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Selenoprotein P predicting mortallity in acute ill patients with dyspnea

Background and aims: Good Selenium (Se) status predicts favorable prognoses for various diseases and a reduced overall mortality. The primary objective of the study was to determine whether Selenium status, i.e. Selenoprotein P (SeP) levels, is associated with risk of 90-day mortality in elderly patients with acute dyspnea at the Emergency Department (ED). Methods and results: Patients presenting

Unconventional gap structures and the intermediate mixed state: A vortex lattice study of the noncentrosymmetric superconductor BiPd

We report on neutron scattering measurements on the vortex lattice of the noncentrosymmetric superconductor BiPd. We observe the existence of the intermediate mixed state, a region where Meissner and vortex lattice phases coexist, which is a feature of low type-II superconductors. Following this, we obtain an estimate of the value of using the extended London model. Finally, we find that the tempe

Toxicity of carbon nanomaterials : A model to predict ROS production from easily measurable surface characteristics

Toxicity pathways of engineered carbon nanomaterials, which have many and diverse industrial applications, include oxidative stress primarily due to the generation of reactive oxygen species (ROS). This study on 13 carbon black, 6 Graphene nanoplatelets (GNP), and 3 nanodiamond materials identified physicochemical properties driving their ROS production. ROS production was cross-validated using di

Blood levels of Mycobacterium tuberculosis (Mtb)antigen-triggered immune markers in people exposed to tuberculosis with regard to Mtb infection status and receipt of tuberculosis preventive therapy

Background: Interferon-γ release assays (IGRAs) for tuberculosis infection (TBI) cannot distinguish different stages of the TBI spectrum (including spontaneously cleared infection). We investigated patterns of Mtb-specific blood mediators in people with and without TBI during tuberculosis preventive therapy (TPT). Methods: Individuals with likelihood of recent Mtb exposure, aged 15–25 years, with

Oxidation of carbon nanomaterials using a nanoparticulate iron oxide catalyst : Direct observations in an electron microscope

Understanding of carbon nanomaterials oxidation is useful in many different applications, e.g., for soot emission abatement, or in defect engineering aiming to improve material properties. In this work, the oxidative behavior of three substantially different qualities of carbon black, multiwall carbon-nanotubes, and few-layer graphene, was studied using a combination of macroscale quantification (

Brain perfusion and blood-brain barrier permeability in systemic lupus erythematosus patients : Associations with disease activity, cognitive dysfunction, fatigue and pain

High disease activity, cognitive dysfunction (CD), fatigue and pain negatively affect the quality of life in patients with systemic lupus erythematosus (SLE). However, the impact on brain perfusion and blood-brain barrier (BBB) permeability remains incompletely understood. Therefore, we utilized 3 T dynamic susceptibility contrast magnetic resonance imaging to investigate these factors in a cohort

Influence of the laser pulse duration in high-order harmonic generation

High-order harmonic generation (HHG) in gases is inherently inefficient, prompting ongoing efforts to enhance the output of coherent table-top XUV sources. In this study, we investigate the influence of the laser pulse duration on HHG using a compact post-compression method featuring a bulk multi-pass cell. This setup enables tunable Fourier-limited pulse durations as short as 42 fs. We examine th

Magnetic Lyddane-Sachs-Teller Relation

We describe a magnetic relation in analogy to the well-known dielectric Lyddane-Sachs-Teller relation [R. H. Lyddane et al., Phys. Rev. 59, 673 (1941)PHRVAO0031-899X10.1103/PhysRev.59.673]. This magnetic relation follows directly from the model equations for nuclear induction due to fast oscillating electromagnetic fields [F. Bloch, Phys. Rev. 70, 460 (1946)PHRVAO0031-899X10.1103/PhysRev.70.460] a

Two Characteristic Contributions to the Superconducting State of 2H−NbSe2

Multiband superconductivity arises when multiple electronic bands contribute to the formation of the superconducting state, allowing distinct pairing interactions and gap structures. Here, we present field- and temperature-dependent data on the vortex lattice structure in 2H-NbSe2 as a contribution to the ongoing debate as to whether the defining feature of the superconductivity is the anisotropy

Composition tunable and stable spontaneous emission and lasing in Cd-alloyed perovskite microdisks

All-inorganic Pb-Cd mixed-cation halide perovskites have emerged as semiconductors exhibiting improved optical and optoelectronic properties. We establish a reliable correlation between photoluminescence and Cd content x in bulk CsPb1−xCdxBr3 compositions, propose pathways of photoexcited charge carrier dynamics in them, and show improved stability of lasing in whispering gallery mode microdisks.

