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From Birth to Midlife-Liver Function, Fibrosis and Mortality in Individuals with Severe Alpha-1-Antitrypsin Deficiency Identified by Neonatal Screening

Background: Severe Alpha-1-Antitrypsin deficiency (AATD), phenotype PiZZ, is a leading cause of liver disease in neonates, children, and adults. Nevertheless, the prevalence of liver disease and mortality within PiZZ adults remains unclear. Between 1972 and 1974, a cohort of 129 individuals with severe AATD (PiZZ) was identified through the Swedish national screening of 200,000 newborns. The cohor

Metabolic syndrome and venous thromboembolism : the role of abdominal obesity and sex differences

Metabolic syndrome (MetS) is a cluster of cardiovascular risk factors, including abdominal obesity, insulin resistance, dyslipidemia, and hypertension. Its association with venous thromboembolism (VTE) has been inconsistently reported. We investigated the association between MetS and VTE, and the influence of sex and abdominal obesity. We included 12,788 middle-aged and older adults from the re-ex

Parametric Study on the Growth of Type-II InSb Quantum Dots on InAs Substrates by Molecular Beam Epitaxy

The formation of InSb quantum dots (QDs) embedded in an InAs matrix grown by molecular beam epitaxy (MBE) was studied parametrically. In particular, the effect of the sequence of the change of As2 dimers and Sb2 on the distribution of As and Sb at the InSb-QDs/InAs interface was investigated by cross-sectional transmission electron microscopy (TEM). It was shown that additional As2 above the InSb

Multi-objective optimization framework for reconfigurable PV–PEM electrolyzer using machine learning surrogates

Optimization and electrical control of photovoltaic (PV) and proton exchange membrane (PEM) electrolyzer systems are critical for efficient, scalable hydrogen production. Static coupling methods employ fixed electrical interconnections between PV arrays and the PEM stack, which cannot adapt to fluctuating irradiance or temperature. To overcome this, we propose an adaptive reconfiguration optimizat

Pacheco alberto 2

LUMES Lund University International Master’s Programme in Environmental Science SUSTAINABLE FINANCE: An assessment of environmental risks and opportunities in Latin America Alberto Pacheco Capella Tel. +46-70-466-1593 Email: alberto.pacheco@unep.ch Supervisor: Tareq Emtairah, PhD Candidate International Institute for Industrial Environmental Economics (IIIEE) Email: tareq.emtairah@iiiee.lu.se Thes

https://www.lumes.lu.se/sites/lumes.lu.se/files/pacheco_alberto_2.pdf - 2026-05-10

The Viral AlphaFold Database of monomers and homodimers reveals conserved protein folds in viruses of bacteria, archaea, and eukaryotes

Viruses are the most abundant and genetically diverse entities on Earth, yet the functions and evolution of most viral proteins remain poorly understood. Their rapid evolution often obscures evolutionary relationships, limiting the ability to assign functions using sequence-based methods. Although the conservation of protein fold can reveal deep homologies, viral proteins remain underrepresented i

Transplanted human striatal progenitors exhibit functional integration and modulate host circuitry in a Huntington's disease animal model

Huntington's disease (HD) is a fatal neurodegenerative disorder caused by a CAG repeat expansion in the HTT gene. This leads to progressive loss of striatal neurons and motor-cognitive decline. While current gene-targeting approaches aiming at reducing somatic instability show promise – especially in case of early treatment – they cannot restore the already compromised neuronal circuitry at advanc

Fabrication and characterization of high-tensile-strength PEO-PVP blend-based multifunctional composites for sodium-ion structural batteries

The structural integration of energy storage could play a pivotal role in designing more efficient, lightweight systems such as electric transport, internet of things (IoT) devices and autonomous systems. The current work focuses on the fabrication and characterization of novel multifunctional composites for sodium-ion structural batteries. A PEO-PVP polymer matrix with added InAs nanowires and gl

Internutbildningar inom ekonomi/inköp

Sektionen Ekonomi och några andra enheter inom centrala förvaltningen håller i ett paket med utbildningar både för dig som är ny som ekonom/inköpare och för dig som arbetat ett tag och önskar fördjupa dig i ett ämne. Rätt kurs i rätt tid På denna sida får du en överblick över de kurser som riktar sig till dig som arbetar som ekonom/inköpare vid universitetet. Samtliga kurser finns på Kompetensport

https://www.ekonomiwebben.lu.se/mitt-arbete/overgripande-om-ekonomi-och-redovisning/internutbildningar-inom-ekonomiinkop - 2026-05-09

Thermal Considerations in Bulk Acoustic Wave Devices towards Optimised Acoustofluidics

The main goal of my studies was obtaining bulk acoustofluidic devices able to achieve high energy density inside a water-filled cavity. This led us to explore the interplay of sound and thermal effects more in details. Hence, this thesis covers both thermoacoustic effects in Bulk Acoustic Wave devices and a revisited approach for designing them, focusing on achieving good performance. Thermoacoust

Templated electrodeposition as a scalable and surfactant-free approach to the synthesis of Au nanoparticles with tunable aspect ratios

