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Sensorimotor relationship and musical affordances

Recent years has seen a number of music researchers taking interest in the concept of affordances. Although interpretation of the concept varies, a common denominator is that affordances are opportunities for actions emerging between a subject and the environment. As such, it is an analytical perspective that highlights material and embodied dynamics of musical practice, dimensions central to musi

18 F-FDG-PET/CT in breast cancer imaging : Restaging and Implications for treatment decisions in a clinical practice setting

Background and purpose: Although the diagnostic accuracy of 18F-fluorodeoxyglucose – positron emission tomography/computed tomography (18F-FDG-PET/CT) for breast cancer (BC) has been well studied, few studies have evaluated the impact of 18F-FDG-PET/CT on BC patient care. This study aimed to investigate restaging and 18F-FDG-PET/CT-induced changes in clinical decision-making in patients with BC. M

Prediction of adverse maternal and perinatal outcomes associated with pre-eclampsia and hypertensive disorders of pregnancy : a systematic review and meta-analysis

Background: Hypertensive disorders of pregnancy are a leading cause of maternal and perinatal morbidity and mortality. If women at high risk for developing complications could be identified early, level of care could be triaged, limited resources could be correctly allocated and targeted interventions to prevent complications could be implemented. Methods: We updated a systematic review and meta-a

B Cells and Tertiary Lymphoid Structures : Friends or Foes in Cancer Immunotherapy?

Tumor cells pose a challenge to the adaptive immune system, and its key cell types, T and B cells, have frequently been associated with an improved prognosis. The success of immune checkpoint blockade has confirmed the relevance of T cells. However, the role of B cells is increasingly recognized, and highlighted in this review. Recent data suggest that tumors contain a diverse set of B cells refle

Patterns of Persistence : Intergenerational mobility and Sweden's social structure 1865-2015

In all times, societies have known social hierarchies and boundaries between individuals and groups with distinct social characteristics. The extent to which such hierarchies and boundaries are consequential for life outcomes and persist over time differs between societies. These changes over generations in the social structure, and the social, economical, and institutional developments that shape

WONCA Europe position statement on the redefinition of fatty liver disease

Family doctors and general practitioners (GPs) are the frontline in the management of fatty liver disease. With its high prevalence and strong association with other conditions commonly treated in primary care, the voice of family doctors and GPs has an important role in informing the discussion on the redefinition of fatty liver disease. Primary care uptake of any proposed name will be hampered i

Interventional and EBUS cytology in Sweden

Interventional cytology was first introduced in Sweden in the late 1940ies by Sixten Franzén at the Karolinska University Hospital in Solna, Stockholm. In the early 1950ies, Nils Söderström started using the technique at the University Hospital in Lund. Cytology was successively established as common practice at the pathology departments in Sweden, and e.g. Solna and Lund today have a high rate of

EXPLORING THE NEXUS BETWEEN ORGANIZATIONAL ANTICIPATION AND ADAPTATION IN CRISIS MANAGEMENT

Organizational anticipation involves the ability to foresee and analyze potential threats and disturbances as a means to minimize the likelihood of hazard occurrence and to reduce the potential impacts. Common methods include Risk and Vulnerability Assessments (RVAs) and contingency planning, where potentially harmful events are identified and analyzed, and where measures to prevent, respond to an

Anastomotic leak following oesophagectomy : research priorities from an international Delphi consensus study

BACKGROUND: The Oesophago-Gastric Anastomosis Audit (OGAA) is an international collaborative group set up to study anastomotic leak outcomes after oesophagectomy for cancer. This Delphi study aimed to prioritize future research areas of unmet clinical need in RCTs to reduce anastomotic leaks.METHODS: A modified Delphi process was overseen by the OGAA committee, national leads, and engaged clinicia

The Evolution of Benchmarking through Municipal Benchmarking Networks - An Evaluation of a National Benchmarking project in Swedish Municipalities?

In order to stimulate benchmarking and comparisons between different municipal activities, the Swedish Association of Local Authorities and Regions (SALAR) and the Ministry of Finance in the year of 2007 initiated a voluntary nationwide Swedish benchmarking project (NBP) in order to develop new measures that capture the relationship between cost and quality. The ambition is that the new measures s

Re-organising the logistics resources of companies after mergers and acquisitions

This paper discusses the relation between logistics and Mergers and Acquisitions (M&A) of companies within the same industry and same industry level (i.e. horizontal M&A). The purpose is to study the effects of M&A on the logistics resources of companies and the possibility for companies to benefit from the re-organising of these resources in the form of synergies. The study hopes to a

Throat related symptoms and voice : development of an instrument for self assessment of throat-problems

BACKGROUND: Symptoms from throat (sensation of globus; frequent throat clearing; irritated throat) are common in patients referred to voice clinics and to ENT specialists. The relation to symptoms of voice discomfort is unclear and in some cases patients do not have voice problems at all. Instruments for patients' self-reporting of symptoms, and assessment of handicap, such as the Voice Handicap I

NLK-mediated phosphorylation of HDAC1 negatively regulates Wnt signaling

The Wnt signaling pathway is essential in regulating various cellular processes. Different mechanisms of inhibition for Wnt signaling have been proposed. Besides β-catenin degradation through the proteasome, nemo-like kinase (NLK) is another molecule that is known to negatively regulate Wnt signaling. However, the mechanism by which NLK mediates the inhibition of Wnt signaling was not known. In th

Effect of entrainment on liquid film dryout in vertical upward annular flow

This work aims to investigate the effect of liquid entrainment on liquid film dryout in annular flow for flow boiling. Entrainment and deposition rates of droplets were included in mass conservation equations to estimate the local liquid film mass flux in annular flow, and the critical vapor quality at dryout conditions. Different entrainment rate correlations were evaluated using flow boiling dat

Fast iterative retrieval algorithm for ultrashort pulse characterization using dispersion scans

We present an iterative retrieval algorithm based on data constraint for ultrashort pulse characterization using dispersion scan (d-scan). The proposed algorithm is much faster and leads to a drastic reduction of retrieval times, but, compared to the standard algorithm, it performs less robustly in the retrieval of noisy d-scan traces. The algorithm is tested on several simulated cases and in two

SOX9 is a major negative regulator of cartilage vascularization, bone marrow formation and endochondral ossification

SOX9 is a transcription factor of the SRY family that regulates sex determination, cartilage development and numerous other developmental events. In the foetal growth plate, Sox9 is highly expressed in chondrocytes of the proliferating and prehypertrophic zone but declines abruptly in the hypertrophic zone, suggesting that Sox9 downregulation in hypertrophic chondrocytes might be a necessary step

Convergence Analysis of the Dirichlet-Neumann Iteration for Finite Element Discretizations

We analyze the convergence rate of the Dirichlet-Neumann iteration for the fully discretized unsteady transmission problem. Specifically, we consider the coupling of two linear heat equations on two identical non overlapping domains with jumps in the material coefficients across these. In this context, we derive the iteration matrix of the coupled problem. In the 1D case, the spectral radius of th

Planar laser-induced fluorescence of HCO for instantaneous flame front imaging in hydrocarbon flames

The detection of the formyl radical (HCO) is of great interest in the field of combustion research since it can provide information about the local heat release (HR) rate which is a key parameter in the understanding of combustion processes. Unfortunately, due to the low signal level, HCO planar laser-induced fluorescence (PLTF) has so far not been applicable for single-shot imaging, which is nece