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Background Subclinical cobalamin deficiency is common in the elderly, but the sensitivity and specificity of serum total cobalamin for this diagnosis is poor. Serum holotranscobalamin (holoTC), a measure of biologically available cobalamin, is considered a better marker for early cobalamin depletion than total cobalamin. However, in elderly populations, health-related reference intervals for holoT
The purpose of the thesis is to investigate how the semiconductor industry will develop during the period 2007-2012. Issues: The main issues presented are: • How will the competitive landscape change from 2007 to 2012? • How will companies succeed in the industry in 2012? • What position will the Integrated Device Manufacturers take in the value chain in 2012? Method: In order to achieve the purpo
The main purpose of this was to examine the current Chinese satirical/political cartoons by studying anti-corruption cartoons. Also, to answer the question from an online discussion about “whether there are satirical cartoons (讽刺漫画) in China today”. The study follows the concept of political cartoons as a medium of politics and society. The information and the hidden meaning of the cartoons are ex
South Korea has gone from a military dictatorship to being the highest-ranking Asian country in terms of democracy over the last 35 years. In 2016, massive social movement protests broke out after media uncovered accounts of widespread corruption by then President Park Geun-Hye. These public demonstrations become known as the Candlelight movement of 2016-2017, lasting for six months to culminate i
Differences in political orientation are partly rooted in personality, with left-wing political attitudes being predicted by Openness to Experience and right-wing attitudes by Conscientiousness. This has been validated across numerous studies from different countries. This essay adds to that body of research by examining whether personality differences between the political sides also exist in the
This thesis evaluates the evidence for the absolute-income hypothesis (AIH), relative-income hypothesis (RIH) and income-inequality hypothesis (IIH) in Australia using individual level panel data from the first 11 waves of The Household, Income and Labour Dynamics in Australia (HILDA) Survey under General Release 11. The analysis is performed with an individual fixed effects estimation and the int
In September 2015, the OECD released the final report on BEPS action 6. The main purpose of the action 6 is the prevention of "granting treaty benefits in inappropriate circumstances". Regarding the prevention of treaty abuse the OECD presented three main recommendations. These actions are only proposals and therefore they constitute soft law. However with their implementation in the tax
This paper empirically investigates the relationship between education and risk of developing dementia. From a large body of literature, it is well known that higher education associates with better health. This is true both for health in general, but also for more specific diseases like Alzheimer’s. However, the question of whether the link between years of education and dementia is causal or not
Modern slavery is connected to the global trade and company supply chains. This essay aims to examine how this is regulated and addressed today, from a legal and corporate social responsibility (CSR) perspective, and analyse the extent to which such obstacles can be overcome. To reach the aim of this study, a traditional legal dogmatic method, together with an empirical method in the form of a cas
Purpose: This study intends to explore how video games companies work with strategic brand management. Methodology: A qualitative literature review and case study of Blizzard Entertainment using Kapferer’s Brand Identity Prism. The data was collected from Blizzard as well as other secondary sources. Findings: The findings of this paper shows that Kapferer’s Brand Identity Prism was applicable to t
By screening blood samples from patients with autosomal dominant retinitis pigmentosa, we found in one of the families a rhodopsin mutation (Pro-267-Leu), which segregates with the disease in two affected and five unaffected family members. Here, we present the results of the clinical evaluation of the family, including full-field electroretinography from the two affected family members. A 25-year
To investigate a putative involvement of protein kinase C (PKC) isoforms in supporting neuroblastoma cell proliferation, SK-N-BE(2) neuroblastoma cells were transfected with expression vectors coding for the C2 and V5 regions from different PKC isoforms. These structures have been suggested to inhibit the activity of their corresponding PKC isoform. The PKC fragments were fused to enhanced green f
Under anaerobic conditions S. cerevisiae produces glycerol to regenerate NAD+ from the excess NADH produced in cell metabolism. We here report on the role of an uncharacterized protein, Yig1p (YpI201cp), in anaerobic glycerol production. Yig1p was previously shown to interact in two-hybrid tests with the GPP1 and GPP2 encoded glycerol 3-phosphatase (Gpp), and we here demonstrate that strains overe
The aim of this study was to collect new knowledge about the importance of signal crayfish predation on zebra mussels in Lake Erken. Possibly with implications on biological control of the invasive species in Swedish lakes. I performed a field experiment with enclosures (including signal crayfish) and exclosures (without signal crayfish) during 11 summer weeks in Lake Erken. My results showed that
Estimating the spatial extent of the impacts of renewable energy infrastructure on tourism is crucial for the identification of potential locations of resource use conflict. Such a task, however, is complicated and requires inclusion of social perceptions on the spatial extent of the impacts. This study investigates perceptions of the tourism industry in Iceland regarding the impact area of existi
Accurate communication of the severity of violence in intimate relations is essential for the appropriate evaluation of offenders and victims in contexts such as court trials, custody cases, and the continuation of relationships. Using a new paradigm, this study quantifies discrepancies in how the severity of violence is communicated in texts written by offenders, victims, and bystanders who witne
There is a close relationship between the SARS-CoV-2 virus and lipoproteins, in particular high-density lipoprotein (HDL). The severity of the coronavirus disease 2019 (COVID-19) is inversely correlated with HDL plasma levels. It is known that the SARS-CoV-2 spike (S) protein binds the HDL particle, probably depleting it of lipids and altering HDL function. Based on neutron reflectometry (NR) and
Facilitated by mobility, occupational participation outside the home is vital in old age. However, the relative importance of factors influencing mobility and occupational participation remains unclear. The present study describes older peoples’ motives for, and experiences of, mobility and occupational participation outside the home. Nine focus-group interviews were conducted and analyzed using c
