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BACKGROUND: Many studies have indicated that colon and rectal cancers differ in etiology and histology. OBJECTIVE: The aim of this study was to investigate whether the associations of colon and rectal cancers with any other (discordant) cancer were site specific. DESIGN: A novel approach was implemented in which cancer risks were analyzed in families with increasing numbers of family members diagn
Computers and digital instruments change the way we think about ourselves and other people, demonstrated by an example with a girl who imagined that she had a computer in her brain where she could click on “Music” in the menu to hear music. This chapter argues that good music technology should allow play and unpredictable events and support a balance between challenge and ability. Digital instrume
This chapter explores how nursing home managers grapple with local manifestations of the wicked problems that plague elderly care. It shows the tension between managers' lofty ideals of high-quality, individualized care and their continuous struggle to handle very basic troubles that ultimately appear to be grounded in a lack of resources, such as high personnel turnover and staff complaints about
In particular, I look at how traces of Zhuangzi’s butterfly dream appear in the oneiric fictions of Argentinian writer Jorge Luis Borges, and how, in turn, Borges’ dream-worlds have inspired Chinese author Can Xue to create a new kind of literary dreamscape.
Aims Genetic testing is needed for the formal diagnosis of maturity-onset diabetes of the young (MODY), but this is not widely available. If any MODY biomarkers were known, these could possibly be used as an alternative. Hepatocyte nuclear factor (HNF)-1alpha and HNF-4alpha regulate transcription of genes encoding complement 5 (C5), complement 8 (C8) and transthyretin (TTR), suggesting that these
Background The complex carbohydrate composition of natural and refined plant material is not known in detail but a matter that is of both basic and applied importance. Qualitative assessment of complex samples like plant and wood tissues requires the availability of a range of specific probes. Monoclonal antibodies and naturally existing carbohydrate binding modules (CBMs) have been used in the pa
Males should invest in mate attraction, mate guarding and paternal care in relation to the marginal fitness value of each of those behaviours. Since time and energy are limited, trade-offs between these activities are expected. This study demonstrates that monogamous male European starlings (Sturnus vulgaris) decrease their paternal effort in response to increased opportunities to attract addition
Bergh considers the relationship between migration and interpersonal trust in the European Union. Interpersonal trust, Bergh avers, is an important foundation for a well-functioning society. The question is how interpersonal trust is affected by increased migration in countries with differing levels of trust. Bergh shows that migrants from low-trust countries who move to high-trust ones show highe
Hannah Persson’s essay looks at the early reception in England of Denmark’s most famous writer Hans Christian Andersen, showing how Andersen was (mis)represented in England as a result of the particular inflection given to his work by his translator, Mary Howitt. Examining Howitt’s praxis as a translator, Persson concludes that her (mis)understanding of Andersen’s tales as primarily intended for c
This paper reports on a one-to-one relation between articulation and acoustics. It explains how segment boundaries are a result of rapid movements of the articulators. In the acceleration profile, this is identified as peak acceleration, which can be measured. A previous study found that rapid movements of an active articulator - peak acceleration - correlate with the acoustic segment boundary in
