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Popular Abstract in Swedish Hudcancerformen malignt melanom är en utav de cancerformer som är på starkast frammarsch idag, där runt 200,000 människor drabbas varje år runt om i världen. Sjukdomen uppkommer p.g.a. förändringar i arvsmassan (DNA) hos en speciell typ av celler som finns i huden, de så kallade melanocyterna. Under normala förhållanden har dessa celler till uppgift att producera det brThe life-threatening disease of malignant melanoma is one of the fastest growing forms of cancer, affecting an estimated number of 200,000 patients worldwide every year. Although highly curable if detected early, once the melanoma has metastasized there are few treatment options and a median survival rate of only 6-9 months. Consequently, there is an imperative need to identify the factors that dr

Popular Abstract in Swedish Hjärnan är ett av människans viktigaste organ och är det centra som styr våra känslor, minnen och sociala färdigheter. Hjärnan är också det organ som signalerar till musklerna i kroppen att utföra rörelser. När en person drabbas av Parkinsons sjukdom minskar signaleringen till musklerna, vilket medför att det blir svårt att röra sig och stelhet uppstår. Sjukdomen beror Cell-replacement therapy is a promising approach for treating patients with Parkinson ́s disease (PD). For this purpose, there is a need for developing a protocol that can generate high numbers of human transplantable mesencephalic dopaminer- gic (mesDA) neurons. For decades, studies have therefore been made in mouse and other model organisms in order to elucidate key-factors that can be used for

Introduction: It is well established that managing patients with acute stroke in dedicated stroke units is associated with improved functioning and survival. The objectives of this study are to investigate whether patients with acute stroke are less likely to be directly admitted to a stroke unit from the Emergency Department when hospital beds are scarce and to measure variation across hospitals

AbstractBlind, I. 2015. Essays on Urban Economics. Economic studies 153. xii+199 pp. Uppsala:Department of Economics. ISBN 978-91-85519-60-6.This thesis consists of four self-contained essays.Essay 1 (with Olof Åslund and Matz Dahlberg): In this essay we investigate the impact ofcommuter train access on individual labor market outcomes. Our study considers the exogenousintroduction of a commuter t

BACKGROUND: Timely assessment of the burden of HIV/AIDS is essential for policy setting and programme evaluation. In this report from the Global Burden of Disease Study 2015 (GBD 2015), we provide national estimates of levels and trends of HIV/AIDS incidence, prevalence, coverage of antiretroviral therapy (ART), and mortality for 195 countries and territories from 1980 to 2015.METHODS: For countri

In total 14 bulk atmospheric deposition collectors were distributed over the city of Lund (about 20 km~) in the south of Sweden during September 1980 to June 1981. The observations were made to investigate small-scale spatial variability of atmospheric deposition. Monthly bulk deposition samples were analyzed for CI, Ptot, Zn, Cu, and Pb.Correlation analysis shows that the spatial scale for the va

Sea salt aerosol particles are highly abundant in the atmosphere and play important roles in the global radiative balance. After influence from continental air, they are typically composed of Na+, Cl-, NH4+, and SO42- and organics. Analogous particle systems are often studied in laboratory settings by atomizing and drying particles from a solution. Here, we present evidence that such laboratory st

This paper presents a comprehensive evaluation of various wireless networks for Teleoperated Driving (ToD) applications, focusing on a hoverboard as a test vehicle. The study compares end-To-end delay and jitter across five network setups: A private 5 G network, a wireless LAN, a public LTEA network, and two wireless CANs, based on the service level requirements outlined by the 5G Automotive Assoc

Industrial Control Systems (ICS) have been compromised by cyber-attacks with the development of computer and network technologies over the past few decades. Intrusion Detection Systems (IDSs) play a significant role in ensuring information security, and the key mechanism is to identify various attacks in the network accurately. One common strategy when implementing an IDS is to use a machine-learn

Current criteria for the diagnosis of CKD in adults include persistent signs of kidney damage, such as increased urine albumin-to-creatinine ratio or a GFR below the threshold of 60 ml/min per 1.73 m2 This threshold has important caveats because it does not separate kidney disease from kidney aging, and therefore does not hold for all ages. In an extensive review of the literature, we found that G

Noroviruses are the major cause for viral acute gastroenteritis in the world. Despite the existing infection prevention strategies in hospitals, the disease continues to spread and causes extensive and numerous outbreaks. Hence, there is a need to investigate the possibility of airborne transmission of norovirus. In this study, we developed an experimental setup for studies on the infectivity of a

Even though the European Union has promoted multilingualism for long, it has proven difficult to achieve widespread multilingual language competence beyond English through formal education in Europe. In Sweden, high dropout rates have been recorded in second foreign language (SFL) classes and French is currently the most vulnerable language among the major SFLs with respect to number of pupils and

We created an AI support for diagnosis in dyspneic adults at time of triage in the emergency department.Complete data from an entire regional health care system was analyzed, to find AI-derived, unknown, important diagnostic predictors. Most important were prior diagnoses of heart failure or COPD, daily smoking, atrial fibrillation/flutter, life difficulties and maternal care.Sensitivity for AHF,

Sustainability science emerged as a new academic field to address complex sustainability challenges. To train sustainability experts, sustainability science programs and sustainability-focused courses are offered in higher education, especially at the graduate level. Given the diverse topics and the complex structures of sustainability challenges, what are the required knowledge and skills needed

People appear to vary in their susceptibility to lifestyle risk factors for cardiometabolic disease; determining a priori who is most sensitive may help optimize the timing, design, and delivery of preventative interventions. We aimed to ascertain a person's degree of resilience or sensitivity to adverse lifestyle exposures and determine whether these classifications help predict cardiometabolic d

Coherent InP nano-sized islands, embedded into GaInP, have been grown by metal-organic vapour phase epitaxy using the Stranski-Krastanow growth mode. Photoluminescence, atomic force microscopy and transmission electron microscopy studies show that the insertion of a thin ∼ 4 monolayer thick GaP layer affects the critical thickness of the subsequently deposited two-dimensional InP wetting layer, in

Exposure to natural environments is thought to benefit mental and physical health. A better understanding of the interplay between the individual and the environment in relation to public health is imperative in light of the joint biodiversity, climate, and health crises. This study aimed to 1) identify Body Mass Index (BMI) trajectories in the Scania Public Health Cohort (SPHC), 2) characterise t