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Peptides constitute alternative molecules for the treatment of infections caused by bacteria, viruses, fungi, and protozoa. However, their therapeutic effectiveness is often limited by enzymatic degradation, chemical and physical instability, and toxicity toward healthy human cells. To improve their pharmacokinetic (PK) and pharmacodynamic (PD) profiles, novel routes of administration are being ex

This thesis delves into Louis Spohr and his First Concerto for Clarinet and Orchestra, Op. 26, starting with an overview of the composer's life and his work. The analysis will provide a better understanding of the meaning and characteristics of this composer's writing during his musical career. The thesis also explores the performance of his concerto that is closer to the composer’s origin

För mer information, se projekten "Hjärttransplantation" och "Lungtransplantation"For more information, please see the projects "Heart Transplantation" and "Lung Transplantation"

Affärsrättsligt centrum vid Lunds universitet, ACLU , bildades 2016 av förmögenhets- och affärsrättsligt verksamma forskare vid Lunds universitet. Avsikten med ACLU är att såväl samla som stärka de vitala och kraftfulla forskningsmiljöer på det affärsjuridiska området som finns inom Lunds universitet och göra dem såväl nationellt som internationellt konkurrenskraftiga. För en framgångsrik forskninLund University Centre for Business Law (Swedish abbr: ACLU) was founded in 2016 by researchers at Lund University. The purpose of ACLU is both to assemble and to strengthen the necessary and forceful research environments that exist at Lund University, and to make them both nationally and international competitive. An intense exchange of experiences and knowledge between the University and the pu

Bröstcancer är den vanligaste cancerformen bland kvinnor. Ovarialcancer upptäcks ofta sent och prognosen är därför dålig. Den relativa 5-årsöverlevnaden är mindre än 50%, jämfört med >80% för bröstcancer. Den idag rådande uppfattningen är att det som kallas ovarialcancer i själva verket är olika sjukdomar, med skillnader i var de uppkommer, vilka egenskaper de har och hur de svarar på behandling. Breast and ovarian cancers are complex and heterogeneous, and share several features, including genetic predisposition caused by BRCA1/2 mutations. Ovarian cancer is however associated with poor survival relative to breast cancer. Utilizing comprehensive biobanks, high-throughput omics methods and in vitro model systems we aim to advance our understanding of tumour evolution, disease heterogeneity

Avdelningen för partikel- och kärnfysik spänner brett över subatomär fysik och agerar till stor del inom internationella forskningsmiljöer. Vi bedriver experimentell och teoretisk forskning med kolliderexperiment. Vi sysslar med sökningar av mörk materia, grundläggande fysik med neutroner, kärnstruktur och kärnreaktioner på gränsen för kärnstabilitet, samt studerar konstgjord radioaktivitet i miljThe Division of Particle and Nuclear Physics spans broad across subatomic physics and acts largely within international research environments. We conduct experimental and theoretical research with collider experiments. We are engaged in dark-matter searches, fundamental physics with neutrons, nuclear structure and nuclear reactions at the limits of nuclear stability, as well as studying man-made r

Forskarna inom detta område arbetar med forskning om bruk, skadligt bruk och beroende av alkohol och andra droger, ofta ur ett socialvetenskapligt perspektiv. Även beroendeproblem kopplade till spel om pengar och dopning berörs. Forskningen rör såväl människors livsvillkor och erfarenheter som vårdens, socialtjänstens och andra samhällsaktörers arbete. Forskningen har en bred metodologisk ansats oResearchers in this area study the use, harmful use, and dependence on alcohol and other drugs, often from a social science perspective. Gambling-related addiction problems and doping are also included. The research addresses both people’s living conditions and experiences, and the work of healthcare services, social services, and other societal actors. It takes a broad methodological approach and

Currently, the focus of the group’s research has been on the relationship between room acoustics and voice use in teachers. This work, supported by AFA insurance, examines the prevalence and aetiology of voice disorders in teachers in Southern Sweden, applying a blend of techniques: questionnaires, high-speed laryngeal imaging, acoustic and perceptual voice analysis, and field studies of voice useCurrently, the focus of the group’s research has been on the relationship between room acoustics and voice use in teachers. This work, supported by AFA insurance, examines the prevalence and aetiology of voice disorders in teachers in Southern Sweden, applying a blend of techniques: questionnaires, high-speed laryngeal imaging, acoustic and perceptual voice analysis, and field studies of voice use

Vårt övergripande forskningsmål är att hitta nya sätt att behandla patienter med metastaserande bröstcancer. Även om stora framsteg i hur vi behandlar bröstcancerpatienter har gjorts under de senaste decennierna så får många patienter fortfarande återfall och metastaserande bröstcancer är fortfarande en obotlig sjukdom. Genom att identifiera signalvägar som är aktiva i metastaser och studera riktaOur ultimate research goal is to find improved ways to treat patients with metastatic breast cancer. Although significant progress in treatment strategies has been made during the last decades, many breast cancer patients still relapse and to date metastatic breast cancer remains an incurable disease. We aim to identify the signalling pathways active in recurrent disease in order to study response