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The parameters affecting the lipase activity and operational lifetime during chemo-enzymatic epoxidation of fatty acids were investigated. Immobilized Candida antarctica lipase B (Novozym (R) 435) was incubated in the presence of various reaction components (i.e. toluene, water, H2O2, oleic acid, perpalmitic acid, and epoxystearic acid, respectively) at temperatures between 20 and 60 degrees C fol

Purpose: Emotional Intelligence (EI) has been widely discussed within business performance, but not as much in the context of branding. This paper argues that the use of EI permeates a successful brand building process towards increased brand equity and a stronger brand. Hence, the purpose is to investigate the role of EI in branding, by identifying capabilities of EI in the brand building process

Financial return series are often characterized by volatility clusters and a leptokurtic distribution. Many models that account for these properties exist, with the GARCH model proposed by Bollerslev (1986) being the most popular. This thesis explores an alternative model to capture the stochastic volatility in financial time series. The considered model is denoted the autoregressive gamma varianc

Sustainability science has to solve some of the most complex problems of our times. So far, the field of sustainability science is more known for its promises than its solutions. It is successful at creating knowledge but is lacking in terms of developing actionable knowledge. The transdisciplinary process incorporates practitioners and the people for whom the solution is intended in the research

There is a consensus within both academia and politics on the important role of cities in achieving a more sustainable world, however, many scholars emphasise that the implementation of sustainable cities is often unsuccessful. The planning process from sustainability visions to actual implementation in an urban context is not straightforward or linear, and discursive struggles influence the proce

We study how processing states alternate during information search tasks. Inference is carried out with a discriminative hidden Markov model (dHMM) learned from eye movement data, measured in an experiment consisting of three task types: (i) simple word search, (ii) finding a sentence that answers a question and (iii) choosing a subjectively most interesting title from a list of ten titles. The re

Enriching the surface density of immobilized capture antibodies enhances the detection signal of antibody sandwich microarrays. In this study, we improved the detection sensitivity of our previously developed P-Si (porous silicon) antibody microarray by optimizing concentrations of the capturing antibody. We investigated immunoassays using a P-Si microarray at three different capture antibody (PSA

Popular Abstract in Swedish Avhandlingens huvudsyfte är att försöka utreda hur man kommer till förståelse av det historiska huset och att diskutera vilken roll den historiska dokumentationen spelar i restaureringsprojekteringen. I restaurering som i allt annat arbete med arkitektur är förståelse ett nyckelord. Förståelse för de särskilda förutsättningar som ligger i uppgiften, i objektet, i skapanThe principal aim of the thesis is to evaluate the significance of the documentation of a building’s history for the work of restoring it and caring for it. Thus it may be said to address restoration as a hermeneutical problem, besides considering the relationships between the work of documentation; analyses of the resulting data; and the creative process in which the ideology of restoration is im

A major component of aircraft noise is the jet noise created by the high velocity hot stream exhausting from a jet engine, interacting with itself and with the surrounding cold air. In the present paper the flow and acoustic fields that are generated by two coaxial jets are considered. Numerically, the problem is divided into a flow related part (Navier-Stokes system of equation) and an acoustic p

This thesis explores different models of random graphs. The first part treats a change from the preferential attachment model where the network incorporates new vertices and attach them preferentially to the previous vertices with a large number of connections. We introduce on top of this model the deletion of the oldest connections in the system and discuss the impact on the degree of the vertice

Thesis purpose: This thesis will through a case study of a recently rebranded bank “Jyske Bank”, seek to research deeper within the field of service sector rebranding. The internal communication used in connection to the rebranding, will be analyzed in order to investigate what initiatives Jyske Bank’s organizational leaders launched to implement the rebranding and furthermore whether the initiati

Problemformulering: Hur ser informationsflödet mellan leverantör och entreprenör ut och vilka icke värdeskapande aktiviteter finns idag kopplade till en bristfällig leveransplanering? Kan dessa aktiviteter reduceras med befintligt systemet eller finns önskemål att ändra eller ta fram en helt annan typ av system? Syfte: Att ge läsaren en god inblick i hur det arbetars med materialförsörjning på enProblem: This study examines problems in the Construction supply chain. Most industries have already included use of assistive technology in their daily work and I will research if it is possible to implement a system for delivery planning in the construction industry to reduce non-value adding activities. A system designed for construction delivery planning has been developed. In order to grow an

Background: Although case-control studies have identified numerous single nucleotide polymorphisms (SNPs) associated with prostate cancer, the clinical role of these SNPs remains unclear. Objective: Evaluate previously identified SNPs for association with prostate cancer and accuracy in predicting prostate cancer in a large prospective population-based cohort of unscreened men. Design, setting, an

Chronic myeloid leukemia (CML) stem cells appear resistant to tyrosine kinase inhibitors (TKIs) in vitro, but their impact and drug sensitivity in vivo has not been systematically assessed. We prospectively analyzed the proportion of Philadelphia chromosome-positive leukemic stem cells (LSCs, Ph+CD34+CD38=) and progenitor cells (LPCs, Ph+CD34+CD38+) from 46 newly diagnosed CML patients both at the

MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally regulate gene expression. There have been several reports of miRNA deregulation in prostate cancer and the biological evidence for an involvement of miRNAs in prostate tumorigenesis is increasing. In this study, we show that miR-34c is downregulated in prostate cancer (p = 0.0005) by performing qRT-PCR on 49 TURPs from prosta

Diamond-Blackfan anemia (DBA) is a congenital erythroid hypoplasia caused by haploinsufficiency of genes encoding ribosomal proteins (RPs). Perturbed ribosome biogenesis in DBA has been shown to induce a p53-mediated ribosomal stress response. However, the mechanisms of p53 activation and its relevance for the erythroid defect remain elusive. Previous studies have indicated that activation of p53

The transcription factor STAT3 is constitutively active in several malignancies including castration-resistant prostate cancer and has been identified as a promising therapeutic target. The fungal metabolite galiellalactone, a STAT3 signaling inhibitor, inhibits the growth, both in vitro and in vivo, of prostate cancer cells expressing active STAT3 and induces apoptosis of prostate cancer stem cel

Cyclodextrin glycosyltransferases (CGTases) from Paenibacillus macerans, Thermoanaerobacter sp. ATCC 53627, Bacillus stearothermophilus and a Carboxydocella sp. (phylogenetically identified from genomic DNA) were characterized with respect to their catalytic activity in different reactions, with emphasis on reactions useful for the elongation of the carbohydrate group of alkyl glycosides. All CGTa

Variation in transcription factor 7-like 2 (TCF7L2), the strongest genetic risk factor for type 2 diabetes (T2D), may play a role in prostate cancer (PCa) depending on lifestyle factors. The aims of this study were to determine if TCF7L2 rs7903146 is associated with risk of PCa and if the association is modified by lifestyle factors independently of T2D status.