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Hint of an exocomet transit in the CHEOPS light curve of HD 172555
HD 172555 is a young (∼20 Myr) A7V star surrounded by a 10 au wide debris disk suspected to be replenished partly by collisions between large planetesimals. Small evaporating transiting bodies, that is exocomets, have also been detected in this system by spectroscopy. After β Pictoris, this is another example of a system possibly witnessing a phase of the heavy bombardment of planetesimals. In suc
Effects of hypoxia on bronchial and alveolar epithelial cells linked to pathogenesis in chronic lung disorders
Introduction: Chronic lung disorders involve pathological alterations in the lung tissue with hypoxia as a consequence. Hypoxia may influence the release of inflammatory mediators and growth factors including vascular endothelial growth factor (VEGF) and prostaglandin (PG)E 2. The aim of this work was to investigate how hypoxia affects human lung epithelial cells in combination with profibrotic s
Rethinking IS Strategic Alignment : A Middle Management Perspective
IS strategic alignment remains a research phenomenon of key interest, specifically regarding the dimensions of social IS alignment (i.e., shared IS understanding among key organizational members) and intellectual IS alignment (i.e., IS/business strategy congruence). The examination of IS alignment has been predominantly limited to the examination of top ranks within the organization; however, we c
A genomic mutational constraint map using variation in 76,156 human genomes
Analysis of plasma metabolomes from 11 309 subjects in five population-based cohorts
Plasma metabolomics holds potential for precision medicine, but limited information is available to compare the performance of such methods across multiple cohorts. We compared plasma metabolite profiles after an overnight fast in 11,309 participants of five population-based Swedish cohorts (50–80 years, 52% women). Metabolite profiles were uniformly generated at a core laboratory (Metabolon Inc.)
Hierarchical build-up of bio-based nanofibrous materials with tunable metal–organic framework biofunctionality
Multifunctional, light-weight, responsive materials show promise in a range of applications including soft robotics, therapeutic delivery, advanced diagnostics and charge storage. This paper presents a novel, scalable, efficient and sustainable approach for the preparation of cellulose nanofibril-based aerogels via a facile ice-templating, solvent exchange and air-drying procedure, which could rep
Comparative Analysis of Differential Cellular Transcriptome and Proteome Regulation by HIV-1 and HIV-2 Pseudovirions in the Early Phase of Infection
In spite of the similar structural and genomic organization of human immunodeficiency viruses type 1 and 2 (HIV-1 and HIV-2), striking differences exist between them in terms of replication dynamics and clinical manifestation of infection. Although the pathomechanism of HIV-1 infection is well characterized, relatively few data are available regarding HIV-2 viral replication and its interaction wi
Quantitative mass spectrometry analysis of the injured proximal and distal human digital nerve ends
Introduction: Proteomic analysis of injured human peripheral nerves, particularly focusing on events occurring in the proximal and distal nerve ends, remains relatively underexplored. This study aimed to investigate the molecular patterns underlying a digital nerve injury, focusing on differences in protein expression between the proximal and distal nerve ends. Methods: A total of 26 human injured
The COSC-2 drill core and its well-preserved lower Palaeozoic sedimentary succession – an unexpected treasure beneath the Caledonian nappes
The Collisional Orogeny in the Scandinavian Caledonides (COSC) project focuses on processes related to the closure of the Iapetus Ocean, causing the Ordovician–Silurian continent– continent collision between Baltica and Laurentia. The rock succession in the second drill core (COSC-2) from the Jämtland County, central Sweden, provides the base for detailed sedimentological, stratigraphic, geophysic
The early ontogeny of neuronal nitric oxide synthase systems in the zebrafish.
