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In 2005 the Swedish Association of the Pharmaceutical Industry (LIF) initiated a national environmental classification and information system for pharmaceuticals. This investigation reports the results from a survey, conducted among the persons involved in the start-up process. The aim of this study is to generate knowledge contributing to the clarification of the motivations, expectations, and in

An increasingly competitive market, as well as transforming consumer expectations, have considerably altered the socio-economic landscape in which contemporary profit-making organizations operate. As a result, it is more difficult than ever to establish a successful and distinct brand, whilst adhering to fast-changing customer demands – especially when consumers bank on brands to fulfil a higher p

AimsWe aimed to investigate the association between the exercise systolic blood pressure (SBP) response and future hypertension (HTN) in normotensive individuals referred for cycle ergometry, with special regard to reference exercise SBP values and exercise capacity.Methods and resultsIn this longitudinal cohort study, data from 14 428 exercise tests were cross-linked with Swedish national registr

Vad består materia av? Det är en fundamental fråga som mänskligheten försökt besvara i tusentals år. Vårt svar på den frågan har utvecklats enormt de senaste 200 åren. Atomer, från grekiskans ord för odelbar, bygger upp materian vi ser omkring oss. Det antogs längeatt atomer verkligen var odelbara, men strax innan sekelskiftet år 1900, kom experimentellt bevis från J. J. Thomson, som påvisade att The papers in this thesis all concern the treatment of colors in perturbative QCD, both in the context of hard scattering cross sections and for parton showers. The complexity of the color structure of QCD increases quickly with the number of external partons. One way of tackling this issue is by using an orthogonal, group theory based, type of bases, called multiplet bases. This is the topic of p

Recent studies highlight the importance of lipotoxic damage in aortic cells as the major pathogenetic contributor to atherosclerotic disease. Since the STE20-type kinase STK25 has been shown to exacerbate ectopic lipid storage and associated cell injury in several metabolic organs, we here investigate its role in the main cell types of vasculature. We depleted STK25 by small interfering RNA in hum

The bone marrow microenvironment provides indispensable factors to sustain blood production throughout life. It is also a hotspot for the progression of hematologic disorders and the most frequent site of solid tumor metastasis. Preclinical research relies on xenograft mouse models, but these models preclude the human-specific functional interactions of stem cells with their bone marrow microenvir

Legal persons have traditionally been understood as entities with legal rights and/or duties. This traditional concept of legal personhood has been challenged during the last decades: In legal practice through the global development in law where previous legal non-persons such as different non-human natural entities, non-human animals, fetuses and artificial intelligences have been ascribed, or be

Gas turbine systems are predominantly designed to be fuelled with gaseous fuels within a limited Wobbe index range (typically HHV=45-55 MJ/Nm3 or 1200-1480 Btu/scf). When low calorific fuel gases are fired, the engine will be forced to operate outside its design envelope. The added mass flow will typically raise the cycle pressure ratio and in two-shaft designs also raise the gas generator shaft s

In this work we present an integrated system for whole chromosome analysis of single bacterium. Using whole genome barcoding techniques, which offer direct and rapid microscopic visualization of the entire genome in one field-of-view, we aim to rapidly identify individual bacterium. We are developing our device to achieve the crucial, and difficult process of isolating a bacterium, removing the DN

Gas turbine systems are predominantly designed to be fuelled with gaseous fuels within a limited Wobbe index range (typically HHV=45-55 MJ/Nm3 or 1200-1480 Btu/scf). When low calorific fuel gases are fired, the engine will be forced to operate outside its design envelope. The added mass flow will typically raise the cycle pressure ratio and in two-shaft designs also raise the gas generator shaft s

The evolution of char porous structure can affect the gasification rate of biomass char. A model based on the classical capillary pores is developed taking into account different conversion rates for pores having different radii. The contribution of different pores with different radii is taken into account using an effectiveness factor presented for each pore radius. As the char conversion procee

The DEK gene is highly expressed in a wide range of cancer cells, and a recurrent translocation partner in acute myeloid leukemia. While DEK has been identified as one of the most abundant proteins in human chromatin, its function and binding properties are not fully understood.

Banverket äger och förvaltar ett stort antal tunnlar samtidigt som planering och byggande pågår för ett flertal tunnlar. Syftet med föreliggande arbete är att öka kunskapen och på sikt förbättra och förenkla processen angående personsäkerhet i tunnlar. Rapporten beskriver det inventeringsarbete som utförts med avseende på både befintliga och nya tunnlar med fokus på personsäkerhet...

The underpinning idea of extended producer responsibility rules has been to provide incentives for manufacturers to design products that are easy to recycle. However, current incentives for design for recycling are limited, due to the problems in assigning costs for collection and recycling of individual products to the relevant producers. An alternative way to promote design for recycling, or to

This article examines the modern concept of literary value. Since the late 18th century, the problem of literary value has been regarded, from the point of view of the so called double discourse of value, as a presupposed opposition between material and spiritual ”economies”. Many Romanticist and Modernist authors believe that literature – and in a broader sense art and aesthetics – constitute a v