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WILMS’ TUMOUR GENE 1 PROTEIN (WT1) – AN EFFECTOR IN LEUKEMOGENESIS?

Popular Abstract in Swedish SVENSK SAMMANFATTNING (SUMMARY IN SWEDISH) Hematopoes och leukemi Hematopoes är benämningen på den process vari alla blodceller genom hela livet kontinuerligt utvecklas i benmärgen, samt vid bildandet av lymfocyter även i lymfkörtlarna. Varje dygn bildas det ca 1012 nya celler i benmärgen för att ersätta uttjänta blodceller som dör och bryts ned. Ett litet antal stamcelWilms’ tumour gene 1 (WT1) encodes a zinc-finger transcription factor functioning as a key regulator in organ development. WT1 was first identified as a tumour suppressor gene due to its inactivation in Wilms’ tumour cases, a childhood kidney cancer. In adult tissues WT1 expression is restricted to few organs, but various forms of cancers express high WT1 levels, suggesting an oncogenic potential

Coulomb engineering of two-dimensional Mott materials

Two-dimensional materials can be strongly influenced by their surroundings. A dielectric environment screens and reduces the Coulomb interaction between electrons in the two-dimensional material. Since in Mott materials the Coulomb interaction is responsible for the insulating state, manipulating the dielectric screening provides direct control over Mottness. Our many-body calculations reveal the

The Ageing Population

The process of population ageing that has been occurring in Sweden can be expected to continue during the coming decades, the population pyramid will become increasingly rectangular, and possibly even demonstrating a shrinking base. This will lead to increasing challenges in terms of financing pensions, elderly care and healtcare. These problems will continue for at least 30 years with no demograp

Mu utbildningsplaner samlingsdokument cembalo kand

14 Utbildningsplan Musikerutbildning cembalo, 180 hp – kandidat 1. IDENTIFIKATION Programmets namn och inriktning: musikerutbildning, cembalo. Omfattning i högskolepoäng: 180. Nivå: Grundnivå (G). Programkod: KGMUS. Inriktning: CEMB. 2. BESLUTSUPPGIFTER Utbildningsplanen är reviderad och beslutad av konstnärliga fakul- tetsstyrelsen 2017-10-18. Den reviderade utbildningsplanen träder i kraft HT-17

https://www.mhm.lu.se/sites/mhm.lu.se/files/mu_utbildningsplaner_samlingsdokument_cembalo_kand.pdf - 2026-05-07

Mu utbildningsplaner samlingsdokument gitarr kand

10 Utbildningsplan Musikerutbildning gitarr, 180 hp – kandidat 1. IDENTIFIKATION Programmets namn och inriktning: musikerutbildning, gitarr. Omfattning i högskolepoäng: 180. Nivå: Grundnivå (G). Programkod: KGMUS. Inriktning: GITA. 2. BESLUTSUPPGIFTER Utbildningsplanen är reviderad och beslutad av konstnärliga fakul- tetsstyrelsen 2017-10-18. Den reviderade utbildningsplanen träder i kraft HT-17.

https://www.mhm.lu.se/sites/mhm.lu.se/files/mu_utbildningsplaner_samlingsdokument_gitarr_kand.pdf - 2026-05-07

Mu utbildningsplaner samlingsdokument piano kand

8 Utbildningsplan Musikerutbildning piano, 180 hp – kandidat 1. IDENTIFIKATION Programmets namn och inriktning: musikerutbildning, piano. Omfattning i högskolepoäng: 180. Nivå: Grundnivå (G). Programkod: KGMUS. Inriktning: PIAN. 2. BESLUTSUPPGIFTER Utbildningsplanen är reviderad och beslutad av konstnärliga fakul- tetsstyrelsen 2017-10-18. Den reviderade utbildningsplanen träder i kraft HT-17. 3.

https://www.mhm.lu.se/sites/mhm.lu.se/files/mu_utbildningsplaner_samlingsdokument_piano_kand.pdf - 2026-05-07