To examine a putative role for neuronal nitric oxide synthase (nNOS) in early vertebrate development we investigated nNOS mRNA expression and cGMP production during development of the zebrafish Danio rerio. The nNOS mRNA expression in the central nervous system (CNS) and periphery showed a distinct spatio-temporal pattern in developing zebrafish embryo and young larvae. nNOS mRNA expression was fi
International Biofuel Trade - A Study of the Swedish Import
Following the development of large-scale use of biomass energy in the EU, international biofuel trade is a plausible scenario and something that is already taking place in Northern Europe. This paper focuses on Swedish biofuel imports, both direct and indirect imports, the latter which derive from the fact that part of the imported pulpwood and timber end up as fuel. The objective is to describe t
Hyperfine structure, optical dephasing, and spectral-hole lifetime of single-crystalline Pr3+: La-2(WO4)(3)
Most of the experiments related to quantum information applications, involving rare-earth doped inorganic crystals, are performed on yttrium orthosilicate single crystals. The work presented here is motivated by the search of new compounds which can be used in the field of quantum computing and/or quantum storage. Relaxation times and hyperfine structure of the H-3(4)(0)-> D-1(2)(0) transition in
Drug-related problems in Parkinson's disease: the role of community pharmacists in primary care
Objective Although Parkinson's disease is a common disorder in the elderly, there have been very few studies of the role of the pharmaceutical care services in detecting and reducing problems associated with drug treatment in community settings. The aim of this study was therefore to investigate the type and frequency of drug-related problems identified in patients with Parkinson's disease by comm
Barnet och rättsprocessen : rättssäkerhet, integritetsskydd och autonomi i samband med beslut om tvångsvård
Popular Abstract in SwedishVad är barnets bästa i en domstolsprocess? Hur skall barns behov och intressen tillvaratas under utredningsarbete och beslut, och av vem? I vilken utsträckning skall barn få komma till tals, och varför? Under senare år har barns rättsliga ställning inom olika områden tilldragit allt större intresse inom rättsvetenskapen, bland rättstillämpare och hos allmänheten. SverigeThis dissertation deals with the question of the child´s legal status in legal proceedings concerning its own person. Special problems that may arise in investigations concerning the situation of the child and in decisions on measures to be taken in the best interest of the child are also examined. The Care of Young Persons Act (1990:52) constitutes the framework of this study. According to the Ac
The growth of exocrine pancreatic insufficient young pigs fed an elemental diet is dependent on enteral pancreatin supplementation
Young exocrine pancreas insufficient (EPI) pigs given a commercial feed (polymeric diet) show growth retardation that can be reversed by dietary supplementation with pancreatic enzymes. Our aim was to investigate if providing an elemental diet, mimicking a pre-digested diet, can support body growth in EPI-pigs. Thus, EPI-pigs, pancreatic duct-ligated at 12.2 +/- 2.6 weeks of age (15.3 +/- 4.8 kg),
Reproduction of Meaning and Women’s Autonomy
Metabolite evolution in the lichen family Teloschistaceae.
Invasive Breast Cancer in Malmö 1961-1992. An epidemiological study.
Popular Abstract in Swedish Malmö erbjuder speciellt goda möjligheter till epidemiologiska studier, därför att all sjukhusbunden vård erbjuds av ett enda sjukhus som dessutom i stort sett endast täcker Malmös egna behov. Därtill kommer att nu avlidne professor Folke Linell redan under 1950-talet insåg den stora betydelsen för sjukvårdens kvalitet av en omfattande obduktionsverksamhet. Under periodIn the present thesis incidence, survival, mortality, cure and prognosis in invasive breast cancer in Malmö was studied over a 30 year period. Validated data from the Cancer Registry and the Cause of Death Registry were used. In the process of validation systematical biases were identified in both registers. The incidence increased over time and was strongly related to increases in diagnostic acti
Do spermathecal morphology and inter-mating interval influence paternity in the polyandrous beetle Tribolium castaneum?
In polyandrous insects, postcopulatory sexual selection is a pervasive evolutionary force favouring male and female traits that allow control of offspring paternity. Males may influence paternity through adaptations for sperm competition, and females through adaptations facilitating cryptic female choice. Yet, the mechanisms are often complex, involving behaviour, physiology or morphology, and the
