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The aim of this project is to transfer and implement a monoclonal antibody purification process that is traditionally done on an ÄKTAxpress to another machine called the ÄKTA pure. This is due to the fact that the ÄKTAxpress is being discontinued by the manufacturer and a replace-ment machine is needed for the time being. The project will include developing some new meth-ods that might also highli
30 juni 2022 trädde en omfattande ändring av lag (1982:80) om anställ-ningsskydd i kraft. Ändringarna syftade dels till att göra det lättare för ar-betstagare att komma in samt få en trygg anställning på arbetsmarknaden, dels att göra det enklare och mer flexibelt för arbetsgivare att anställa och avsluta anställningar och därmed minska riskerna med att anställa. Bland annat bytte allmän visstidOn June 30, 2022, a comprehensive amendment to the Employment Protec-tion Act (1982:80) came into effect. The changes aimed to make it easier for employees to enter and secure employment in the labor market, as well as to simplify and provide more flexibility for employers in hiring and terminating employment, thereby reducing the risks associated with hiring. Amongst other changes "general f
Syftet med denna kvalitativa studie var att genom halvstrukturerade intervjuer undersöka unga vuxnas erfarenheter av att medicinera mot depression, samt hur de förstår sitt tillstånd som deprimerade. Elva informanter mellan 20 och 30 år, som diagnostiserats med depression och använt SSRI eller SNRI, intervjuades, och materialet analyserades med hjälp av tematisk analys. Resultatet visade att inforThe purpose of this qualitative study was to explore how young adults experience depression and antidepressant medication, and how they understand their condition. Using semi-structured interviews, eleven interviewees between the ages of 20 and 30, who had been diagnosed with depression and had medicated with SSRI or SNRI, were interviewed, and the results were analyzed using thematic analysis. Th
The digital development in society and the new eIDAS regulation which is replacing the current eSignature directive and the Swedish law on electronic signatures through which the directive is implemented, raises the interest for electronic signatures and the possibilities these provide. In this context this essay aims to analyse the functions of electronic signatures and which impact the new regul
The HIE-ISOLDE post accelerator at CERN has recently come online, en- abling the use of radioactive ion beams with energies of up to 10 MeV/u. An active target gaseous detector is under development for use in some of the experiments. The first investigation of the electron amplification stage with gas electron multipliers has been performed. To this end, a small prototype GEM detector was built an
As trade wars commence and European integration deepens it becomes increasingly important to investigate the effects that such actions have on the economy. This thesis investigates the effect that the EU and Eurozone has on the economic growth of its member nations. The study utilizes an augmented Solow-model in a fixed effects framework to see the effect that the EU and Euro has had on economic g
A model is used to describe a system physically or mathematically and to give information about changes in the system variables. Physical knowledge about the system and its quantities can be useful to build a physical model obeying the laws of nature. However, if the system is to be regarded as a black box with only input and output signals, system identification can be used to fit a mathematical
The object of the study is to discuss how methods for increase interaction with communities can contribute to find ways for building relationships between local journalists and publics. Also, the study aims to display how trust can contribute to strategies for social sustainability of local journalism. Exploring new ways of studying communication and interactions in media and journalism is of high interest considering that we live in a constantly transforming media landscape. To build sustainable journalism and media organizations requires a holistic approach of the development involving audience, news producers and other stakeholders.This panel originates from studies applying action research o
Millimeter wave (mm-wave) communication with large-scale antenna array configuration is seen as the key enabler of the next generation communication systems. Accurate knowledge of the mm-wave propagation channels is fundamental and essential. In this contribution, a novel complexity-efficient high resolution parameter estimation (HRPE) algorithm is proposed for the mm-wave channel with large-scale
OBJECTIVE: In light of reports of de novo LN during belimumab (BLM) treatment, we sought to determine its frequency and contributing or protective factors in a real-life setting. METHODS: Patients with SLE who received BLM between 2011 and 2017 at five European academic practices were enrolled (n = 95) and followed longitudinally for a median time of 13.1 months [interquartile range (IQR): 6.0-34.
Popular Abstract in Swedish Blåsexstrofi är en ovanlig och mångfasetterad missbildning. I hela Sverige föds cirka tre barn om året med blåsexstrofi. Bukvägg och urinblåsa är öppna nedanför naveln, så att man ser blåsans insida samt rinnande urin. Flickorna har en delad clitoris, framflyttad och trång slidöppning samt framflyttad ändtarmsöppning. Pojkarna har en kort, öppen penis, som ligger uppfälBladder exstrophy is a complex malformation seen in 1/30 000. Most children are subject to repeated operations, including pelvic osteotomy, genital and bladder neck reconstruction and sometimes bladder augmentation or a urinary reservoir, to achieve continence and a normal genital function. A retrospective study of all Swedish children born 1970-89 showed a low continence rate, 17% , and a high r
BACKGROUND: Highly increased risk of injuries has been noted around the time of cancer diagnosis. Whether there is a similar increase in risk around the diagnosis of cervical cancer and its precursor lesions was unknown.METHODS: We performed a cohort study including 3,016,307 Swedish women that participated in cervical screening during 2001 to 2012. We calculated the incidence rates (IR) of hospit
Screening for atrial fibrillation (AF) with a handheld device for recording the ECG is becoming increasingly popular. The poorer signal quality of such ECGs may lead to false detection of AF, often caused by transient noise. Consequently, the need for expert review in AF screening can become extensive. A convolutional neural network (CNN) is proposed for transient noise identification in AF detect
Swedish small-scale fishing has undergone significant changes over time. There are examples of small-scale fishers who have diversified their activities by developing new sales channels or by processing a large part of their products themselves. However, this type of activity is significantly less well-documented than the fishing itself. In this paper, we examine how the catches of the Swedish sma
Di-isobutylene has received significant attention as a promising fuel blendstock, as it can be synthesized via biological routes and is a short-listed molecule from the Co-Optima initiative. Di-isobutylene is also popularly used as an alkene representative in multi-component surrogate models for engine studies of gasoline fuels. However, there is limited experimental data available in the literatu
This paper shows that the socio-technical barriers that sustainable innovations face, may stem from global regimes. Existing transitions approaches like the Technological Innovation System (TIS), overlook the impact of global regimes on radical innovation. Building on institutional theory, we therefore develop a theoretical framework that captures TIS-regime interaction, allowing us to analyze the
Background: Traumatic peripheral nerve injury is common and incurs significant cost to individuals and society. Healing following direct nerve repair or repair with autograft is slow and can be incomplete. Several bioengineered nerve wraps or devices have become available as an alternative to direct repair or autologous nerve graft. Nerve wraps attempt to reduce axonal escape across a direct repai
Objectives: The use of patient-reported outcome (PRO) measured outside clinical trials is not well defined. We report the first analysis of the prospective PRO study within the Swedish acute myeloid leukemia (AML) and the acute lymphoblastic leukemia (ALL) registries. Methods: PRO was requested 6 months after diagnosis. The EORTC Quality of life Questionnaire Core 30-item, the Patient Health Quest
