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Spectroscopic differences in posterior insula in patients with chronic temporomandibular pain

Chronic pain including temporomandibular disorder (TMD) pain involves a complex interplay between peripheral and central sensitization, endogenous modulatory pathways, cortical processing and integration and numerous psychological, behavioral and social factors. The aim of this study was to compare spectroscopic patterns of N-Acetyl-aspartate (NAA), total creatine (tCr), choline (Cho), myo-inosito

Rivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial

Background: Patent foramen ovale (PFO) is a contributor to embolic stroke of undetermined source (ESUS). Subgroup analyses from previous studies suggest that anticoagulation could reduce recurrent stroke compared with antiplatelet therapy. We hypothesised that anticoagulant treatment with rivaroxaban, an oral factor Xa inhibitor, would reduce the risk of recurrent ischaemic stroke compared with as

Associations and gastrointestinal symptoms in women with endometriosis in comparison to women with irritable bowel syndrome : a study based on a population cohort

Background: Endometriosis and irritable bowel syndrome (IBS) have similar symptoms, pathogenesis, and risk factors. These diagnoses often coexist and are frequently misdiagnosed leading to diagnostic delays. This study of a population-based cohort aimed to investigate associations relating to endometriosis and IBS and to compare gastrointestinal symptoms between endometriosis and IBS. Method: The

Mäns våld mot kvinnor - ett olösligt samhällsproblem? : Våld i svensk jämställdhetspolitik under 2000-talet

Under snart tre decennier har omfattande insatser genomförts för att få mäns våld mot kvinnor att upphöra, utan synbar effekt. Våldet tenderar snarare att öka. Varför tycks mäns våld mot kvinnor vara ett olösligt samhällsproblem? I denna rapport undersöker vi hur mäns våld mot kvinnor har hanterats i svensk politik de senaste 25 åren. Med utgångspunkt i offentligt tryck granskar vi den politiska r

Normalization of puberty and adult height in girls with Turner syndrome : results of the Swedish Growth Hormone trials initiating transition into adulthood

Objective: To study the impact of GH dose and age at GH start in girls with Turner syndrome (TS), aiming for normal height and age at pubertal onset (PO) and at adult height (AH). However, age at diagnosis will limit treatment possibilities. Methods: National multicenter investigator-initiated studies (TNR 87-052-01 and TNR 88-072) in girls with TS, age 3–16 years at GH start during year 1987–1998

Abnormal cerebral hemodynamics and blood-brain barrier permeability detected with perfusion MRI in systemic lupus erythematosus patients

Objective: Dynamic susceptibility contrast (DSC) magnetic resonance imaging (MRI) has previously shown alterations in cerebral perfusion in patients with systemic lupus erythematosus (SLE). However, the results have been inconsistent, in particular regarding neuropsychiatric (NP) SLE. Thus, we investigated perfusion-based measures in different brain regions in SLE patients with and without NP invo

Incidence of pre-eclampsia : effect of deprivation

Objectives: To examine the relationship between the English index of multiple deprivation (IMD) and the incidence of pre-eclampsia (PE), evaluate the distribution of IMD in a cohort of ethnically diverse pregnant women in South East England and assess whether IMD improves the prediction of PE compared with that provided by the ‘history-only’ competing-risks model (based on maternal characteristics

Chemical composition of the Pulp and Seed Kernels of Baobab fruits from three different African Countries

The baobab is among the commonly consumed wild fruits found in the semi-arid regions of sub-Saharan Africa. It has a wide application in food systems and folk medicine and has an advantage of surviving even in harsh environmental conditions. While the fruit pulp is packed with a lot of essential nutrients and has gained much interest in recent past on the international market as a healthy ‘superfo

Ensam är stark men tillsammans är vi starkare? En teoriprövande studie om kvinnliga parlamentariker

Har kvinnliga ledamöter i Sveriges riksdag någon påverkan på att den politik som förs blir mer fördelaktig för kvinnor i samhället? För att svara på den frågan har vi valt att applicera två teorier, teorin om kritiska massa och representationsteorin, på ändringarna i abortlagstiftningen och resulterande motioner från riksdagens ledamöter. Av de förändringar som skett har tre år varit viktiga för o

Human rights obligations of armed groups exercise control over territory and perform governmental functions

An increasing amount of people living under the control of armed groups begged the question on the human rights obligations by armed groups in situation of protracted armed conflict. Traditionally, international human rights treaties only impose obligations on states. This raises concerns about the protection vacuum as well as accountability of the armed groups. A new phenomenon also emerged where

Investigating CSF flow in patients with idiopathic normal pressure hydrocephalus using phase-contrast 7T MRI

