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Fusion genes are potent driver mutations in cancer. In this study, we delineate the fusion gene landscape in a consecutive series of 195 paediatric B-cell precursor acute lymphoblastic leukaemia (BCP ALL). Using RNA sequencing, we find in-frame fusion genes in 127 (65%) cases, including 27 novel fusions. We describe a subtype characterized by recurrent IGH-DUX4 or ERG-DUX4 fusions, representing 4%

High entropy alloys (HEA) containing Al and Cr have been observed to manifestimpressive dry air oxidation resistance. But the testing temperature attempted inthe previous works has been restricted up to 1050ºC. In the present work AlxCoCrFeNi HEAs (x=0,0.3,0.6,1 mole) synthesized by arc melting route have beensubjected to rigorous dry air oxidation test up to 1150ºC. The as cast HEAs withx=0 and x

Toxin-antitoxins (TAs) are prokaryotic two-gene systems composed of a toxin neutralized by an antitoxin. Toxin-antitoxin-chaperone (TAC) systems additionally include a SecB-like chaperone that stabilizes the antitoxin by recognizing its chaperone addiction (ChAD) element. TACs mediate antiphage defense, but the mechanisms of viral sensing and restriction are unexplored. We identify two Escherichia

In early breast cancer, a preoperative core-needle biopsy (CNB) is vital to confirm the malignancy of suspected lesions and for assessing the expression of treatment predictive and prognostic biomarkers in the tumor to choose the optimal treatments, emphasizing the importance of obtaining reliable results when biomarker status is assessed on a CNB specimen. This study aims to determine the concord

Over the past years, eosinophils have become a focus of scientific interest, especially in the context of their recently uncovered functions (e.g. antiviral, anti-inflammatory, regulatory). These versatile cells display both beneficial and detrimental activities under various physiological and pathological conditions. Eosinophils are involved in the pathogenesis of many diseases which can be class

This biennial Review summarizes much of Particle Physics Using data from previous editions, plus 2205 new measurements from 667 papers, we list, evaluate, and average measured properties of gauge bosons, leptons, quarks, mesons, and baryons We also summarize searches for hypothetical particles such as Higgs bosons, heavy neutrinos, and supersymmetric particles All the particle properties and searc

The PHENIX tracking system consists of Drift Chambers (DC), Pad Chambers (PC) and the Time Expansion Chamber (TEC). PC1/DC and PC2/TEC/PC3 form the inner and outer tracking units, respectively. These units link the track segments that transverse the RICH and extend to the EMCal. The DC measures charged particle trajectories in the r-phi direction to determine P-T of the particles and the invariant

Background--Atherosclerosis is an inflammatory lipid disorder and the main underlying pathology of acute ischemic events. Despite a vast amount of data from murine atherosclerosis models, evidence of B-cell involvement in human atherosclerotic disease is limited. We therefore investigated the association of circulating B-cell subtypes with the occurrence of secondary cardiovascular events in advan

Ovaj članak prezentira teoretski i metodološki model za analizu prepričanih iskustava bivših logoraša koji su kao civili odvedeni u koncentracione logore početkom rata u Bosni i Hercegovini 1990-tih godina. Cilj je analizirati prepričane rituale ratnog nasilja u koncentracionim logorima kao i identifikovati kako se počinioci ratnog nasilja i žrtve simbolično definiraju u pričama. Priče o nasilju u

Aims: The TTM2-trial is a multi-centre randomised clinical trial where targeted temperature management (TTM) at 33 °C will be compared with normothermia and early treatment of fever (≥37.8 °C) after Out-of-Hospital Cardiac Arrest (OHCA). This paper presents the design and rationale of the TTM2-trial follow-up, where information on secondary and exploratory outcomes will be collected. We also prese

Randomised controlled trials are increasingly conducted as embedded, nested, or using cohorts or routinely collected data, including registries, electronic health records, and administrative databases, to assess if participants are eligible for the trial and to facilitate recruitment, to deliver an embedded intervention, to collect trial outcome data, or a combination of these purposes. This repor

BackgroundThe Clinical Frailty Scale (CFS) is frequently used to measure frailty in critically ill adults. There is wide variation in the approach to analysing the relationship between the CFS score and mortality after admission to the ICU. This study aimed to evaluate the influence of modelling approach on the association between the CFS score and short-term mortality and quantify the prognostic

Introduction: Immune checkpoint inhibitors (ICIs) have transformed lung cancer treatment, yet their effectiveness seem restricted to certain patient subsets. Current clinical stratification on the basis of programmed death ligand 1 (PD-L1) expression offers limited predictive value. Given the mechanism of action, directly detecting spatial programmed cell death protein 1 (PD1)–PD-L1 interactions m

Microsoft Word - Lunds universitets exportkontrollprogram_STYR2020_2073_tillg Sida 1 av 22 Rektor BESLUT Diarienummer STYR 2020/2073 Datum 2021-10-21 Lunds universitets exportkontrollprogram – efterlevnadsprogram för produkter med dubbla användningsområden Fastställt av rektor 2021-10-21. Postadress Box 117 Besöksadress Sandgatan 5 Telefon 046-222 69 29, 046-222 00 00 E-post robert.collin@bygg.lu.

