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Mergers of Authorities in Central Government: Role Ambiguities and Blame-Avoidance

Mergers of autonomous executive authorities in central government have become increasingly common, in particular in the Nordic countries. As compared to private sector mergers, the role of the principal (the central Government and its ministries) is more obscure in these mergers, this chapter argues. When problems arise in a merger, the ministry can take a step back and shift to a stakeholder posi

The language of eating and drinking: a window on Orang Asli meaning-making

We make in this chapter a first probe into the lexical domain of eating and drinking as it is construed in the Aslian languages, a branch of the Austroasiatic language family spoken by a majority of the Orang Asli of the Malay Peninsula. Fundamental to human experience and representation, the domain of ingestion has received increased linguistic attention in recent years. Setting out from our own

Concurrent Engineering in Machinery

Application of concurrent engineering (CE) to machinery has to consider the type of production (individual, serial), product complexity and level of design. Product development (PD) involves four characteristic levels of design that requires specific activities. The characteristic design levels require definitions of the activities for providing the necessary software and other support for all pha

A haploid genetic screen identifies the G1/S regulatory machinery as a determinant of Wee1 inhibitor sensitivity

The Wee1 cell cycle checkpoint kinase prevents premature mitotic entry by inhibiting cyclin-dependent kinases. Chemical inhibitors of Wee1 are currently being tested clinically as targeted anticancer drugs. Wee1 inhibition is thought to be preferentially cytotoxic in p53-defective cancer cells. However, TP53 mutant cancers do not respond consistently to Wee1 inhibitor treatment, indicating the exi

On the effects of Streptococcal NAD+-glycohydrolase and Streptolysin O on macrophages

SummaryThe human pathogen Streptococcus pyogenes (GAS) causes both superficial infections, such as strep throat, and invasive infections, such as necrotizing fasciitis, and is responsible for about half a million deaths each year. The number of GAS infections have increased since the 1980’s, due to the emergence of a M1T1 strain that has become widely disseminated. Increased expression of Streptol

Social class, economic capital and the Swedish, German and Danish asylum systems

Refugees have moved into the spotlight of public debate in Europe and North America, where they are targeted by multiple welfare state interventions. This volume analyses the tensions that emerge within the strong welfare states of Northern Europe when faced with an increased immigration of protection-seeking people. Examining the encounter between refugees and the welfare states, this book explor

Prognostication after cardiac arrest : Results of an international, multi-professional survey

Aim: We explored preferences for prognostic test performance characteristics and error tolerance in decisions regarding withdrawal or continuation of life-sustaining therapy (LST) after cardiac arrest in a diverse cohort of medical providers. Methodology: We distributed a survey through professional societies and research networks. We asked demographic characteristics, preferences for prognostic t

It's in The Mix: Configuring Industrial Cool

In recent decades, a transformation of traditional industries has taken place in large parts of the Western world, involving a number of interesting combination processes. One manifestation of Industrial Cool may be referred to as 'recycled factories', whereby different types of cultural institutions have established themselves in industrial premises and touched up the aesthetics of a former indus