While there is a growing number of works that examine anti-gender campaigns, less attention has been devoted to the potential consequences of the anti-gender mobilizations for the internal relations within socially progressive (feminist and LGBTQ+)

Genomic studies of isolation, diversity loss, and inbreeding in grassland butterflies

Land use change from agricultural intensification has been highlighted as one of the major drivers of global declines in insects, reducing species diversity and abundance and shifting community composition towards generalist species. However, it remains a challenge to determine how land use change impacts the genetic diversity of species and populations even if this diversity is vital to their lon

Mortality in patients with atrial fibrillation and common co-morbidities – a cohort study in primary care

Objective: To study the association between cardiovascular co-morbidities and mortality risk in primary care patients with atrial fibrillation. Methods: The study population included all adults (n = 12,283) ≥ 45 years diagnosed with AF at 75 primary care centres in Sweden between 2001 and 2007. The outcome was mortality (until 2010) and data were explored for co-morbidities using Cox regression wi

Validation of factor VIII activity for monitoring standard and extended half-life products and correlation to thrombin generation assays

Introduction: Monitoring replacement therapy with standard and extended half-life (EHL) products is challenging, since one-stage assay (OSA) and chromogenic substrate assay (CSA) results may differ significantly. Recent recommendations include local validation of each new product with recovery within 20–30%, depending on activity level. Aim: To validate factor VIII (FVIII) activity for monitoring

Block Copolymer Nanolithography for Sub-50 nm Structure Applications

När de kritiska mönsterdimensionerna för högteknologiska enheter fortsätter krympa och mönstertätheten fortsätter öka, behöver även litografin att gå i samma riktning. En lovande teknologi är sampolymerlitografi, som har en upplösning under 10 nm, en mönsterperiodicitet omkring 7-200 nm, och lätt kan skalas upp till större ytor till en låg kostnad. Användandet av sampolymerer där de ingående blockAs high technology device patterns are continuing to move towards decreasing critical dimensions and increasing pattern density, there is a need for lithography to move in the same direction. Block copolymer (BCP) lithography is a promising technique, which has single digit nanometer resolution, has a pattern periodicity of about 7-200 nm, and easily scales up to large area at a low cost. The use

#898 Tumor-informed ctDNA detection as a marker for postoperative residual disease in epithelial ovarian cancer : results of a feasibility study

Introduction/Background Completetumor resection is the most relevant prognostic factor for overall survival in high grade serous ovarian cancer (HGSOC) patients. The current standard for classification of postoperative residual disease is surgeon´s subjective evaluation at the end of surgery. Thus, a reliable objective predictive marker is currently missing.MethodologyIn this prospective single-ce

Artifacts in conventional computed tomography (CT) and free breathing four-dimensional CT induce uncertainty in gross tumor volume determination

Purpose: Artifacts impacting the imaged tumor volume can be seen in conventional three-dimensional CT (3DCT) scans for planning of lung cancer radiotherapy but can be reduced with the use of respiration-correlated imaging, i.e., 4DCT or breathhold CT (BHCT) scans. The aim of this study was to compare delineated gross tumor volume (GTV) sizes in 3DCT, 4DCT, and BHCT scans of patients with lung tumo

Copeptin, a Marker of Vasopressin, Predicts Vascular Dementia but not Alzheimer's Disease

Background: Copeptin is a reliable surrogate marker for the neurohypophyseal hormone vasopressin. Elevated plasma level of copeptin has been associated with cardiovascular and metabolic disease risk. Objective: To investigate the association between copeptin and risk of dementia. Methods: In all, 18,240 individuals from Malmö, Sweden, were examined between 2002 and 2006 (mean age 69.3 years, 69.8

Fishing the gene pool : Genetic structure, admixture and behavioural complexity in fisheries management

Ett fiskbestånd syftar på en grupp artfränder som uppehåller sig inom ett avgränsat område och som huvudsakligen parar sig sinsemellan, vilket medför att de genetiska likheterna är större inom ett bestånd än mellan separata bestånd. Denna beskrivning stämmer väl in på sjölevande fiskarter, där fisk sällan kan röra sig mellan sjöar, vilket alltså leder till genetiska skillnader mellan bestånd i oliPrudent management of marine fish resources relies on separation and management of biologically meaningful groups of conspecifics, termed fishery stocks, often depicted as self-sustaining, spatiotemporally separated and demographically independent entities. Such stock discrimination has however proven challenging. Although most marine fish species form local spawning populations (in relation to hy

