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Nowadays, there is a tendency towards higher dynamics in markets and increasing competition especially in engineering and high tech industries. Firms today need to invent new products, acquire unique business models and thereby continuously exceed customer expectations as well as outperform competition. In contrast to the previous innovative approach that relied solely on internal capabilities, ma
The common agricultural policy (CAP) has been stated as one of the most important policies within the European Union (EU), and is the fundament for agricultural development in the member states. However, the CAP has been stated to effect biodiversity in a negative way. To handle the decreasing biodiversity in agricultural landscapes within the EU, the CAP has been developed to include measures to
Physical education could play an important role in promoting future physical activity, but do students perceive the physical education content to be relevant for their personal and future goals? And does this affect their in-class motivation? The aim of this study was to investigate the role of perceived relevance of physical education course content in relation to students‘ contextual self-determ
A lowered mineral density in the skeletal bones may indicate osteoporosis and an increased risk of fragility fractures. However, lower bone mass does not reveal the whole truth about the status of the bone quality. This thesis investigated the microstructure and mechanical properties of 14 trabecular bone plugs in order to get a comprehensive understanding of how the trabecular network changes fro
Slow sand filters (SSF) are biofilters which utilize the metabolic potential of complex biofilms to remove contaminants, such as harmful chemicals, organic carbon and pathogenic bacteria, from drinking water. This study presents the first analysis of fungal internally transcribed spacer (ITS) sequences in samples from two newly constructed and one established SSF, all of which underwent a removal
Having spent so many of my free hours immersed in the worlds of translated fiction, I set out to create a research project designed to better understand the entanglements of the imagination behind this art. This thesis aims to explore how literary translators construct their identity and how multiple forces create instability in the professional self. It continues to dissect how these identities b
Triple Helix theory is to analyze the function and interactions of academia, industry and government in regional innovation systems. The cases of Silicon Valley, Boston, Cambridge and Scania in Sweden all provide empirical studies for understanding the effects of the triple helix model in improvement of absorption ability and industrial clusters. But some scholars also argue that the Triple Helix
This paper empirically investigates the determinants of climate change perceptions across Europe, focusing on how political orientation and human values affect attribution- and trend belief, perceived impacts of climate change and climate concern. Previous studies in this field of research have ignored the risk of reverse causality, which is addressed in this paper by conducting the epidemiologica
Oxygenases use molecular oxygen to oxidise a plethora of biologically important reactions. To gain access to these reactions on a synthetic, and in the longer run, an industrial scale research focused on mimicking the active oxidant species, synthesis and reactivity studies of high valent Fe(IV)-oxo complexes that function as mimics of the active sites in iron oxygenases has been performed in the
OBJECTIVE: To identify how the gp130-signaling cytokine oncostatin M (OSM), acting alone or in concert with IL-1beta or TNFalpha, affects synovial fibroblast expression of genes relevant to inflammation and bone erosion in inflammatory arthritis. METHODS: Synovial fibroblasts (SFs) were isolated from non-arthritic wild type (WT) or OSM receptor deficient (OSMR(-/-)) mice and stimulated with OSM, I
Background: The Patient Enablement Instrument (PEI), which has been used to evaluate core ingredients in primary care consultations, has been proposed as a means of moving beyond patient satisfaction evaluations. The aim of the present study was to examine the reliability and applicability of the PEI to the Swedish context. Methods: The original PEI was translated to Swedish and included in a ques
Introduction: Bipolar disorder is characterized by severe mood symptoms including major depressive and manic episodes. During manic episodes, many patients show cognitive dysfunction. Dopamine and glutamate are important for cognitive processing, thus the COMT and DAOA genes that modulate the expression of these neurotransmitters are of interest for studies of cognitive function. Methodology: Focu
Background: Pain is a common condition among prehospital patients. The present study is designed to determine whether adding low-dose ketamine as additional analgesia improves the pain/nausea scores and hemodynamic parameters compared to morphine sulphate alone among patients with bone fractures. Methods: Prospective, prehospital clinical cohort study. Twenty-seven patients were included with acut
Assessment of the potential impact of climate change on water systems has been an essential part of hydrological research over the last couple of decades. However, the notion that such assessments should also include technological, demographic and land use changes is relatively recent. In this study, the potential impacts of climate change and continued urbanisation on waste and stormwater flows i
CYLD is a tumour-suppressor gene that is mutated in a benign skin tumour syndrome called cylindromatosis. The CYLD gene product is a deubiquitinating enzyme that was shown to regulate cell proliferation, cell survival and inflammatory responses, mainly through inhibiting NF-kappa B signalling. Here we show that CYLD controls cell growth and division at the G(1)/S-phase as well as cytokinesis by as
The demand for rare earth elements (REEs) is growing, while the future supply is uncertain. Their unique electronic characteristics make them irreplaceable, and the commercial value of pure fractions is high. A model-based simulation study is presented that compares batch chromatography with the twin-column MCSGP (multicolumn countercurrent solvent gradient purification) process for ion-exchange c