Om rättighetsidéen i process

Under början av förra seklet skedde en formlig reception av tysk processrätt genom Ernst Kallenbergs verk Svensk Civilprocessrätt i två band. Således kom läran om processföremålet genom 1942 års processreform att läggas till grund för utformningen av den svenska rättegångsbalken (RB). Läran om processföremålet innebär att saken är den omtvistade rättigheten i det bakom-liggande rättsförhållande soAt the turn of the last century, a formal reception of German procedural law took place through Ernst Kallenberg’s work ’Svensk Civilprocessrätt’ in two volumes. Thereby, the German doctrine on the essence of the claim formed the basis for the Swedish Code of Procedure, rättegångsbalken (RB), through the procedural reform of 1942. The doctrine on the essence of the claim holds that the matter cont

Towards proactive support for human-robot collaboration

As robots increasingly integrate into our social environments, from factories to social spaces, there is a growing need to find ways to effectively collaborate in these dynamic environments. However, current robotics research is mostly aimed towards task and environment specific programming. Even the state-of-the-art collaborative robotics technologies lack or have a very rudimentary understanding

Trends in type 1 diabetes incidence between 2007 and 2023 and their association with SARS-CoV-2 infection in a population-based matched cohort study among individuals under 30 years old in Sweden

AIMS/HYPOTHESIS: The incidence of type 1 diabetes increased during the pandemic in various countries. SARS-CoV-2 infections may trigger the development of type 1 diabetes, but the evidence is inconclusive. This study aimed to assess trends in type 1 diabetes incidence between 2007 and 2023, and to quantify the association between SARS-CoV-2 infections and the risk for developing type 1 diabetes.ME

Trust calibration in IDEs : paving the way for widespread adoption of AI refactoring

In the software industry, the drive to add new features often overshadows the need to improve existing code. Large Language Models (LLMs) offer a new approach to improving codebases at an unprecedented scale through AI-assisted refactoring. However, LLMs come with inherent risks such as braking changes and the introduction of security vulnerabilities. We advocate for encapsulating the interaction

QUPER-MAn : benchmark-guided target setting for maintainability requirements

Maintainable source code is essential for sustainable development. Yet, many studies show that maintainability often receives less attention than it deserves. We argue that requirements engineering can help close this gap by fostering discussions and setting appropriate targets in a responsible manner. In this preliminary work, we explore industry practices related to requirements engineering for

Excel isn’t a process, and not all ‘intelligence’ is smart

The relationship between requirements engineering and testing has been a key interest throughout my research career. It cannot be that requirements engineers are from Omicron Persei 7 and testers from Omicron Persei 9—we all live on the same planet. I’m happy to co-author this column with a former collaborator from a test automation EU project, now a manager at Ericsson. With this issue’s focus on

Responsible requirements engineering in a VUCA world

This column summarizes a panel discussion given by REFSQ 202 held in Barcelona on responsibility. Given the mediator role of our field, what other soft- ware engineering discipline could be a better fit for responsible engineering? And this will just keep getting more important as the influence of technology on society increases.

Sentiment analysis for the masses : how LLMs changed the game

This column presents the evolution of sentiment analysis from a requirements engineering perspective. With large language models, the technology is now accessible to all. From novices to expert users, we discuss suitable ways to get started.

From C to Rust : how feasible is it?

The C programming language, while offering high performance and low-level control, is memory-unsafe. This makes it prone to programming errors that can result in serious software vulnerabilities and system instability. In this paper, we investigate the feasibility of transitioning a large code base from C to a memory-safe alternative, specifically Rust, in the context of a large company in telecom

A critical look at the EU AI Act’s requirements and affected systems : who must explain what?

The Artificial Intelligence (AI) Act is a relatively new regulation set out in the European Union (EU). It lays out various requirements for AI systems that are placed on the market in the EU. This paper provides a critical and differentiated view of its requirements from a software engineering perspective. A detailed analysis of the legal document shows what requirements are set out for different

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This paper addresses the time-optimal path-tracking problem for redundant manipulators. By integrating path-velocity control into existing task-space robot controllers, the task-space motion can be dynamically scaled to satisfy the torque constraint under both kinematic and dynamic uncertainties. Numerical simulations and experiments demonstrate that trajectory feasibility and path-tracking accura

What do we know about software analytics research? : A critical review of secondary studies

Software analytics (SA) is often proposed as a tool to support software engineering (SE) tasks. Several secondary studies on SA have been published, some published within the same calendar year. This presents an opportunity to take a meta-perspective and examine how the field of SA has been conceptualized and synthesized so far. By analyzing how SA is defined, which topics are emphasized, what sea