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Progress with respect to enrichment and separation of native membrane components in complex lipid environments, such as native cell membranes, has so far been very limited. The reason for the slow progress can be related to the lack of efficient means to generate continuous and laterally fluid supported lipid bilayers (SLBs) made from real cell membranes. We show in this work how the edge of a hyd
By using a microfabricated nerve chip with integrated electrodes through which peripheral nerves can generate and make electrical connects, it should be possible to control a remote prosthesis by processing the detected nerve signals. In this study different artificial neural networks have been employed for classification of such complex patterns of signals. The signals were obtained from four ele
BACKGROUND: Among asymptomatic patients with severe carotid artery stenosis but no recent stroke or transient cerebral ischaemia, either carotid artery stenting (CAS) or carotid endarterectomy (CEA) can restore patency and reduce long-term stroke risks. However, from recent national registry data, each option causes about 1% procedural risk of disabling stroke or death. Comparison of their long-te
Background/Aim: Signs of hypoxic ischaemic encephalopathy (HIE) on head computed tomography (CT) predicts poor neurological outcome after cardiac arrest. We explore whether levels of brain injury markers in blood could predict the likelihood of HIE on CT. Methods: Retrospective analysis of CT performed at 24–168 h post cardiac arrest on clinical indication within the Target Temperature Management
PURPOSE: To document and analyse the decision to withhold or withdraw life-sustaining treatment (LST) in a population of very old patients admitted to the ICU.METHODS: This prospective study included intensive care patients aged ≥ 80 years in 309 ICUs from 21 European countries with 30-day mortality follow-up.RESULTS: LST limitation was identified in 1356/5021 (27.2%) of patients: 15% had a withho
Objective- The Wnt/β-catenin pathway orchestrates development of the blood-brain barrier, but the downstream mechanisms involved at different developmental windows and in different central nervous system (CNS) tissues have remained elusive. Approach and Results- Here, we create a new mouse model allowing spatiotemporal investigations of Wnt/β-catenin signaling by induced overexpression of Axin1, a
MRI-based biophysical models are typically validated by comparison to ex-vivo histology of fixed tissue. The fixation process itself and the accompanied autolysis processes strongly modify tissue composition, and lead to MR signal changes, making the validation of biophysical models for in vivo MRI particularly challenging. To better understand the temporal evolution of the fixation process within
The newly described immunoglobulin G-binding streptococcal surface protein, protein G, was used to prepare and characterize rabbit antibodies. The antibodies were directed against rat hormone-sensitive lipase, the rate-limiting enzyme in the hydrolysis of the triacylglycerols stored in adipose tissue. Antiserum was obtained after two injections with 20 micrograms enzyme protein, and the immunoglob
Synovial sarcoma (SyS) is an aggressive soft-tissue malignancy that is characterised by a pathognomonic t(X;18)(p11.2;q11.2) translocation, which produces the fusion oncogene named SS18::SSX. Despite recent advancements in our understanding of synovial sarcoma biology, the cell-of-origin remains undefined. A mesenchymal stromal cell (MSC) specific CreERT2 line was employed to express SS18::SSX in
Efficient management of on-demand delivery systems is essential for modern urban logistics, especially in densely populated cities with complex spatial layouts. This study introduces a novel, computer-supported cooperative framework that utilizes Infomap-based hierarchical community detection to analyze spatial multilevel clustering patterns. The experiment was conducted to large scale on-demand d
To generate the required antiproton beam intensity for the FAIR PANDA experiment, a dedicated proton LINAC (pLINAC) for the FAIR accelerator chain is being constructed. Klystron modulators are power converters within the high-power RF system of the pLINAC. Here, seven modulator systems with a nominal pulse power amplitude of 115 kV / 54 A, an effective pulse width of 360 µs and a pulse repetition
Psykosociala faktorers samband med PMS undersöktes genom en webbaserad enkätundersökning som besvarades av 1320 svensktalande kvinnor och transpersoner med aktiv menscykel. Studien visade samband mellan höga nivåer av PMS och att bo tillsammans med barn eller partner samt att ha en mindre stöttande partner och låg relationstillfredställelse. Personer med en låg utbildningsnivå, egna erfarenheter aThe association between PMS and psychosocial factors was studied using the responses of 1320 women and transgender people with an active menstrual cycle to a Swedish web-based survey. Living with children or a romantic partner was associated with higher levels of PMS, in addition to low relational satisfaction and a less supportive partner. Premenstrual Coping, Perfectionism and Silencing the Self
The discourse on beauty has primarily been focused on the white gaze to prescribe its normative standards. The white gaze conceptualizes the way in which beauty is dwelled on within society: the foisting of Caucasian-looking beauty canons on black women, and the veneration of whiteness as superior. Black bodies are vanguards, either being desired or erased. In literature, the expression “white gaz
A housewife of many trades: applying history of knowledge to the rationalization of the home in 1946–1956. After World War II, Swedish women were expected to return to their work at home, due to a shortfall of work for men. However, to make housework more attractive for women, its status needed to increase. One way to make housework more appealing for women was to rationalize the home and therefo
Denna uppsats bygger på forskning inom den komplexa juridiska situationen bakom EU’s externa agerande och konflikten mellan externa och interna juridiska spörsmål inom områden med delad kompetens inom Unionen. EU’s lagstiftning, genom sin egen struktur, har en unik position inom hierarkin för rättskällor. Av de i uppsatsen presenterade rättsfallen och dokumentationen i övrigt kan man utläsa att deThis thesis is based on research into the area of the complex legal situation behind EU’s external affairs with the conflict between external and internal legal matters in regards to the area of shared competences within the Union. EU legislation, by its own structure, has a unique position in the hierarchy of laws. As can be seen by case law and documentation presented here it also contains its o
Värdepappershandel tillsammans med annan finansiell verksamhet har undantagits från mervärdesskatteplikt inom EU sedan 1977, när Direktivet 77/388/EEC lagstiftades. Ursprungligen stadgades undantaget för dessa finansiella tjänster på grund av skattetekniska problem som uppkommer vid framställande av det beskattningsbara underlaget. Direktivet, som sedermera har ersatts av Direktivet 2006/112/EC (tTrade in securities along with other financial activities has been enjoying the VAT exempt status within the EU since 1977, when Directive 77/388/EEC was passed. The VAT exemption for the financial services was originally enacted due to the difficulties relating to defining the taxable amount for the VAT purposes. The mentioned Directive, which has consequently been replaced by Directive 2006/112/
To reduce traffic accidents caused by driver factors, realizing technology to monitor and preemptively respond to the state of a driver is necessary. In this study, drivers' electroencephalogram (EEG) data during driving were acquired, and the effect of carelessness warnings was analyzed. The frequency of carelessness per minute was low for the case of presence of warnings. The originality of this
