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HAMLET (human alpha-lactalbumin made lethal to tumor cells) is a tumoricidal complex consisting of partially unfolded protein and fatty acid, and was first identified in casein fractions of human breast milk. The complex can be produced from its pure components through a modified chromatographic procedure where pre-applied oleic acid binds with partially-unfolded alpha-lactalbumin on the stationar
The genetic basis of complete C4 deficiency in a patient with SLE was investigated. Previous studies have demonstrated that this patient has two different major histocompatibility complex (MHC) haplotypes that each contain a major deletion and a non-expressed C4 gene. In the present study, non-expression of the C4 genes was explained by the finding of two distinct C4 gene mutations. A previously d
Genetic susceptibility to insulin resistance is associated with lower adiposity in adults. Insulin resistance, and therefore adiposity, may alter sensitivity to Growth Hormone (GH). We aimed to determine the relationship between adiposity, genetic susceptibility to insulin resistance or insulin secretion, and response to GH treatment in short children born small for gestational age (SGA).
We report the implantation of the Berlin Heart EXCOR (Berlin Heart, Berlin, Germany) as a pediatric biventricular assist device in a 10-month-old boy with primary graft failure after cardiac transplantation. The EXCOR was successfully used as a bridge to cardiac retransplantation. The pneumatically driven paracorporeal device supported the patient for 165 days until another suitable heart was obta
The ICAO approach to risk management is essentially a technical model based on an engineering process viewpoint and is more applicable in concept to stable systems, such as chemical and nuclear industries. If airlines are to manage risk in a proactive manner they need to apply risk detection tools that provide real time and continuous systems oversight. This paper describes briefly the systems ap
Our hypothesis was that carbohydrate, fat, and protein contents of meals affect satiety, glucose homeostasis, and hormone secretion. The objectives of this crossover trial were to examine satiety, glycemic-insulinemic response, and plasma peptide levels in response to 2 different recommended diabetes diets with equivalent energy content. One traditional reference breakfast and one test breakfast,
Hej! (Information in English below) Saco-S bjuder in alla medlemmar till tre föreläsningar (på svenska) om lärares arbetstid, upphovsrätt och om pensionssystemet. Föreläsningarna ordnas av vårt kontaktförbund SULF. 5 oktober: Arbetstid: Du kan alltid jobba lite mer? För att uppmärksamma SULF-dagen arrangerar SULF vid Göteborgs universitet en föreläsning med efterföljande panelsamtal om arbetstid f
Stress påverkar kärlen mer än man tidigare trott – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Stress påverkar kärlen mer än man tidigare trott 2012-05-25 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Stress är ohälsosamt och dåligt f
https://www.vetenskaphalsa.se/stress-paverkar-karlen-mer-an-man-tidigare-trott/ - 2026-07-17
Currently facing the problems of security of supply and higher electricity prices in southern Sweden, a medium-large power plant is considered to be built. To prepare for the possible outcome, a study of different cycle configurations was conducted. The study analyzed a 500 MWeldistrict heating mode power plant based on the Avedare power plant in Denmark, a single reheat Rankine cycle with a heat
Background: Digital work can be cognitively challenging especially for people with cognitive difficulties. New occupational therapy interventions are needed to empower these persons to self-manage challenges in digital work and everyday life. To address this need, the internet-based intervention 'Strategies for Empowering Activities in Everyday Life' (SEE 2.0) was tested.Aim: To explore and descri
OBJECTIVE: Sepsis and septic shock are major challenges and economic burdens to healthcare, impacting millions of people globally and representing significant causes of mortality. Recently, a large number of quality improvement programs focused on sepsis resuscitation bundles have been instituted worldwide. These educational initiatives have been shown to be associated with improvements in clinica
A growing body of observations has revealed rapid changes in both the total inventory and the distribution of marine oxygen over the latter half of the 20th century, leading to increased interest in extending oxygenation records into the past. The use of paleo-oxygen proxies has the potential to extend the spatial and temporal range of current records, constrain pre-anthropogenic baselines, provid
For researchers studying wildlife distributions of the past, the assignment of faunal depictions and remains to species can often present considerable challenges. Regrettably, many studies do not systematically consider all options and sources of evidence and, as a result, questionable identifications are widespread in the literature, which compromises the trustworthiness of meta-analyses of human
Object. Acromegaly is a disease that has significant morbidity and mortality related to high levels of growth hormone (GH) and insulin-like growth factor-I (IGF-I), and is usually caused by pituitary adenomas. The goal in this study was to investigate the role of endoscopic transsphenoidal surgery and surgical experience in the treatment of GH adenoma cases in relation to surgical results and horm
Over the past two decades, caesarean section rates have been steadily increasing with rates are now approaching 55% in some European countries. While caesarean section remains one of the most critical obstetric interventions, often lifesaving for both mother and newborn, it also carries significant risks for maternal and neonatal health. The growing reliance on caesarean birth is further linked to
This paper presents findings from real life situations, a longitudinal single case study on the role of natural environments in nature-based rehabilitation (NBR) for individuals with stress-related mental disorders, at the Alnarp Rehabilitation Garden in Sweden. A sample of 43 former clients voluntarily participated in semi-structured interview, and the data were analyzed according to interpretati
Residential segregation is seen as a growing problem within many urban areas today. Segregation is assumed to hamper social integration and the life-chances of disadvantaged as well as creating instability in society. One policy measure to deal with residential segregation is to increase the variation in the housing structure. This is assumed to create a social mix, that in turn will generate posi
A search for pair production of vector-like leptons coupling to first- and second-generation Standard Model leptons is presented. The search is based on a dataset of proton-proton collisions at s = 13 TeV recorded with the ATLAS detector during Run 2 of the Large Hadron Collider, corresponding to an integrated luminosity of 140 fb−1. Events are categorised depending on the flavour and multiplicity
