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The Wilms' tumor gene 1 (WT1) is recurrently mutated in acute myeloid leukemia. Mutations and high expression of WT1 associate with a poor prognosis. In mice, WT1 cooperates with the RUNX1/RUNX1T1 (AML1/ETO) fusion gene in the induction of acute leukemia, further emphasizing a role for WT1 in leukemia development. Molecular mechanisms for WT1 are, however, incompletely understood. Here, we identif

In the cinemas of small European nations, infrastructural support systems aimed at endorsing and strengthening audiovisual production, tend to play an increasingly pivotal role. Since additional systems have been added, with the intent to, for instance, encourage co-production or to attract filming and post-production work to assorted places – and always coming with various provisions attached – o

In order to qualify a subscriber loops for xDSL transmission, basic parameters like transfer function, scattering parameter S11 and characteristic impedance should be known. The aim of this paper is to present a test methodology for measurements of these basic parameters. The characteristic impedance is measured by open/short method and it is compared with the terminated measurement method defined

Introduction: Using time-limited trials of low-dose, sustained-release morphine to reduce chronic breathlessness to evaluate net effects may generate opioid withdrawal symptoms if medication is ceased. This sub-study of a larger randomized, placebo-controlled, double-blind trial aimed to evaluate if this occurred. Methods: People with modified Medical Research Council breathlessness scores of 3 or

The sheet metal forming process is integral to the automotive industry, producing a variety of components essential for vehicle construction, including body panels, chassis parts, and structural supports. The process involves shaping thin metal sheets into desired forms using techniques such as bending, stretching, drawing, and stamping. In order to build high quality cars it is vital with an effi

A primary functionality of context aware applications is the retrieval of different types of context data from various context sources and adapting their behavior accordingly. In order to facilitate context aware application development, a context aware middleware must provide an effective context data management and lookup strategy. The use of a traditional index for indexing dynamic context data

Background: A number of trends during the last decade, like globalisation, outsourcing, single sourcing, leanness and agility, have made the supply chain more vulnerable and “supply chain risk management” has become a research area of its own. Objective: To characterize the existing scientific knowledge and scientific knowledge creation within supply chain risk management as it is presented in the

Popular Abstract in Swedish De svenska framtidsuttrycken (futuralt presens, futuralt skola och futuralt komma) är alla kontextuellt betingade användningar av uttryck som också har andra funktioner. Syftet med min avhandling är att beskriva vilka kontextvillkor som måste vara uppfyllda för att de tre uttrycken ska fungera som framtidsuttryck. I den modell över svenskans temporala system som presentThe main aim of this study is to specify the contextual conditions that apply to the use of the three central expressions for the future in Swedish: the present form and the auxiliaries skola and komma. A tense suffix indicates a temporal domain and states that a mediating element, here called FIX, is placed in the indicated domain. The present suffix points to a domain that overlaps temporally wi

Multimodal transportation in the European continent is an integral part of cross border trade and in particular the use of sea and river carriers. The phenomenon of short sea shipping has reached a level of importance of which all European states must take cognisance. One of the policies associated with this issue is the development of the motorways of the sea. While Ukraine is not yet a part of t

In the autumn of 2011, the course “The City: Boundary Transgressions and Visual Expressions” was given for the first time. Formally placed at the Division of Art History and Visual Studies, the course is a collaboration with the Division of Social Anthropology and is directed towards students from a range of disciplines within the fields of the humanities and social sciences. The course includes

The resurgence of artificial intelligence (AI) has empowered organizations to concentrate their research efforts on enhancing decision-making and automation capabilities. This is being pursued with the goal of increasing productivity, whilst reducing costs. With this, it is perceived that the jobs within these organizations that are considered subject to ‘routine’, or repetitive and mundane tasks,

The use of interactive visualization techniques in Digital Humanities research can be a useful addition when traditional automated machine learning techniques face difficulties, as is often the case with the exploration of large volumes of dynamic—and in many cases, noisy and conflicting—textual data from social media. Recently, the field of stance analysis has been moving from a predominantly bin

We demonstrate the generation and in-situ measurement of the electric field and CEP of intense near-single-cycle laser pulses using the new optical technique of CEP dispersion-scan.

AIM: To study to what extent tumor-specific treatment (chemo- or radiotherapy) was given during the last 30 days in life and to examine how many of the patients were referred to a specialized palliative care unit (PCU), at a low-resource governmental hospital in India.PATIENTS AND METHODS: Medical records of adult cancer patients deceased between April 1 and May 31 in 2016, and pediatric cancer pa

Phase contrast micro-CT is a powerful technique allowing imaging of soft tissue at synchrotrons or using lab- oratory sources. The use of contrast agents is a useful approach when imaging vascular structures. However, common x-ray contrast agents typically rely on heavy metals to increase absorption, which may affect the phase contrast and cause artifacts in the reconstructed volumes. Thus, utiliz