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In this thesis, we apply Bayesian Optimization to estimate the parameters of the LPJ-GUESS dynamic vegetation model with a focus on Methane (CH4) emissions in the Siikaneva wetland in Finland. Previous research has used other statistical methods, such as Markov Chain Monte Carlo (MCMC), to estimate the LPJ-GUESS model parameters, achieving a root mean square error (RMSE) of 0.023. Our objective is

Tillsammans med klimatförändringar och omfattande överfiske utgör IUU-fiske (olagligt, orapporterat och oreglerat fiske) ett allvarligt hot mot den marina biodiversiteten globalt. En särskilt drabbad region är Västafrika, där kuststater historiskt har haft rikliga fiskeresurser inom sina exklusiva ekonomiska zoner (EEZ) i Atlanten. Den ökande förekomsten av industriellt fiske, till stor del represExacerbated by climate change and general overfishing, illegal, unreported, and unregulated (IUU) fishing poses a serious threat to marine biodiversity globally. One particularly affected region is West Africa, where coastal States have historically possessed abundant fishing resources within their Exclusive Economic Zones (EEZs) in the Atlantic Ocean. The reliance on industrial-scale fishing, lar

This book is particularly concerned with examining the creation of the Öresund region, a process that represents the internationalization and geopolitical changes in the world, where new industrial regions emerge in competition for growth and wealth. The emerging Öresund region is a new type of industrial region – a transnational region that is difficult to analyze in a traditional way, for examp

The aim of this short paper is to present an ongoing joint research project, Human Factors in Air Navigation Services (HUFA), between the Swedish Civil Aviation Administration and Lund University. Results from the study will only be given very briefly. The project focuses on human and organizational factors and safety in air traffic control.

This literature survey aims at representing the current research on the cognitive aspects of the design activity, with an emphasis on problem-solving processes. The study is based on the selection of about sixty papers and books on the subject. The principal parameters of the study were defined as follows: general topics of the works, objects of the works, cognitive approaches, research results, s

Large eddy simulations are performed for a single- and multiphase jets in crossflow (JICF). The multiphase JICF are compared to the single-phase case for the same momentum and mass flow ratios but with droplets of different sizes. Multiphase JICF have stronger counter-rotating vortex pairs (CVPs) than a corresponding single-phase JICF. Moreover, their trajectories are higher and their induced wake

Objective: To examine the performance of ultrasound (US) for the diagnosis of gout using the presence of monosodium urate monohydrate (MSU) crystals as the gold standard. Methods: We analyzed data from the Study for Updated Gout Classification Criteria (SUGAR), a large, multicenter observational cross-sectional study of consecutive subjects with at least 1 swollen joint who conceivably may have go

Transcriptome-wide association studies (TWAS) are powerful tools for identifying gene-level associations by integrating genome-wide association studies and gene expression data. However, most TWAS methods focus on linear associations between genes and traits, ignoring the complex nonlinear relationships that may be present in biological systems. To address this limitation, we propose a novel frame

A central challenge in linguistics pertains to understanding how the polished, static form of a written text emerges from the messy, moment-by-moment decisions of the writer. While the structures of finished texts have been extensively theorized, and the real-time cognitive processes of writing have been widely studied, the relationship between these real-time processes and the functional linguist

Övergången till en hållbar textilindustri, såsom textilåtervinning, kräver förbättrade metoder för hantering av färgämnen. För närvarande finns inga generella, industriellt implementerade processer som avlägsnar färgämnen utan att skada dem, och examensarbetet undersöker detta tillsammans med Rewin Textiles AB. Företaget återvinner polyester genom depolymerisering och därför utvärderas implementerThe transition towards sustainable textile approaches, such as textile recycling, requires im-proved methods for handling dyes. Currently, no real industrially implemented processes exist that remove dyes without damaging them and this thesis investigates this issue together with Rewin Textiles AB. This company recycles polyester through depolymerisation and therefore, the implementation of a pre-

Denna studie tar sin utgångspunkt i en tid då den kreativa sektorn genomgår omfattande förändringar, där generativ AI utmanar föreställningen om mänsklig kreativitet som något unikt och oersättligt. Genom en fallstudie av den AI-genererade bandet The Velvet Sundown undersöks huruvida publiken kan utveckla parasociala relationer till karaktärer som saknar biologisk existens, eller om dessa relation

Miljömålsberedningens (MMB) betänkande kommer vid en viktig tid, när tiden blir alltmer knapp för att sträva efter beslutade nationella och internationella mål om klimat och biologisk mångfald. De närmaste åren är på många sätt kritiska för att dels begränsa klimatpåverkan, dels värna om natur och biologisk mångfald i linje med vetenskapen och beslutade ambitionsnivåer. Det är mycket viktigt med å

The multiphase micro-structured devices such as microchannels have been recently taken into consideration to replace the conventional equipment in different applications. The mass transfer coefficients and the interfacial area in the multiphase microchannels are much larger than those in the conventional equipment. This paper reviews the experimental studies on mass transfer in gas-liquid and liqu

In advective-dispersive simulations of aquifers, retardation factors using linear adsorption isotherms are commonly employed to represent the adsorption-desorption process for solutes in soil. In particular, the retardation factors that use entire pore space (total porosity) or effective pore space (effective porosity) are widely used. Although another retardation factor that describes solute tran

With the increasing global demand for precise and efficient pharmaceuticals and the biopharma industry moving towards Industry 4.0, the need for advanced process integration, automation, and modeling has increased as well. In this work, a method for automatic modeling and calibration of an integrated preparative chromatographic system for pharmaceutical development and production is presented. Bas

Activating signaling mutations are common in acute leukemia with KMT2A (previously MLL) rearrangements (KMT2A-R). These mutations are often subclonal and their biological impact remains unclear. Using a retroviral acute myeloid mouse leukemia model, we demonstrate that FLT3 ITD, FLT3 N676K, and NRAS G12D accelerate KMT2A-MLLT3 leukemia onset. Further, also subclonal FLT3 N676K mutations accelerate