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INTRODUCTION: The soluble urokinase-type plasminogen activator receptor (suPAR) has recently been associated with a decline in kidney function and incidence of chronic kidney disease in patients with cardiovascular disease undergoing cardiac catheterization, yet little is known whether suPAR is associated with deterioration of kidney function in the general population.METHODS: In the population-ba

The efficacy of cancer immunotherapy relies on the recruitment and activation of cytotoxic T cell responses against solid tumors by type 1 conventional dendritic cells (cDC1s). However, the generation of cDC1s for cancer immunotherapy faces significant limitations, including poor cell yield, functional heterogeneity, and susceptibility to immunosuppression in the tumor microenvironment (TME). We r

Treatment with warfarin in combination with clopidogrel has been shown to reduce the incidence of major bleeding as compared to triple antithrombotic therapy (TT; warfarin, clopidogrel and aspirin). However, there are uncertainties regarding the risk for thrombosis since poor-responsiveness to clopidogrel is common. Ticagrelor is a more potent platelet inhibitor, but data supporting concurrent use

The main purpose of this study was to examine the relationship between adult attachment, denoted as mental representations of childhood experiences, and social relations. A secondary purpose was to examine the impact of prematurity on attachment and social relations in adult age. The study is part of a larger longitudinal study carried out by professor Karin Stjernqvist and Anne-Li Hallin, candida

Swedish Development Cooperation emphasizes the need for collaboration among actors on a national level. In that context, the purpose of the thesis is to investigate how Public Private Partnership (PPP) on Corporate Social Responsibility (CSR) may influence the changing role of the state. The thesis is informed by Critical Discourse Analysis. In order to investigate the social constructions of real

The provision of military and armed security services typically is the monopoly domain of the state. With the end of the Cold War legitimate private firms, however, expanded as worldwide providers of military and security services. The proliferation of private military companies echoes back to pre-modern eras when it was customary for state rulers to allocate force and security through the market.

The formation of ESDP (European Security and Defense Policy) is one of the most important building blocks shaping the European security structure and the European integration process since the beginning of the 21st century. Even though the integration engine was injured by the rejection of the European Constitutional Treaty in France and the Netherlands, the ESDP can be seen as currently one of th

Elevators has for a long period of time been regarded as unsafe to use as a means of egress. This is an opinion that has shifted in the last couple of years as technical solutions has been found to the initial problems when using elevators as an escape route. This report investigates the possibility to replace a staircase with emergency elevators as a means of egress in a buildning. The report als

This paper presents the evaluation of parameters describing bond action between fiber-reinforced polymer (FRP) and concrete in RC structures strengthened in flexure. The parameters were evaluated on the basis of fitting nonlinear finite-element results to experimental results from literature. Three-dimensional (3D) finite-element simulations were used to account for transversal effects without int

Software development companies operating in market-driven domains need to deliver new and appealing software products at an increasing rate in order to stay competitive. This requires fast and efficient development of software for which the requirements are based on ever-changing market demands. Agile development claims to achieve increased development efficiency by performing the requirements eng

The galectins are known to be able to recognize and cross-link beta-D-galactopyranoside-containing glycoconjugates as a result of presenting multiple binding sites. This review summarizes efforts in our group for the last ten years towards low-molecular weight chemically modified carbohydrate derivatives. In addition to providing an avenue for improved affinity and galectin-selectivity, we have fo

A high intake of omega-3 polyunsaturated fatty acids (ω-3 PUFAs), has been associated with reduced levels of blood pressure (BP). Their antihypertensive action may be due to the reduction of the ω-6/ω-3 ratio and the resulting competitive effect of ω-3 as compared to arachidonic acid (an ω-6 PUFA) as a substrate of cytochrome P450 (CYP450) enzymes involved in the production of vasoactive mediators

Enzymatic pretreatment of algae by means of cellulose degrading enzyme was evaluated through lab-scale and pilot-scale experiments. The degradation efficiency of the enzyme depended on the initial physical quality of the algae. Lab-scale batch anaerobic digestion experiments showed comparatively low methane potential for the pretreated algae at both mesophilic and thermophilic temperatures. Howeve

Background: Immigrants from the Middle-East are at high risk of developing type 2 diabetes (T2D). The aim of the present survey was to measure, in a single deprived neighbourhood, the prevalence rates of impaired fasting glucose (IFG), impaired glucose tolerance (IGT) and T2D in residents originating from Iraq and to compare them to those in residents born in Sweden. An additional aim was to ident

Desertification, climate variability and food security are closely linked through drought, land cover changes, and climate and biological feedbacks. In Ghana, only few studies have documented these linkages. To establish this link the study provides historical and predicted climatic changes for two drought sensitive agro-ecological zones in Ghana and further determines how these changes have influ

En lantmäteriförrättning vars syfte till största del är att undvika stämpelskatt kallas “skatteförrättning”. Genom reglerna i FBL kan köpare av fast egendom i vissa situationer undkomma reglerna kring lagfart i JB och därmed undvika stämpelskatt för förvärvet. I aktuella situationer är köparen ägare av en fastighet till vilken det tänkta köpeobjektet regleras. Skattelättnaden är i sig inget hindA cadastral procedure with the intent to avoid paying stamp duty for particular real estate transactions is a well-known phenomenon in Sweden. By using the rules in the Property Formation Act stamp duty can be avoided. In order to comply with the rules in the Property Formation Act the buyer has to already own real estate, to which the recently acquired land parcel can be transferred. The Cadastra

BAKGRUND På grund av att företag idag har möjlighet att konkurrera globalt genom att flytta produktionen utomlands och att säkra leveranser ifrån alla världens hörn har också inköpsfunktionens roll förändrats. För att nå företagets uppsatta mål är det viktigt att ha en välfungerande inköpsfunktion som jobbar effektivt. Inköpsfunktionen bör inte enbart fokusera på att uppnå det billigaste möjliga iBACKGROUND Through global competition with possibilities for companies to set up production and to secure supply from all over the world the role of purchasing has increased within businesses. In order to achieve business results, a well-working purchasing department plays an important part. To contribute, the purchasing function should not only focus on getting the cheapest price possible, but to

Enterprise Resource Planning (ERP) systems have been used by organizations and companies throughout the world since 1990. Many universities have recently replaced their legacy systems with ERP systems to improve work efficiency. One solution available for universities by way of management information system is the Campus ERP system. The Campus ERP system helps universities incorporate all departme