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Effect of virtual reality exposure therapy on social participation in people with a psychotic disorder (VRETp) : Study protocol for a randomized controlled trial

Background: Many patients with a psychotic disorder participate poorly in society. When psychotic disorders are in partial remission, feelings of paranoia, delusions of reference, social anxiety and self-stigmatization often remain at diminished severity and may lead to avoidance of places and people. Virtual reality exposure therapy (VRET) is an evidence-based treatment for several anxiety disord

Linguistic relativity in SLA : Towards a new research program

The purpose of the current article is to support the investigation of linguistic relativity in second language acquisition and sketch methodological and theoretical prerequisites toward developing the domain into a full research program. We identify and discuss three theoretical-methodological components that we believe are needed to succeed in this enterprise. First, we highlight the importance o

Atrial Fibrillation and Clonal Hematopoiesis in TET2 and ASXL1

Importance: Clonal hematopoiesis of indeterminate potential (CHIP) may contribute to the risk of atrial fibrillation (AF) through its association with inflammation and cardiac remodeling. Objective: To determine whether CHIP was associated with AF, inflammatory and cardiac biomarkers, and cardiac structural changes. Design, Setting, and Participants: This was a population-based, prospective cohort

The Near East as a cradle of biodiversity : A phylogeography of banded newts (genus Ommatotriton) reveals extensive inter- and intraspecific genetic differentiation

The banded newt (genus Ommatotriton) is widely distributed in the Near East (Anatolia, Caucasus and the Levant) – an understudied region from the perspective of phylogeography. The genus is polytypic, but the number of species included and the phylogenetic relationships between them are not settled. We sequenced two mitochondrial and two nuclear DNA markers throughout the range of Ommatotriton. Fo

Technological Innovation Adoption Among Swedish Healthcare Professionals : A Contingency Technology Adoption Framework

Technological innovation adoption by healthcare professionals directly impacts enhanced patient care and overall community well-being. However, the perspective of healthcare professionals in evaluating and adopting these technological innovations should be addressed. Drawing on innovation adoption and resistance theories, in this article, we aim to capture their perceptions of the barriers they fa

Cropland abandonment in the context of drought, economic restructuring, and migration in northeast Syria

Farmland abandonment is often associated with biophysical, political, or socio-economic changes, like droughts, economic reforms, rural-urban migration, or armed conflicts. Syria has seen several such changes in the period between 2000-2011, however, few assessments of how these factors have interacted with land abandonment have been carried out. In this study we investigate land abandonment patte

Motion event categorisation in a nativised variety of South African English

The present study seeks to expand the current focus on acquisition situations in linguistic relativity research by exploring the effects of nativisation (the process by which a L2 is acquired as a L1) on language-specific cognitive behaviour. Categorisation preferences of goal-oriented motion events were investigated in South African speakers who learnt English as a L1 from caregivers who spoke En

Neighborhood green spaces and use of social services in an older urban population

With an aging population, an increased burden is put on national and regional healthcare and social systems. In Sweden, municipalities are required to provide inhabitants with the social services needed to enable them to live an independent life in their own home for as long as possible. Urban green spaces (UGS) may increase physical activity and social interaction, as well as improve wellbeing an

Infant urinary tract infection in Sweden — A national study of current diagnostic procedures, imaging and treatment

Background: Urinary tract infection (UTI) in infants is a common, potentially life-threatening bacterial infection, and must be managed carefully through the entire chain of care from diagnosis, choice of treatment, follow-up and risk stratification of future complications. This Swedish nationwide study of infant UTI was conducted to evaluate the current management of infant UTI, yield of investig

High prevalence of FAP+ cancer-associated fibroblasts predicts poor outcome in patients with high-grade serous ovarian cancer with high CD8 T-cell density

Objective: Studies have implied that fibroblasts may act as regulators of immune cells in the tumor microenvironment (TME). We investigated the clinical relevance of fibroblast activation protein (FAP) positive stroma in high-grade serous ovarian cancer (HGSC) in relation to CD8+ lymphocyte's infiltration. Methods: In a discovery cohort (N = 113) of HGSC, expression of FAP and CD8 in the TME was a

The association between haemosporidian infection and non-breeding moult location in great reed warblers revisited by combining feather stable isotope profiles and geolocator data

Stable isotope analysis provides valuable insights into the ecology of long-distance migratory birds during periods spent away from a specific study site. In a previous study, Swedish great reed warblers (Acrocephalus arundinaceus) infected with haemosporidian parasites differed in feather isotope ratios compared to non-infected birds, suggesting that infected and non-infected birds spent the non-

Crystallization of sodium sulfate in two-dimensional interconnected pore system : Insights into localized, transient, and anisotropic stress generation and material deterioration

Crystallization-induced stress within confined spaces of porous materials presents significant challenges across various disciplines, including conservation science, geomorphology, geotechnical engineering, and concrete durability. Despite its significance, understanding how localized, transient, and anisotropic stress is generated in pores due to salt crystallization, along with its mechanisms of

Dopaminergic neurons lacking Caspase-3 avoid apoptosis but undergo necrosis after MPTP treatment inducing a Galectin-3-dependent selective microglial phagocytic response

Parkinson’s Disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons in the Substantia nigra pars compacta (SNpc). Apoptosis is thought to play a critical role in the progression of PD, and thus understanding the effects of antiapoptotic strategies is crucial for developing potential therapies. In this study, we developed a unique genetic model to

Asymmetric influence of the amplitude-dependent tune shift on the transverse mode-coupling instability

At the 3 GeV ring of the MAX IV Laboratory, a fourth-generation ring-based synchrotron light source, an asymmetric influence of the sign of the amplitude-dependent tune shift (ADTS) on the transverse mode-coupling instability has been observed. Measurements of the instability, in dedicated single-bunch experiments at low chromaticity, revealed a significant dependence of the dynamics of the instab

Examining senior citizens’ in public transport : The role of digitalization, environmental concern, and traveler satisfaction

Increasing the share of travelers using public transport is one way to address environmental problems such as carbon dioxide emissions. Senior citizens represent an increasingly important group in this transition, as they are increasingly mobile and make up a large share of the population. In this paper, we investigate senior citizen's mobility decision-making, focusing on public transport. Throug

Biological mechanisms of resilience to tau pathology in Alzheimer’s disease

Background: In Alzheimer’s disease (AD), the associations between tau pathology and brain atrophy and cognitive decline are well established, but imperfect. We investigate whether cerebrospinal fluid (CSF) biomarkers of biological processes (vascular, synaptic, and axonal integrity, neuroinflammation, neurotrophic factors) explain the disconnection between tau pathology and brain atrophy (brain re

Entanglement signature in quantum work statistics in the slow-driving regime

In slowly driven classical systems, work is a stochastic quantity and its probability distribution is known to satisfy the work fluctuation-dissipation relation, which states that the mean and variance of the dissipated work are linearly related. Recently, it was shown that generation of quantum coherence in the instantaneous energy eigenbasis leads to a correction to this linear relation in the s

Pre-treatment metastatic biopsy : a step towards precision oncology for urothelial cancer

Early metastatic spread and clonal expansion of individual mutations result in a heterogeneous tumour landscape in metastatic urothelial cancer (mUC). Substantial molecular heterogeneity of common drug targets, such as membranous NECTIN4, FGFR3 mutations, PDL1 or immune phenotypes, has been documented between primary and metastatic tumours. However, translational and clinical studies frequently do