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Social norms play a fundamental role in holding groups together. The rationale behind most of them is to coordinate individual actions into a beneficial societal outcome. However, there are cases where pro-social behavior within a community seems, to the contrary, to cause inefficiencies and suboptimal collective outcomes. An explanation for this is that individuals in a society are of different t
Research infrastructures play a key role in launching a new generation of integrated long-Term, geographically distributed observation programmes designed to monitor climate change, better understand its impacts on global ecosystems, and evaluate possible mitigation and adaptation strategies. The pan-European Integrated Carbon Observation System combines carbon and greenhouse gas (GHG; CO2, CH4, N
The importance of semi-arid ecosystems in the global carbon cycle as sinks for CO 2 emissions has recently been highlighted. Africa is a carbon sink and nearly half its area comprises arid and semi-arid ecosystems. However, there are uncertainties regarding CO 2 fluxes for semi-arid ecosystems in Africa, particularly savannas and dry tropical woodlands. In order to improve on existing remote-se
Biogeochemical models use meteorological forcing data derived with different approaches(e.g. based on interpolation or reanalysis of observation data or a hybrid hereof) to simulateecosystem processes such as gross primary productivity (GPP). This study assesses theimpact of different widely used climate datasets on simulated gross primary productivity andevaluates the suitability of them for repr
Objectives: To explore associations between carer burden and characteristics of (1) the informal carer, (2) the person with dementia, and (3) the care support network in 8 European countries. Design: Cross-sectional study. Setting: People with dementia judged at risk of admission to long-term care (LTC) facilities in 8 European countries (Estonia, Finland, France, Germany, Netherlands, Spain, Swed
The important role of fire in regulating vegetation community composition and contributions to emissions of greenhouse gases and aerosols make it a critical component of dynamic global vegetation models and Earth system models. Over 2 decades of development, a wide variety of model structures and mechanisms have been designed and incorporated into global fire models, which have been linked to diff
Temperature is a key constraint on ecosystem respiration but is typically measured at only one or a few points across a study site. Given the exponential relationship between temperature and respiration, small differences in temperature across a heterogeneous ecosystem may result in large differences in respiration fluxes. These differences are not captured in current respiration models which use
The majority of the world’s peatlands are located in northern regions where climate change is occurring most rapidly. Therefore, there is an urgent need to understand whether, and under what conditions, peatlands will remain carbon sinks or become carbon sources. The uncertainties in our predictions stem from a variety of sources, including uncertainty about the competing effects of rising air tem
The boreal biome exchanges large amounts of carbon (C) and greenhouse gases (GHGs) with the atmosphere and thus significantly affects the global climate. A managed boreal landscape consists of various sinks and sources of carbon dioxide (CO2), methane (CH4), and dissolved organic and inorganic carbon (DOC and DIC) across forests, mires, lakes, and streams. Due to the spatial heterogeneity, large u
Africa has been undergoing significant changes in climate and vegetation in recent decades, and continued changes may be expected over this century. Vegetation cover and composition impose important influences on the regional climate in Africa. Climate-driven changes in vegetation structure and the distribution of forests versus savannah and grassland may feed back to climate via shifts in the sur
In this study, a global vegetation model (LPJ-GUESS) is forced with spatial information (Nomenclature of Units for Territorial Statistics (NUTS) 2 level) of land-use intensity change in the form of nitrogen (N) fertilization derived from a model chain which informed the Common Agricultural Policy Regionalized Impact (CAPRI) model. We analysed the combined role of climate change and land-use intens
Aim/hypothesis: Human enteroviral infections are suggested to be associated with type 1 diabetes. However, the mechanism by which enteroviruses can trigger disease remains unknown. The present study aims to investigate the impact of enterovirus on autophagy, a cellular process that regulates beta cell homeostasis, using the clonal beta cell line INS(832/13) and human islet cells as in vitro models
Identification of prostate gold fiducial markers in magnetic resonance imaging (MRI) images is challenging when CT images are not available, due to misclassifications from intra-prostatic calcifications. It is also a time consuming task and automated identification methods have been suggested as an improvement for both objectives. Multi-echo gradient echo (MEGRE) images have been utilized for manu
Fire frequency is changing globally and is projected to affect the global carbon cycle and climate. However, uncertainty about how ecosystems respond to decadal changes in fire frequency makes it difficult to predict the effects of altered fire regimes on the carbon cycle; for instance, we do not fully understand the long-term effects of fire on soil carbon and nutrient storage, or whether fire-dr
Background--The relationship between "on-treatment" low platelet reactivity and longitudinal risks of major bleeding dual antiplatelet therapy following acute coronary syndromes remains uncertain, especially for patients who do not undergo percutaneous coronary intervention. Methods and Results--We analyzed 2428medicallymanaged acute coronary syndromes patients fromthe Targeted Platelet Inhibition
It is established that the glomerular filter sieves macromolecules based on their size, shape, and charge. Anionic proteins are thus retarded compared with their neutral or cationic counterparts. However, recent studies have indicated that charge effects are small, or even "anomalous," for polysaccharides. We therefore investigated the impact of charge on the glomerular permeability to polysacchar
Global warming is driving environmental change in the Arctic. However, our current understanding of this change varies strongly among different environmental disciplines and is limited by the number and distribution of field sampling locations. Here, we use a quantitative framework based on multivariate statistical modeling to present the current state of sampling across environmental disciplines
Purpose: Guidelines recommend targeting mean arterial pressure (MAP) > 65 mmHg in patients after cardiac arrest (CA). Recent trials have studied the effects of targeting a higher MAP as compared to a lower MAP after CA. We performed a systematic review and individual patient data meta-analysis to investigate the effects of higher versus lower MAP targets on patient outcome. Method: We searched the
Boreal forest ecosystems are predicted to experience more frequent summer droughts due to climate change, posing a threat to future forest health and carbon sequestration. Forestry is a regionally dominant land use where the managed secondary forests are typically even-aged forests with low structural and tree species diversity. It is not well known if managed secondary forests and unmanaged prima