A high-throughput method for the fabrication of ordered arrays of Au nanoparticles is presented. It is based on pulsed electrodeposition into porous anodic alumina templates. In contrast to many synthesis routes, it is cyanide-free, prior separation of the alumina template from the aluminium substrate is not required, and the use of contaminating surfactants/capping agents often found in colloidal

Comparison of Outcomes After Revascularization for Acute Lower Limb Ischemia in Patients with and without Type 2 Diabetes Mellitus – A Nationwide Registry Study

Introduction: Acute lower limb ischemia (ALI) is a life and limb threatening event often affecting patients with type 2 diabetes mellitus (T2DM). Little is known about how T2DM affects the risk of adverse events in patients revascularized for ALI. This study aimed to investigate if there were differences in major outcomes between ALI patients with and without T2DM. Methods: Between 2010 and 2014,

Genotype-stratified treatment for monogenic insulin resistance: a systematic review

BackgroundMonogenic insulin resistance (IR) includes lipodystrophy and disorders of insulin signalling. We sought to assess the effects of interventions in monogenic IR, stratified by genetic aetiology.MethodsSystematic review using PubMed, MEDLINE and Embase (1 January 1987 to 23 June 2021). Studies reporting individual-level effects of pharmacologic and/or surgical interventions in monogenic IR

Protocol for 3D direct reprogramming of human glia into dopaminergic neurons with gene expression and immunocytochemistry validation

Direct reprogramming of somatic cells into neurons offers a promising strategy for studying neurological disorders and developing cell-based therapies. This protocol describes the 3D direct reprogramming of human glial progenitor cells into dopaminergic neurons. It includes spheroid formation, lentiviral transduction, neuronal induction using doxycycline, and validation via gene expression and imm

Does exposure to black carbon during pregnancy increase the risk of autism spectrum disorder? A cohort study from Southern Sweden

Black carbon (BC), a major component of fine particulate matter (PM2.5), has been implicated in adverse neurodevelopmental outcomes, including autism spectrum disorders (ASD). While PM2.5 has been associated with increased ASD risk, the specific role of BC remains uncertain. This study aimed to assess prenatal exposure to BC and risk for ASD development in a low exposure setting, using a large, hi

GDNF and Parkinson's Disease : Where Next? A Summary from a Recent Workshop

The concept of repairing the brain with growth factors has been pursued for many years in a variety of neurodegenerative diseases including primarily Parkinson's disease (PD) using glial cell line-derived neurotrophic factor (GDNF). This neurotrophic factor was discovered in 1993 and shown to have selective effects on promoting survival and regeneration of certain populations of neurons including

Neuronal Replacement as a Tool for Basal Ganglia Circuitry Repair : 40 Years in Perspective

The ability of new neurons to promote repair of brain circuitry depends on their capacity to re-establish afferent and efferent connections with the host. In this review article, we give an overview of past and current efforts to restore damaged connectivity in the adult mammalian brain using implants of fetal neuroblasts or stem cell-derived neuronal precursors, with a focus on strategies aimed t

H16 litteraturlista gnva20

Brevmall Postadress Box 117 221 00 Lund Besöksadress Allhelgona kyrkogata 14 M Telefon 046-222 08 01 Webbadress www.genus.lu.se Genusvetenskapl iga ins t i tu t ionen GNVA20 Genusvetenskap: Grundkurs Delkurs 1: Introduktion till genusvetenskap I, 7,5 hp Becker, Howard S. (1998). Tricks of the Trade: How to Think about Your Research While You’re Doing It. Chicago: Chicago University Press. (utvalt

https://www.genus.lu.se/sites/genus.lu.se/files/h16_litteraturlista_gnva20.pdf - 2026-05-10

Luvre-1211999enemarmflaggstorlek

Namnl.st-36 1 ORNIS SVECICA 9:1–10, 1999 Egg sizes of nine passerine bird species in a subalpine birch forest, Swedish Lapland Abstract ANDERS ENEMAR & OLA ARHEIMER Egg measurements together with calculated volumes are presented for nine passerine species (Prunella modularis, Luscinia svecica, Phoenicurus phoenicurus, Turdus pila- ris, Turdus philomelos, Turdus iliacus, Phylloscopus tro- chilus, F

https://www.luvre.lu.se/sites/luvre.lu.se/files/luvre-1211999enemarmflaggstorlek.pdf - 2026-05-10

Nyhetsbrev2016 tg

GÅS Nyhetsbrev för året 2016 Nyhetsbrev 2016 till dig som deltar i ett världsunikt projekt Stort deltagande när GÅS i Malmö hade Öppet Hus Anna Cewe Jönsson, deltagare, till höger, får tips av Zinka Tucek, GÅS-medarbetare, till vänster. Ett par hundra personer hade hörsammat funnit att kvinnor kan ha en högre risk än män att vår inbjudan och kommit till Öppet Hus utveckla KOL, att risken att få sj

https://www.geriatrik.lu.se/sites/geriatrik.lu.se/files/nyhetsbrev2016_tg.pdf - 2026-05-10