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AIMS/HYPOTHESES: To investigate the effects of extracellular purines on insulin secretion from mouse pancreatic islets. METHODS: Mouse islets and beta cells were isolated and examined with mRNA real-time quantification, cAMP quantification and insulin and glucagon secretion. ATP release was measured in MIN6c4 cells. Insulin and glucagon secretion were measured in vivo after glucose injection. RESU
We investigated the in vivo effects of two novel calcitonin gene-related peptide (CGRP) binding molecules in the genuine closed cranial window model in the rat. The RNA-Spiegelmer (NOX-C89) and the monoclonal CGRP antibody are CGRP scavengers and might be used as an alternative to CGRP-receptor antagonists in the treatment of migraine. Rats were anaesthetized and a closed cranial window establishe
Background: The etiologies of glioma and meningioma tumors are largely unknown. Although reproductive hormones are thought to influence the risk of these tumors, epidemiologic data are not supportive of this hypothesis; however, few cohort studies have published on this topic. We examined the relation between reproductive factors and the risk of glioma and meningioma among women in the European Pr
Abstract in UndeterminedThe recent MPEG Reconfigurable Media Coding (RMC) standard aims at defining media processing specifications (e.g. video codecs) in a form that abstracts from the implementation platform, but at the same time is an appropriate starting point for implementation on specific targets. To this end, the RMC framework has standardized both an asynchronous dataflow model of computat
Phosphorylation of the α-synuclein (α-syn) protein at Ser129 [P(S129)-α-] was found to be the most abundant form in intracellular inclusions in brains from Parkinson's disease (PD) patients. This finding suggests that P(S129)-α-syn plays a central role in the pathogenesis of PD. However, it is at present unclear whether P(S129)-α-syn is pathogenic driving the neurodegenerative process. Rodent stud
Hematopoietic stem cells (HSCs) are ultimately responsible for the all mature blood cell production. They can primarily be found in the bone marrow (BM) at a low frequency (~0.02%). Unlike other blood cells, HSCs have a high degree of self-renewal capacity, the process where upon cell division, at least one daughter cell has the same properties as the stem cell it was generated from. In addition,
Popular Abstract in Swedish Det här arbetet handlar om individuell religiositet, snarare än om religion. Min studie rör i första hand människor som utövar zen, och har mindre att göra med zenbuddhism som ideologiskt system. Jag försöker utforska det stora gapet mellan teori och praktik. De mer abstrakta doktrinerna och idealiserande normerna har haft en benägenhet att dominera arbeten om zen, såväThis work is not so much about religion as about individual religiosity. It is primarily about people practicing Zen, less about Zen Buddhism as a systematic ideology or philosophy. I set out from the start to try to explore the wide gap between theory and practice in Zen. The more abstract doctrines and idealized norms have had a tendency to dominate works on Zen, confessional as well as scholast
Popular Abstract in Swedish Tvärströms mikrofiltrering är en teknik för att avskilja partiklar med en storlek på ungefär en mikrometer (en tusendel av en millimeter) från vätskor. Exempel på tillämpningar är avskiljning av jästceller från öl, och avskiljning av bakterier från mjölk. I mikrofiltrering används membran (filter) med porer med en storlek på 0.1 - 10 mikrometer. Mikrofiltreringsmembran Crossflow microfiltration is a technique to separate suspended particles (or cells or droplets) from liquids by use of a membrane that is permeable for the liquid but impermeable for the particles. The permeate flow drives particles to the membrane surface, where they may be deposited and form a fouling layer. To limit the growth of this fouling layer a flow is applied tangentially to the membrane
The work described in this thesis represents a biophysical approach, mainly using nuclear magnetic resonance (NMR) spectroscopy, to investigate the impact of magnesium ions on the EF-hand calcium-binding proteins calmodulin and calbindin D9k, as well as the dynamics of these proteins at low calcium levels. The x-ray structure of magnesium-saturated calbindin D9k shows a magnesium ion in only one o
Title: What Goes Around Comes Around Seminar date: 15th of January 2021 Course: FEKH49, Business Administration: Bachelor Degree Project in Organization, Undergraduate level, 15 University Credits Points Authors: Frida Briggner, David Mirosavic, Rebecca Tisén, Carolina Wester Advisor: Nadja Sörgärde Keywords: Leadership, Donald Trump, Media, Social constructionism, and Social Contagion Purp
In the manufacturing process of Tetra Pak packages, holes are cut out of the paperboard for straws and caps. The left-over paperboard clippings, called confetti, need to be evacu- ated from the machine. However, this evacuation process has proven to cause problems due to jams arising as the confetti get stuck in joints and along the pipe walls. This study investigates how the confetti behave, defo
