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In this 12-month multicenter Scandinavian study, 78 maintenance heart transplant (HTx) recipients randomized to everolimus with reduced calcineurin inhibitor (CNI) exposure or continued standard CNI-therapy underwent matched virtual histology (VH) examination to evaluate morphological progression of cardiac allograft vasculopathy (CAV). Parallel measurement of a range of inflammatory markers was a

76 patients were examined clinically and radiologically 27 to 36 years after a fracture of the distal radius. The average age was 31 years at the time of injury and 63 years at follow-up. In 81% of the patients there was no difference between the fractured and the non-fractured side. No patient had to change his or her occupation or leisure activities because of the fracture. There were more degen

Mitigation of vasomotor symptoms and urogenital problems, along with reductions in osteoporosis and cardiovascular disease, provides the rationale for using hormone replacement therapy (HRT), and the duration of use. However, user surveys have indicated poor compliance with HRT, and that means user time may be less than 12 months, a period unlikely to influence metabolic disorders. The main reason

Objectives. Environmental risk factors are of potential interest for both prevention and treatment of RA. The purpose of this study was to examine the effect of pulmonary function, smoking and socio-economic status on the future risk of RA. Methods. Between 1974 and 1992, 22 444 men and 10 902 women were included in the Malmö Preventive Medicine Program (MPMP). Pulmonary function was assessed by a

Background: Prevention of arthropathy is a major goal of hemophilia treatment. While studies in adults have demonstrated an impact of prophylaxis on the incidence of joint bleeds and patients' well-being in terms of improved quality of life (QoL), it is unclear whether or not prophylaxis influences the outcome and well-being perception of children with hemophilia. Objective: This randomized contro

BACKGROUND: Optimal care for children with HIV infection includes timely assessment of treatment failure. Using HIV viral load to define treatment failure remains a challenge in resource-limited settings.METHODS: Children with HIV infection who were already on or starting first-line antiretroviral therapy were enrolled and followed over time. We examined clinical and immunologic predictors of viro

Climate change is identified as a major threat to wetlands. Altered hydrology and rising temperature can change the biogeochemistry and function of a wetland to the degree that some important services might be turned into disservices. This means that they will, for example, no longer provide a water purification service and adversely they may start to decompose and release nutrients to the surface

The atrioventricular (AV) node plays a crucial role during many supraventricular tachycardias (SVT). To better understand its function under these complex conditions, mathematical modelling has emerged as a valuable tool. The model presented here builds on a recently published 1D model of the human AV-node, consisting of a series of interacting nodes, each with separate dynamics in refractory time

The conversion of technical lignin into valuable chemicals is important for the complete utilization of lignocellulose. The kraft process dominates the pulp industry, and large amounts of kraft lignin are produced worldwide. However, the complexity of lignin limits its valorization. In this study, a kraft lignin, Indulin AT, was depolymerized under base conditions, and the effects of substrate loa

Nitrogen (N) availability is a powerful controller of soil carbon (C) cycling in temperate forests, affecting plant productivity and microbial activities. Enhanced rhizosphere input from increased plant productivity can stimulate the decomposition of native soil organic matter (SOM), termed the “priming effect”, with an effect size that is affected by N availability. Using soils from N-fertilizati

Tumor growth rate estimations can provide useful information about tumor progression and aggressiveness. Understanding the breast cancer progression and aggressiveness could aid with personalized screening/follow-up, treatment options, and prognosis. This paper reports a preliminary estimation of the tumor volume doubling time (TVDT) for cancers detected during the Malmö Breast Tomosynthesis Scree

Objective: To examine the association of physical activity (PA), measured by accelerometry, to hemoglobin AIC (HbA1c) and oral glucose tolerance test (OGTT) outcomes in children who were multiple persistent confirmed autoantibody positive for type 1 diabetes (T1D). Methods: The Environmental Determinants of Diabetes in the Young (TEDDY) multinational study followed children from birth. Children ≥3

The existence or absence of motivation among project members can determine whether or not a project succeeds or fails. Establishing and maintaining motivation, however, are difficult tasks for project managers. Individuals have different triggers of motivation and it is a complex task to understand the underlying motivational drivers of every member of a project, especially because projects are ch

Primary cultures of cells from late pregnant rat myometrium contain B2 kinin receptors through which bradykinin (BK) stimulates inositol phosphate (InsP) formation and arachidonic acid (20:4) release. Equilibrium binding at 4°C revealed that [34H]BK identified a maximal number of cell surface B2 kinin receptor binding sites on rat myometrial cells of 308 ± 78 fmol/106 cells with apparently a singl

Perovskite solar cells have rapidly been developed over the past several years. Choice of the most suitable solar cell structure is crucial to improve the performance further. Here, we attempt to determine an optimum cell structure for methylammonium lead iodide (MAPbI3) perovskite sandwiched by "2 and spiro-OMeTAD layers, among planar heterojunction, mesoporous structure, and extremely thin absor

Till följd av den pågående energikrisen har vi under 2022 upplevt skenande elpriser och hot om bortkoppling av kunder från elnätet. Nya lösningar som säkerställer tillgång på el och balans i elnätet är nödvändiga. En lösning som visar stor potential är lagring av energi i vätgas. En av utmaningarna som Sveriges elnät står inför, och som det pratats mycket om den senaste tiden, är effektbrist. EffWith climate change as the main driving force, the energy system is currently undergoing changes. Both the share of renewable resources used to produce electricity and the overall electrification is increasing. A way to handle the resulting challenges from more intermittent electricity production is by the implementation hydrogen technology. Hydrogen technology can help balance the electricity net

I denna studie har vi intervjuat tre kvinnor som levt under riskfyllda förhållanden i form av missbruk i större delar av sitt liv. Syftet med vår uppsats var att undersöka vilka erfarenheter anhöriga till missbrukare har av självhjälpsgrupper av typen ACA (vuxna barn till alkoholister och från andra dysfunktionella familjer) och dess stöd och hjälp. Vi formulerade tre frågeställningar där vi villeIn this study, we interviewed three women who have lived in hazardous conditions such as abuse in the greater part of their lives. The aim of this study was to examine what experiences relatives of abusers have of self-help groups such as ACOA (Adult Children Of Alcoholics and of other dysfunctional families) and its support and help. Due to our purpose we asked ourselves three questions: 1. how d

Sexual violence is a frequent problem in armed conflict. For twenty years, multiple measure have been adopted to stop this conduct but it is showing very little result. At the same time, there is a lively debate on several areas concerning sexual violence in armed conflict. This thesis analyses two of these areas of debate in order to find what the Community of States is doing wrong. Before enter

The case Micula gave people the impression that EU law and ICSID arbitration law are incompatible legal orders, unable to accept each other’s dissenting opinions. Every ICSID tribunal decision in the field seems to cause heavy defence reactions in the EU legal system. However, this clearly does not have to be the case if all parties involved behave cautiously. This thesis will analyse in detail

It seems that people are more disconnected to the objects they own than ever before. What has changed in the last decades? People had tools and the skills to use them, but due to convenience and easy consumable entertainment, do-it-yourself was replaced by do-it-forme. Tasks we would have handled ourselves in the past are now done by a product or a service. This is disabling people. By losing ski