Development of crystal optics for X-ray multi-projection imaging for synchrotron and XFEL sources

X-ray multi-projection imaging (XMPI) is an emerging experimental technique for the acquisition of rotation-free, time-resolved, volumetric information on stochastic processes. The technique is developed for high-brilliance light-source facilities, aiming to address known limitations of state-of-the-art imaging methods in the acquisition of 4D sample information, linked to their need for sample ro

Decoherence in a crystal-phase defined double quantum dot charge qubit strongly coupled to a high-impedance resonator

Decoherence of a charge qubit is usually credited to charge noise in the environment. Here we show that charge noise may not be the limiting factor for the qubit coherence. To this end, we study coherence properties of a crystal-phase defined semiconductor nanowire double quantum dot (DQD) charge qubit strongly coupled to a high-impedance resonator using radio-frequency reflectometry. Response of

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

Few genome-wide association studies (GWAS) account for environmental exposures, like smoking, potentially impacting the overall trait variance when investigating the genetic contribution to obesity-related traits. Here, we use GWAS data from 51,080 current smokers and 190,178 nonsmokers (87% European descent) to identify loci influencing BMI and central adiposity, measured as waist circumference a

Influence of final state interactions in attosecond photoelectron interferometry

Fano resonances are ubiquitous phenomena appearing in many fields of physics, e.g., atomic or molecular photoionization, or electron transport in quantum dots. Recently, attosecond interferometric techniques have been used to measure the amplitude and phase of photoelectron wave packets close to Fano resonances in argon and helium, allowing for the retrieval of the temporal dynamics of the photoio

Transancestral mapping and genetic load in systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is an autoimmune disease with marked gender and ethnic disparities. We report a large transancestral association study of SLE using Immunochip genotype data from 27,574 individuals of European (EA), African (AA) and Hispanic Amerindian (HA) ancestry. We identify 58 distinct non-HLA regions in EA, 9 in AA and 16 in HA (50% of these regions have multiple independe

Spectral Tuning, Stabilities under External Exposures, and Spontaneous Enhancement of Emission Intensity in Grown-into-Glass All-Inorganic Metal Halide Perovskite Nanocrystals

Herein, the grown-into-glass (GIG) CsPbBr3:Ln3+ (Ln = La, Lu) nanocrystals (NCs) are designed and fabricated using an in situ nanocrystallization method. It is shown that a substitution of Pb2+ sites with Ln3+ ions leads to a blueshift of emission position induced by an increase of the bandgap of CsPbBr3. Additionally, the GIG-samples are found to feature excellent photoluminescent (PL) properties

Impact of Al profile in high-Al content AlGaN/GaN HEMTs on the 2DEG properties

Ultra-thin high-Al content barrier layers can enable improved gate control and high-frequency operation of AlGaN/GaN high electron mobility transistors (HEMTs) but the precise composition control is very challenging. In this work, we investigate the compositional profiles of AlxGa1−xN/GaN HEMT structures with targeted Al content in the barrier layer, x = 0.50, 0.70, and 1, and thickness in the sub

Deficiency of Peptidylglycine-alpha-amidating Monooxygenase, a Cause of Sarcopenic Diabetes Mellitus

Context: Peptidylglycine-α-amidating monooxygenase (PAM) is a critical enzyme in the endocrine system responsible for activation, by amidation, of bioactive peptides. Objective: To define the clinical phenotype of carriers of genetic mutations associated with impaired PAM-amidating activity (PAM-AMA). Design: We used genetic and phenotypic data from cohort studies: the Malmö Diet and Cancer (MDC;

Direct observations of nucleation and early-stage growth of Au-catalyzed GaAs nanowires on Si(111)

Developing a reliable procedure for the growth of III-V nanowires (NW) on silicon (Si) substrates remains a significant challenge, as current methods rely on trial-and-error approaches with varying interpretations of critical process steps such as sample preparation, Au-Si alloy formation in the growth reactor, and NW alignment. Addressing these challenges is essential for enabling high-performanc