Sitting in a high chair gives a feeling of security and of having control - you get an overview of the room you are in. But high chairs are often difficult to get up on, you feel clumsy, there is no good support for your feet and they are often quite uncomfortable. The research I have done shows that many people therefore reject the high chair, despite the positive feelings it can also give. Thos
Climate change as an environmental and social phenomenon exacerbates the increasing ecological strain on Earth. Therefore, a plethora of measures is needed to get onto a more sustainable track towards a low-carbon society. We need to act fast as we are approaching the point of no return. Many strategies to mitigate and stabilise the climate have been developed, one of them being low-carbon initiat
Hur människor rör sig genom staden till vardags spelar roll. Inte minst inom stadsplanering har fysisk mobilitet kommit att bli en viktig fråga, då denna sägs ha potential att motverka segregationsprocesser. Trots detta råder det brist på akademisk forskning inom området. Denna uppsats kombinerar ett intresse för hur mobilitet respektive den vita medelklassen påverkar städers socio-spatiala uppdelPeople’s everyday movements across the urban space matter. Indeed, for city planners looking to counter urban segregation processes, the issue of physical mobility is of prime concern as it bears the potential of overcoming ethnic and socio-economic divisions in the city. Yet, there is a lack of academic research matching this interest. In examining the role of mobility and the white middle-class
Examensarbetets titel: Låga räntor och höga utdelningar - En studie om påverkansfaktorer på svenska fastighetsbolags kapitalstruktur Seminariedatum: 3 juni 2020 Ämne/kurs: FEKH89, Examensarbete i finansiering på kandidatnivå, 15 högskolepoäng. Författare: Fredrik Huitfeldt, Jakob Nilsson och Emelie Persson. Handledare: Göran Andersson. Fem nyckelord: Fastighetsbolag, Kapitalstruktur, PåverkansfaktTitle: Low interest rates and high dividends - A study of influencing factors on Swedish real estate companies' capital structure Seminar date: June 3 2020 Course: FEKH89, Degree Project Undergraduate Level Business Administration, Undergraduate Level, 15 University Credits Points. Authors: Fredrik Huitfeldt, Jakob Nilsson och Emelie Persson. Advisor/s: Göran Andersson. Key words: Real Estate
There is a growing expectation in the field of sustainable development that cities are the most suitable scale for addressing global environmental issues, particularly through their ability to mobilize local actors. Business improvement districts (BIDs) are a form of public-private partnership (PPP) in cities typically established by associations of private actors that aim to generate value in com
Examensarbetets titel: Inköp av företagsbilar – påverkar Inbound Marketing? En kvalitativ studie på Inbound Marketing och dess roll i organisatoriska inköp av företagsbilar hos Din Bil i Malmö Seminariedatum: 2020-01-16 Ämne/kurs: FEKH29 Företagsekonomi: Examensarbete i marknadsföring på kandidatnivå Författare: Alfred Bytyci, Daniel Ostojic, Sasa Veljkovic Handledare: Annette Cerne Nyckelord: InbTitle: Procurement of company cars – does Inbound Marketing affect? A qualitive study of Inbound Marketing and its role in the organizational buying of company cars from Din Bil in Malmö. Seminar date: 2020-01-16 Course: FEKH29 Business Administration: Bachelor Degree Project in Marketing Undergraduate Level Authors: Alfred Bytyci, Daniel Ostojic, Sasa Veljkovic Advisor: Annette Cerne Key words: I
In recent years, digital technologies provided new affordances for movement leaders as communication strategies in political protests in order to advance democratisation processes, especially in less developed countries. In Ethiopia, numerous protests have been taken place lately, which were mainly organised along ethnic lines on the basis of nationalist sentiments. Political activists in Tigray,
Barn har ett särskilt skyddsvärde och när de utsätts för brottsliga gärningar har de, precis som vuxna, ett behov av upprättelse men också en rätt att få uppleva att rättvisa skipas för att få ett avslut på brottsupplevelsen. I Sverige tillmäts den rättsliga hanteringen av unga brottsoffer stor betydelse för utgången i målet och det ställs således höga krav på att barnets särskilda behov tas i beaChildren have a specific need for protection and especially when subject to criminal acts. Similar to adults, children also have a need for redress and a right to experience that justice will be served in order to find a closure to the process associated with crime victimization. In Sweden, the legal treatment of young victims of crime is of great importance for criminal judgement and thus high de
In the midst of a global shift in world politics induced by the rise of emerging powers, the outdated and unequal international financial institutions (IFIs) that were set up after World War II are increasingly being challenged and scrutinized. International actors can use IFIs in numerous ways to enhance their position in the world system. For instance, they can be used as a vehicle to launder st
