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Human iPS cell-derived dopaminergic neurons function in a primate Parkinson’s disease model 5 9 2 | N A T U R E | V O L 5 4 8 | 3 1 A U g U s T 2 0 1 7 LETTER doi:10.1038/nature23664 Human iPS cell-derived dopaminergic neurons function in a primate Parkinson’s disease model Tetsuhiro Kikuchi1, Asuka Morizane1, Daisuke Doi1, Hiroaki Magotani1, Hirotaka Onoe2, Takuya Hayashi2, Hiroshi Mizuma2, sayuk

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_nature_0.pdf - 2026-05-04

Kursguide - Course Syllabus • • • • Fastställande Kursplanen är fastställd av Naturvetenskapliga fakultetens utbildningsnämnd 2007- 03-01 att gälla från och med 2007-07-01, höstterminen 2007. Allmänna uppgifter Kursen är en valbar kurs på avancerad nivå och ges inom programmen för masterexamen i naturgeografi och ekosystemanalys, masterexamen i atmosfärsvetenskap och biogeokemiska kretslopp samt m

https://www.nateko.lu.se/sv/sites/nateko.lu.se.sv/files/ngen01_kursplan.pdf - 2026-05-04

Minnesanteckningar från EDS Nordic User Group, Stockholm 2013-10-10 Plats: Stockholms universitetsbibliotek När: 2013-10-10 kl. 10-16 Närvarande: Egon Nilsson (Högskolan i Gävle, biblioteket), Mikael Arvidsson (Karlstad universitetsbibliotek), Mikael Blad (Karolinska universitetssjukhuset/Stockholms läns landsting), Jonas Barck (Linnéuniversitets bibliotek), Emma Nolin (Lunds universitetsbibliotek

https://www.ub.lu.se/sites/ub.lu.se/files/minnesanteckningar_fran_eds_nordic_user_group.pdf - 2026-05-04

This dissertation is about bridging the gap between strategy and operations in organizations. To bridge that gap, processes are viewed not only from an operational perspective but also from conceptual, as well as a hierarchical perspectives. Bridging the gap can furthermore make organizational change initiatives more logical, and simplify the development and usage of needed performance measurement

The E4SD (Energy for Sustainable Development) Online Course is a joint initiative led by the International Institute for Industrial Environmental Economics (IIIEE) at Lund University, Sweden with the United Nations Development Programme (UNDP), the United Nations Environment Programme (UNEP), and the Global Network on Energy for Sustainable Development (GNESD) as partners. The overall objective of

Erythropoiesis is intimately coupled to cell division, and deletion of the cell cycle regulator retinoblastoma protein (pRb) causes anemia in mice. Erythroid-specific deletion of pRb has been found to result in inefficient erythropoiesis because of deregulated coordination of cell cycle exit and mitochondrial biogenesis. However, the pathophysiology remains to be fully described, and further chara

Despite the recent success of tyrosine kinase inhibitors (TKIs) in the treatment of chronic myeloid leukemia (CML), approximately 2-17% of patients develop clonal cytogenetic changes in the Philadelphia-negative (Ph(-)) cell population. A fraction of these patients, in particular those displaying trisomy 8 or monosomy 7, are at risk of developing a myelodysplastic syndrome (MDS) or acute myeloid l

History shows that companies that survive in a severe competitive climate are those that are highly adaptable to market and technological changes. Product development is one of the key activities that assure company survival by renewal of its offer to its customers. A scientific formalism has to be created to fulfill two purposes: 1) to ensure that the design and development of a product is succes

The number of patients affected by Alzheimer's disease among the population is currently growing, while the availability of resources for their assistance is decreasing. A solution for this problem is provided by the use of Ambient Assisted Living technologies, with the objectives to prolong the independent living of patients at home, to relieve assistance burden on caregivers, and to improve care

Altered DNA methylation is often seen in malignant cells, potentially contributing to carcinogenesis by suppressing gene expression. We hypothesized that heritable methylation potential might be a risk factor for breast cancer and evaluated possible association with breast cancer for single nucleotide polymorphisms (SNPs) either involving CpG sequences in extended 5'- regulatory regions of candida

Objective: To investigate the effectiveness of a culturally adapted lifestyle intervention for changing dietary intake, particularly energy, fat and fibre intakes, in the intervention group (IG) compared with the control group (CG). Design: Randomised controlled trial. Setting: IG (n 50) and CG (n 46). The IG was offered seven group sessions, including one cooking class, over a period of 4 months.

Recent emission legislation in the marine sector has emphasized the need to reduce nitrogen oxides (NOx) emissions as well as sulphur emissions. The fulfilment of emission legislation limits with conventional marine diesel oil (MDO) requires complex and expensive aftertreatment systems and in this framework lean burn pilot ignited dual fuel (diesel and natural gas) is revealed as one of the most s

The frequent mounting and dismounting the tractor required by many farming operations increases the risk of falls, particularly for older farmers. The present study explored the risk factors related to tractor ingress and egress in older farmers from two countries with a different tradition in terms of safety culture: Sweden and Italy. Eighteen male farmers aged 65 + (8 from Skåne region, southern

This paper analyzes various innovation strategies of firms. Using five waves of the Community Innovation Survey in Sweden, we have traced the innovative behavior of firms over a 10-year period, i.e. between 2002 and 2012. We distinguish between sixteen innovation strategies, which compose of Schumpeterian four types of innovations (process, product, marketing, and organizational) plus various comb

The Gaussian wave model has been successfully used in ocean engineering for more than half a century. It is well understood, and there exists both exact theory and efficient numerical algorithms for calculation of the distribution of safety related wave characteristics, such as crest height and steepness. Its drawback is its lack of realism: it produces waves which are stochastically symmetric, bo

The aim of this study was to compare the performance of the enzymes produced by Trichoderma reesei Rut C30 and the good extracellular beta-glucosidase-producing mutant Trichoderma atroviride TUB F-1663 to that of commercial preparations in the enzymatic hydrolysis and the simultaneous saccharification and fermentation (SSF) of steam-pretreated spruce (SPS). The concentrated TUB F-1663 enzyme was f

Whereas the characterization of B lymphoid progenitors has been facilitated by the identification of lineage-and stage-specific surface markers, the continued identification of differentially expressed proteins increases our capacity to explore normal and malignant B cell development. To identify novel surface markers with stage-specific expression patterns, we explored the reactivity of CD19+ B c

The aim of this study was to examine what factors experienced psychotherapists emphasize as central and change developing in psychotherapy. The intention was to highlight the therapists' personal thoughts and experiences of psychotherapeutic change. By personal interviews with three cognitive and three psychodynamic psychotherapists, data was retrieved and then analysed with a qualitative phen

As one of the main objectives of the Bologna process, employability has become a central concept to consider for universities when designing higher education. Although the universities are required implementing employability, there is no defined meaning of what employability actually is which implies a significant autonomy for university teachers in how to interpret the concept and fill it with me