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Conclusion : Studying candidates, parties and voters. Lessons learned and new questions

In the concluding chapter, we outline the major findings from the eleven book chapters by connecting them to one another. We come back to the triadic delegation and accountability relationship between candidates, voters and parties that were developed based on principal–agent theory, and emphasise the most relevant findings of this book that inform this triad. The chapter also takes a critical sta

An Exact Ewald Summation Method in Theory and Practice

We present the widespread Ewald summation method in a new light by utilizing a truncated Gaussian screening charge distribution. This choice entails an exact formalism, also as particle mesh Ewald, which in practice is not always the case when using a Gaussian screening function. The presented approach reduces the number of dependent parameters compared to a Gaussian and, for an infinite reciproca

B-1 Cells Carry the Memory of Neonatal Immune Imprinting

Group A Streptococcus is a common pathogen that elicits a protective humoral response against the cell wall component GlcNAc. In this issue of Immunity, New et al. demonstrate the ability of long-lived B-1 cells to be programmed by microbial colonization and early life immunization to uniquely incorporate GlcNAc reactivity in mice, establishing their critical role in mediating neonatal immune impr

Alterations of particle deposition in the respiratory tract at increasing activity

The deposited dose of particles in the respiratory tract is an important factor for understanding health effects of aerosol particles. It is a combination of the exposure, volume of inhaled air and particle deposition. At increasing activity the minute ventilation ( volume of breath x number of breaths ) increase . Little is known about if and how this affects the regional particle deposition.

The Explicit Body: Feminist Performance as Sex Education

In 1990 the performance artist, porn star, photographer and sex workers’ rights activist Annie Sprinkle presented her Post Post Porn Modernist: Still in Search of the Ultimate Sexual Experience. This show included the section “Public Cervix Announcement” (PCA) in which Sprinkle presented the audience with two large, oval shaped, colored drawings: one a cartoonish rendering of the female reproducti

Multiple functions of the new cytokine-based antimicrobial peptide thymic stromal lymphopoietin (TSLP)

Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine, hitherto mostly known to be involved in inflammatory responses and immunoregulation. The human tslp gene gives rise to two transcription and translation variants: a long form (lfTSLP) that is induced by inflammation, and a short, constitutively-expressed form (sfTSLP), that appears to be downregulated by inflammation. The TSLP forms ca

Atmospheric circulation patterns associated with the variability of River Ammer floods : Evidence from observed and proxy data

The relationship between the frequency of River Ammer floods (southern Germany) and atmospheric circulation variability is investigated based on observational Ammer River discharge data back to 1926 and a flood layer time series from varved sediments of the downstream Lake Ammer for the pre-instrumental period back to 1766. A composite analysis reveals that, at synoptic timescales, observed River