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2021-12/Lunds-universitets-exportkontrollprogram-efterlevnadsprogram-for-produkter-med-dubbla-anvandningsomraden.pdf - 2026-05-14

Civilingenjörsutbildning i datateknik utbildningsplan Sida 1 av 7 Utbildningsplan Civilingenjörsutbildning i datateknik Master of Science in Engineering, Computer Science and Engineering - Fakultet: Lunds tekniska högskola, LTH - Programkod: TADAT - Omfattning: 300 högskolepoäng - Tillträdesnivå: Grundnivå - Examensnivå: Avancerad nivå - Beslutsfattare: Programledning C/D - Beslutsdatum: 2026-02-1

https://www.student.lth.se/fileadmin/lth/student/Utbildningsplaner_2023_och_fram/Grund_svenska/26_27/Utbildningsplan_Civilingenjoersutbildning_i_datateknik_26-27.pdf - 2026-05-14

Civilingenjörsutbildning i lantmäteri utbildningsplan Sida 1 av 7 Utbildningsplan Civilingenjörsutbildning i lantmäteri Master of Science in Engineering, Surveying and Land Management - Fakultet: Lunds tekniska högskola, LTH - Programkod: TALAN - Omfattning: 300 högskolepoäng - Tillträdesnivå: Grundnivå - Examensnivå: Avancerad nivå - Beslutsfattare: Programledning L - Beslutsdatum: 2026-02-20 - U

https://www.student.lth.se/fileadmin/lth/student/Utbildningsplaner_2023_och_fram/Grund_svenska/26_27/Utbildningsplan_Civilingenjoersutbildning_i_lantmaeteri_26-27.pdf - 2026-05-14

Centre for Mathematical Sciences Faculty of Science Centre for Mathematical Sciences Division of Mathematics and Numerical Analysis Course Analysis for MATP32 Harmonic Analysis, Autumn 2022 Course Information Lecturer: Eskil Rydhe Teaching assistants: Number of students: 11 newly registered and 0 re-registered. 4 students answered the course evaluation, 3 of them are enrolled on the Master’s Progr

https://www.maths.lu.se/fileadmin/maths/Matematik_NF/Kursutvaerderingar/HT2022/MATP32HT22.pdf - 2026-05-14

Centre for Mathemat ica l Sc iences Div is ion of Mathemat ics and Numerica l Analys is Course Analysis for MATM20 Mathematical Modelling, VT 2022 Course Information Lecturer: Joachim Hein Teaching assistants: None Number of students: 15 14 newly registered and 1 re-registered. 3 students answered the course evaluation, 2 of them are enrolled on the Bachelor’s programme in Mathematics and 1 of the

https://www.maths.lu.se/fileadmin/maths/Matematik_NF/Kursutvaerderingar/VT2022/MATM20VT22.pdf - 2026-05-14

Kursutvärdering Kurs: Matematisk statistik:MASA02 Utvärderas ocks̊a p̊a LTH: Nej Lärare:: Dragi Anevski Antal studenter: 37 Svarsfrekvens: 10/37 Sammanfattning: Kursen fick lite blandad kritik. Det fanns bland annat kommentarer kring organisationen av övningar och labbar. Kommentarer: Åtgärder till nästa g̊ang: Vi kommer att se över kursslitteratur samt övningar och labbar till nästa g̊a

https://www.maths.lu.se/fileadmin/maths/utbildning_education/KU_Matematisk_statistik_MASA02_HT21.pdf - 2026-05-14

Microsoft Word - HILMA 2009-11-11.doc HILMA Historiska Institutionen i Lund Meddelar Att… Årgång 35, 2009/10, Nr 5, 2009-11-11 Underlagen till HILMA förvaras i pärmar som står i rum 209, på hyllan ovanför faxen. Där hittar du ytterligare information om seminarier, anställningsvillkor, stipendier och annat samt ansök- ningsblanketter i förekommande fall. De sistnämnda, som är samlade i en separat p

https://www.hist.lu.se/fileadmin/_migrated/content_uploads/hilma_ht09_5_03.pdf - 2026-05-14