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In chapter 33, Hallonsten argues that the change in the historical context of Big Science, from the Cold War to contemporary innovation driven economies, has transformed its character and raised anew the issue of its legitimization. According to Hallonsten, the promotion of Big Science projects, as a result of their uncertain epistemic and technological payoff, often entails 'overselling' marketin
Quantum annealing has shown promise for finding solutions to difficult optimization problems, including protein folding. Recently, we used the D-Wave Advantage quantum annealer to explore the folding problem in a coarse-grained lattice model, the HP model, in which amino acids are classified into two broad groups: hydrophobic (H) and polar (P). Using a set of 22 HP sequences with up to 64 amino ac
Aim: To explore the impact of age on the discriminative ability of the National Early Warning Score (NEWS) 2 in prediction of unanticipated Intensive Care Unit (ICU) admission, in-hospital cardiac arrest (IHCA) and mortality within 24 hours of Rapid Response Team (RRT) review. Furthermore, to investigate 30- and 90-day mortality, and the discriminative ability of NEWS 2 in prediction of long-term
Smoluchowski's coagulation equation is studied for the kernel K (u, v) = E(u(alpha)v(beta) + u(beta) v(alpha)) with real, non-negative alpha, beta and E, using gamma distributions with a singularity at zero volume as initial size spectra. As the distribution parameter of the gamma distribution, p, approaches its lower limit (p -> 0) the distribution becomes similar to pv(p-1) 1 for small v. Asympt
BACKGROUND: Increased pulmonary vascular resistance is frequently seen after lung transplantation. Thromboxane A2 is a potent vasoconstrictor of pulmonary arteries. Thromboxane-elicited vasoconstriction can ben counteracted by prostacyclin. The effects of lung transplantation on the biosynthesis of these substances were investigated. METHODS: Pulmonary artery flush perfusion with a low-potassium d
Hereditary cystatin C amyloid angiopathy is a dominantly inherited disorder, characterized by dementia, paralysis, and death from cerebral hemorrhage in early adult life. A variant of the cysteine proteinase inhibitor, cystatin C, is deposited as amyloid in the tissues of the patients and their spinal-fluid level of cystatin C is abnormally low. The disease-associated Leu-68-->Gln mutant (L68Q) cy
Children and adolescents exposed to traumatic events are at high risk of developing posttraumatic stress disorder (PTSD). With the rare exception of very young children, their PTSD presentations at the symptom level are similar to those of trauma-exposed adults, as are their patterns of psychiatric comorbidity, particularly for adolescents. Untreated, at least a significant proportion will carry o
This entry offers a short description of basic research questions, different theories, and topics in lexical semantic research. At the beginning, it states five fundamental questions that all lexical semantics theories need to attend to in descriptions and explanations of their observations and findings. A brief presentation of past and present theoretical approaches on lexical semantics follows,
Shared housing is a rather unusual phenomenon in Sweden. However, due to the decreasing availability of affordable housing and a large share of single-person households in urban areas, sharing is on the rise and new forms of shared housing have entered the market. By analysing how shared housing overlaps with existing patterns of socioeconomic segregation and by interviewing developers of diverse
During times of crisis, such as the COVID-19 pandemic, policymakers and the public reveal a strong preference for fairness in pricing even when that would reduce efficiency. For example, they support the application of price gouging laws that prevent prices for necessities from skyrocketing but probably also dampen incentives for firms to produce more and alleviate the shortage. More generally, a
Emmer (1993) claimed creativity to be a bridge between art and mathematics exemplified (www. olats.org/colloque/textes/texte7.shtml) in his traveling exhibition The Eye of Horus: Art and Mathematics (Emmer, 1990). A shared language is needed to make bridges between science, art and metaphysics (Thiessen, 1998). Scientific phenomena and concepts need to be possible to isolate for better understandi
Drawing on ethnographic observations in Sweden and affect theory, this study immerses researcher-consumer bodies in extended retail spaces to explore affective encounters. Conceptualizing consumption spaces as affective assemblages, it unveils how affective states of disposition, disorientation, and distress from interactions with socio-material elements shape bodily experiences of inclusion and e
