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Solving nonlinear systems inside implicit time integration schemes for unsteady viscous flows

We considered nonlinear solvers inside implicit time integration schemes for the time dependent compressible Navier-Stokes equations. The existing solvers turn out to be adequate, but amenable to significant improvements. Regarding multigrid schemes, we demonstrated that reoptimizing a multigrid scheme for the case of a time dependent equation leads to significant improvements in convergence speed

Radiation Spectra of 200 MeV Electrons in Diamond and Silicon Crystals at Axial and Planar Orientations

Results of the first experiment on studying the radiation spectra of electrons with energy 192 7 MeV in diamond and silicon crystals at axial and plane orientation performed at the MAX-lab facility were presented. At these orientation the particle's motion can be both regular, when axial and planar channeling are possible, and chaotic, when the coherent electron interaction with single strings rev

A sustainable working life for all ages – The swAge-model

The demographic shift is fast becoming a global challenge and an important public health concern. The proportion of people over 65 years is currently 10% around the world, but it is expected to rise to 22% by the year 2050 [1]. Populations ageing rapidly is widely seen as one of the most powerful transformative forces affecting society over the next four decades [1–4]. The ageing population is pro

Stellar abundance of binary stars : Their role in determining the formation location of super-earths and ice giants

Binary stars form from the same parent molecular cloud and thus have the same chemical composition. Forming planets take building material (solids) away from the surrounding protoplanetary disc. Assuming that the disc's accretion on to the star is the main process that clears the disc, the atmosphere of the star will show abundance reductions caused by the material accreted by the forming planet(s

User privacy attitudes regarding proximity sensing

User attitudes on privacy with respect to location data has been extensively studied. However, user attitudes of privacy in relation to proximity sensing is still lacking. We present the results from a survey conducted on users of a proximity sensing application we developed and diffused by handing out phones with the proximity sensing application pre-installed, with 31 respondents. The results co

Electroweak phase transitions in multi-Higgs models : The case of Trinification-inspired THDSM

The rich vacuum structure of multi-Higgs extensions of the Standard Model (SM) may have interesting cosmological implications for the electroweak phase transition (EWPT). As an important example of such class of models, we consider a particularly simple low-energy SM-like limit of a recently proposed Grand-Unified Trinification model with the scalar sector composed of two Higgs doublets and a comp

Hermann Heller on Politics : Discipline, Sphere and Activity

Most students of politics are familiar with Carl Schmitt’s definition of politics as a friend-enemy distinction. Yet, only few know of alternative conceptions of politics in interwar Germany that emphasize cooperation and legality over confrontation and decisionism. To unlock such views, this article examines the work of Hermann Heller, a social-democratic constitutional theorist, and takes a clos

An experimental and kinetic modeling study on nitric oxide formation in premixed C3 alcohols flames

This study provides new quantitative NO concentrations measurements in n-propanol + air and i-propanol + air flames together with a new combustion kinetic model. The heat flux method was employed to stabilize propyl alcohols flames and the initial gas conditions were set to 323 K, 1 atm, and ϕ=0.7-1.4. Saturated laser-induced fluorescence was employed to measure NO concentration in the post-combus

Vaccination Strategies and Immune Modulation of Atherosclerosis

Adaptive as well as innate immune responses contribute to the development of atherosclerosis. Studies performed in experimental animals have revealed that some of these immune responses are protective while others contribute to the progression of disease. These observations suggest that it may be possible to develop novel therapies for cardiovascular disease by selectively modulating such atheropr

A Self-Learning Methodology for Epileptic Seizure Detection with Minimally-Supervised Edge Labeling

Epilepsy is one of the most common neurological disorders and affects over 65 million people worldwide. Despite the continuing advances in anti-epileptic treatments, one third of the epilepsy patients live with drug resistant seizures. Besides, the mortality rate among epileptic patients is 2 - 3 times higher than in the matching group of the general population. Wearable devices offer a promising

Culturing patient-derived malignant hematopoietic stem cells in engineered and fully humanized 3D niches

Human malignant hematopoietic stem and progenitor cells (HSPCs) reside in bone marrow (BM) niches, which remain challenging to explore due to limited in vivo accessibility and constraints with humanized animal models. Several in vitro systems have been established to culture patient-derived HSPCs in specific microenvironments, but they do not fully recapitulate the complex features of native bone

Rash during lamotrigine treatment is not always drug hypersensitivity a retrospective cohort study among children and adults

Purpose Cutaneous adverse drug reactions (cADRs) are a major cause of lamotrigine (LTG) discontinuation. Remarkable variation in their reported incidence suggests confounders and diverse terms and definitions. The aim of this study was to identify immunological cADRs and to throw light on classification and differential diagnoses in children and adults. Methods Hospital records of 2683 patients wi

Naturally acquired antibodies against Plasmodium falciparum : Friend or foe?

Antibodies are central to acquired immunity against malaria. Plasmodium falciparum elicits antibody responses against many of its protein components, but there is also formation of antibodies against different parts of the red blood cells, in which the parasites spend most of their time. In the absence of a decisive intervention such as a vaccine, people living in malaria endemic regions largely d

Effect modification of ambient particle mortality by radon: A time series analysis in 108 U.S. cities

Numerous studies have reported a positive association between ambient fine particles and daily mortality, but little is known about the particle properties or environmental factors that may contribute to these effects. This study assessed potential modification of radon on PM2.5 (particulate matter with an aerodynamic diameter <2.5 ?m)-associated daily mortality in 108 U.S. cities using a two-stag