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Background: Parkinson's disease (PD) is one of the most common neurodegenerative diseases, neuropathologically characterized by misfolded protein aggregation, called Lewy bodies and Lewy neurites. PD is a slow-progressive disease with colonic dysfunction appearing in the prodromal stage and lasting throughout the course of the disease. Methods: In order to study PD pathology in the colon, we exami
Microorganisms dominate the decomposition of organic matter and their activities are strongly influenced by temperature. As the carbon (C) flux from soil to the atmosphere due to microbial activity is substantial, understanding temperature relationships of microbial processes is critical. It has been shown that microbial temperature relationships in soil correlate with the climate, and microorgani
In order to investigate new materials for metal cutting applications, cubic boron nitride, cutting tools with different amounts of binder phase were sintered in HPHT toroid type apparatus under 7.7 GPa and in temperature range of 1450-2450°C. Initial mixtures of three composition were chosen with 50, 60, 65 vol. % of cBN, 5 vol. % of Al was added to mixture to prevent oxidation. Phase composition,
The incidence of multiple myeloma is characterized by a steep increase with advancing age. Dramatic improvements in survival have been reported in clinical trials; however, elderly patients are generally underrepresented in these. The aims of this study are to review patterns of incidence and survival in multiple myeloma in the general population. We searched PubMed for population-based studies on
Background: Type 2 diabetes (T2D) and poor mental health are two major public health concerns in Europe. Ethnicity is identified as a risk marker for both conditions. Middle-Eastern immigrants represent the largest group of non-European immigrants in Sweden and are at increased risk for T2D. In clinical trials, lifestyle interventions focusing on physical activity and healthy diet have been shown
Artikeln behandlar översiktigt arkitektur, porträttkonst, makt och historiebruk från Gustav Vasa till drottning Kristina. I den görs också utvikningar som relaterar den svenska utvecklingen inom området till den på kontinenten. En sammanfattning av övergången från medeltid till renässans till i Sverige ingår liksom en utblick på vad som sker inom arkitekturen i Skåne som vid tiden var danskt, samt
Using South African Families (SAF), a new database of settler genealogies, we provide the first comprehensive analysis of women’s cohort fertility in settler South Africa between 1700 and 1900. We find parity rates of approximately seven children per woman until a decline begins starting with women born in the 1850s. We date the start of South Africa’s fertility transition to cohorts born in the 1
This paper studies the effects of improvements in infant health produced by the introduction of sulphapyridine in the late-1930s as treatment against pneumonia on outcomes in adulthood. Based on longitudinal individual data for the whole population of Sweden 1968–2012 and archival data on the availability of sulphapyridine and applying a difference-in-differences approach, it finds that mitigation
Metabolic syndrome (MetS) is a consequence of obesity and defined as cluster of at least three out of five criteria covering insulin resistance/glucose intolerance, abdominal obesity, hypertension, low HDL-c and elevated TG levels. Imbalance between energy intake and expenditure is known to alter normal physiological function in many aspects, and leads to obesity, which in the long run may turn in
Objectives - To explore the longitudinal stability of measures of cognition during treatment with acetylcholinesterase inhibitors (AchEI) in patients with Alzheimer's disease (AD). Materials and methods -Cognitive status was measured in a cohort of 60 patients at 6 months after initiation of treatment with AchEI (baseline) and after an additional 6 months of treatment (endpoint). A Quick Test of C
Anti-neutrophil cytoplasmic antibodies (ANCAs) have a pathogenic role in ANCA-associated vasculitis. The origin of ANCAs and anti-glomerular basement membrane (GBM) antibodies, however, is unknown. In this study, we determined whether natural autoantibodies against myeloperoxidase (MPO), proteinase 3 (PR3), and GBM were present in each of 10 healthy Chinese and Swedish individuals, negative for al
Popular Abstract in Swedish Sammanfattning Varför ungdomar använder tobak är en stor och komplex fråga. Det finns faktorer på samhälls-, grupp- och individnivå som påverkar unga. Omgiv-ningens normer och attityder liksom föräldrars och kompisars tobaksvanor har betydelse och påverkar ungdomar att börja använda tobak eller att avstå. För att motverka tobaksbruk krävs en kombination av åtgärder på Why adolescents are using tobacco is a large and complex issue. There are factors on society, group and individual levels that affect the youngsters. The norms and attitudes in their surrounding, as well as the tobacco habits of parents and friends, are important when it comes to affecting adolescents to start using tobacco or abstain from it. Counteracting the use of tobacco requires a combinatio
Purpose The purpose of this study is to better understand online anonymity in the global file-sharing community in the context of social norms and copyright law. The study describes the respondents in terms of use of Virtual Private Networks (VPNs) or similar services with respect to age, gender, geographical location, as well as analysing the correlation with file-sharing frequencies. Design/me
Context: Low testosterone (T) has been associated with incident metabolic syndrome (MetS), but it remains unclear if this association is independent of sex hormone binding globulin (SHBG). Estradiol (E2) may also be associated with MetS, but few studies have investigated this. Objective: To study the association between baseline sex steroids and the development of incident MetS and to investigate
OBJECTIVE: The goal of this study was to investigate whether on-topic visual cues can serve as aids for the maintenance of discourse coherence and informativeness in autobiographical narratives of persons with Alzheimer's disease (AD). METHODS: The experiment consisted of three randomized conversation conditions: one without prompts, showing a blank computer screen; an on-topic condition, showing
Background: Quadrupole moments of excited nuclear states are important observables for geometrically interpreting nuclear structure in terms of deformed shapes, although data are scarce and sometimes ambiguous, in particular, in neutron-rich nuclides. Purpose: A measurement was performed for determining the spectroscopic quadrupole moment of the 2(1)(+) state of Ba-140 in order to clarify the char