Idiopatisk normaltryckshydrocephalus (iNPH) är en neurologisk sjukdom som påverkar hjärnans vätskecirkulation och kan leda till symtom som gång- och balanssvårigheter, kognitiv nedsättning och urininkontinens. Sjukdomen drabbar omkring 1.5 % av 70-åringar, och prevalensen ökar med åldern. Det är en svårdiagnostiserad sjukdom där hjärnvätska (CSF) ansamlas i hjärnans hålrum, vilket påverkar hjärnanIntroduction: Idiopathic normal pressure hydrocephalus (iNPH) is a treatable but largely underdiagnosed neurological condition affecting the elderly population. It is characterised by gait and cognitive impairment, as well as urinary incontinence. For the most part, it is diagnosed via imaging and clinical assessments. Abnormalities in cerebrospinal (CSF) flow in the cerebral aqueduct have been li

Kan minus bli positivt?

I denna uppsats har en ekonometrisk analys utförts för att undersöka räntans effekt på konsumtionen i Sverige mellan åren 1995-2016. En del av fokusen har legat på de låga räntenivåerna sedan 2009 och den rådande negativa reporäntan. I modellen har även ytterligare makroekonomiska variabler inkluderats för att undersöka vad som har en märkbar effekt på konsumtionen. Enligt resultat har variablernaIn this essay an econometric analysis have been done to investigate and evaluate the steering interest rate effect on consumption in Sweden between the years 1995-2016. Parts of the focus of this essay has been on the low rate levels since 2009, and the current negative rate. In the econometric model, additional macroeconomic variables have been included, in order to investigate what affects consu

Begränsningen av sociala hänsyn vid offentlig upphandling

Public authorities and units are allowed to consider social concerns during public procurements, but have limited room for maneuver. The legal developments during the last 15 years have gone towards more and more freedom for the procurer who wishes to consider social concerns. This makes certain questions regarding pros and cons relevant. The purpose of this paper is to explore these and reason ab

Feasibility of adaptive SBRT of prostate cancer: Investigating uncertainties in AI-driven and CBCT-guided online adaptive radiotherapy

Cancer kan drabba vem som helst och kan ha sitt ursprung i många olika områden i kroppen. Antalet nya cancerfall ökar varje år, men vissa typer av cancer har bättre prognos än andra. Den vanligaste cancertypen i Sverige är prostatacancer och den drabbar framför allt äldre män. Prostatacancer har god prognos och det finns effektiva metoder att helt bota prostat- acancer om den behandlas i ett tidigPurpose: Recent developments in external radiotherapy and its utilization with artificial in- telligence (AI) enables advanced treatment plans for a range of different disease sites. By adapting to the anatomy of the day, target coverage can be ensured while sparing more healthy tissue. The purpose of this project was to study the feasibility and benefits of daily cone beam computed tomography (CB

Application of a dye-binding method for the determination of available lysine in skim milk powders.

A dye-binding method using Acid Orange 12 was investigated regarding its suitability for the quantification of available lysine, as a means of monitoring the Maillard reaction in skim milk powders. The method was evaluated by analyzing a wide range of milk powders produced by three different drying methods and stored under various conditions. A pilot-scale freeze-dryer, spray-dryer and drum-dryer

Psychosocial consequences of false-positive mammography among women attending breast cancer screening. Assessment, prediction, and coping.

Popular Abstract in Swedish Bröstcancer är den vanligaste dödsorsaken bland cancersjuka kvinnor. Därför rekommenderas regelbundna mammografiska hälsokontroller för tidig diagnostik och snar behandling för att förbättra prognosen. I Sverige rekommenderas kontroller för kvinnor mellan 40-74 år. Mammografiska hälsokontroller medför dock även risker, såsom till exempel behov av kompletterande bröstundOne side-effect of breast cancer (BC) screening is a false-positive mammogram among healthy women. That is, finding(s) on a screening mammogram that lead to additional breast examinations but where the woman is eventually considered free from BC. There is evidence of short-term psychosocial consequences of false-positive BC screening. Regarding long-term consequences, research findings are inconsi

Thrombolysis for lower extremity bypass graft occlusion

Background: Thrombolysis is a common method in the treatment of lower extremity bypass graft occlusion. The purpose of this study was to investigate the results of thrombolytic therapy in the management of acute bypass graft occlusion and to identify risk factors for technical failure and amputation. Methods: All patients at two tertiary referral centers undergoing thrombolysis for acute graft occ

Proactive identification of work and situational factors that can affect safety in air traffic control.

In an organization where the safety level is high and incidents and serious accidents are very rare, a steady erosion of safety awareness and protective measures can occur, especially when productive demands rise. Thus, it is important to continuously identify and monitor aspects in the organization that can affect work performance and safety. In an ongoing joint research project between the LFV G