Towards sustainable heavy-duty transportation : Combustion and emissions using renewable fuels in a compression ignition engine

Transportation should become sustainable and available to everyone. Currently, transportation accounts for approx. one sixth of greenhouse gas (GHG) emissions globally, and heavy-duty trucks are responsible for almost 30% of that. When fossil diesel fuel is burned in a compression ignition engine, known as a diesel engine, it releases large amounts of CO2, a GHG, into the air. GHGs confine heat in

Guantanamo - ett rättsligt svart hål i kriget mot terrorn? - En utredning kring Bush-administrationens argument för att frånhålla de misstänkta terroristerna krigsfångestatus

President Bush förklarade krig mot terrorn efter att USA blivit utsatta för de värsta terroristattackerna hittills i historien. I den inledande konflikten var al-Qaida och talibanregimen i Afghanistan motståndarna. Flertalet misstänkta terrorister tillfångatogs och transporterades till fånglägret Guantanamo där de hölls utan de rättigheter som de borde ha fått åtnjuta under Genèvekonventionerna soAfter suffering from the worst terror attacks in history, President Bush declares war on terror. In the initial conflict, the al-Qaeda and the Taliban regime constitute the opposition. A number of suspected terrorists are captured and transported to Guantanamo Bay Detention Camp, where they were held captives without the rights that should have been provided by the Geneva Convention as Prisoners o

Vinn mot svinn - En studie som belyser hur producenter kan hjälpa konsumenter att minska sitt omfattande matsvinn

Var tredje inhandlad matkasse slängs, vilket innebär att en tredjedel av all mat har producerats helt i onödan. Detta motsvarar 1,3 miljarder ton varje år - vilket uppskattas kunna mätta tre miljarder hungriga magar. För att uppnå hållbar konsumtion behöver matsvinnet halveras inom tio år. Livsmedelsproduktion skapar utsläpp av växthusgaser, luftföroreningar och bekämpningsmedel som påverkar både Nature has provided us with delicious and nutritious food for many years. It is estimated that one third of all edible food is wasted globally. This means a substantial loss of resources. Consumers are unaware of the great amount of avoidable food waste that is created from household consumption and the environmental impact it has. It is of great importance to increase consumer awareness to reduce

Peace promoting or spurring tension further? How The Indian Express frames Prime Minister Modi´s speeches in regard to identity groups in India

Political leaders affect the ordinary citizen´s perception of the world, making them important to study in relation to the upsurge of tension and conflict. In this specific thesis the focus is on how The Indian Express frames the discourses of the Prime Minister Narendra Modi in India concerning the relationship between Hindus, minorities and Non-Hindus. The analysis is done through an interrelate

Effektivisering av tågvinterunderhåll

-The purpose of this work is to investigate and identify the most efficacious methods to optimize train maintenance and operations during winter months. The study analyzes scheduled and unscheduled maintenance problems during winter months and considers various options on how to streamline current methods and procedures by identifying key areas and addressing optimization. This study presents prop

Hur ser Kristdemokraterna på privatliv? En studie av Kristdemokraternas inlägg i FRA-debatten.

This paper examines the Swedish right-wing party Christian Democrats' (Kristdemokraterna) view on privacy, as expressed in the well known and vibrant FRA-debate. FRA stands for The National Defence Radio Establishment and the debate flourished in 2008-2009, when a new law on the introduction of signals intelligence (SIGINT) was presented by the government in the Swedish parliament. This forced

Rätten till självförsvar

FN-stadgan förhandlades fram, efter andra världskriget, i syfte att minimera risken för framtida krig och ställa all våldsanvändning under FN:s kontroll. Art 2.4 FN-stadgan förbjuder stater att bruka våld och art 51, rätten till självförsvar, är ett undantag från våldsförbudet. Tanken bakom undantaget är att garantera medlemsstaterna rätt till självförsvar om det uppstår en väpnad attack. Syftet

Crowdsource Intelligence – en kvalitativ textanalys av Bellingcats rapportering av MH17

Social media have revolutionized the way we socialize and interact. This has led to an extreme growth in information and a number of new tools has evolved that allows us to exploit data in ways that were previously out of reach for the generalpublic. Lately, we have been able to follow the emergence of various private intelligence initiatives. One of these is Bellingcat. The purpose of this paper