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Background: Islet autoantibodies form the foundation for type 1 diabetes (T1D) diagnosis and staging, but heterogeneity exists in T1D development and presentation. We hypothesized that autoantibodies can identify heterogeneity before, at, and after T1D diagnosis, and in response to disease-modifying therapies. Methods: We systematically reviewed PubMed and EMBASE databases (6/14/2022) assessing 10
This article explores the regional embeddedness of bioeconomy innovations in Germany, focusing on “flagship” innovation projects that exemplify the challenges and opportunities of systemic changes towards bioeconomies. While bioeconomies have been promoted as solutions to global challenges and opportunities for sustainable regional development, there are ongoing debates about the actual benefits o
Background: The objective of this systematic review is to identify prognostic factors among women and their offspring affected by gestational diabetes mellitus (GDM), focusing on endpoints of cardiovascular disease (CVD) and type 2 diabetes (T2D) for women, and cardiometabolic profile for offspring. Methods: This review included studies published in English language from January 1st, 1990, through
Aerosol surface composition plays a critical role in atmospheric chemistry but remains poorly characterized, especially for inorganic systems lacking organic surfactants. While bulk composition is typically measured, key interfacial processes, including heterogeneous reactions, water uptake, and cloud activation, occur at the surface. Here, we present the first depth-resolved, in-flight X-ray phot
The traditional approaches rely solely on temperature measures to assess heat-related health risks; but there is a growing trend towards using bio-meteorological indices for a more comprehensive evaluation. However, the adoption of bio-meteorological indices in developing countries is considerably limited. Therefore, this study compares bio-meteorological index, the maximum Universal Thermal Clima
Aqueous lithium-ion batteries (ALIBs) are promising for large-scale energy storage systems because of the cost-effective, intrinsically safe, and environmentally friendly properties of aqueous electrolytes. Practical application is however impeded by interfacial side-reactions and the narrow electrochemical stability window (ESW) of aqueous electrolytes. Even though higher electrolyte salt concent
Recent progress in “water-in-salt” electrolytes (WiSEs) and “hybrid aqueous/non-aqueous electrolytes (HANEs)” made broader choices of active material in aqueous Li-ion batteries (ALIBs), because of their compared to standard aqueous electrolytes expanded electrochemical stability windows (ESWs). Exploring high energy density ALIBs is a consequently meaningful research topic. However, the formation
Among the many approaches to improve the performance of lithium-metal batteries, ternary polyethylene oxide/ionic liquid/lithium salt electrolytes offer several advantages such as low flammability, high conductivity (vs. polyethylene oxide/lithium salt electrolytes) and, to a large extent, limiting the growth of dendrites at moderate currents. However, they suffer from relatively low mechani
Background: Chronic kidney disease (CKD) affects 6–10% of adults and often remains undiagnosed until advanced stages, leading to inadequate management. This study compared diagnosed, proxy-diagnosed, and undiagnosed CKD patients regarding prevalence, clinical assessment, nephroprotective treatment, healthcare utilization, and mortality. Methods: This retrospective observational study analyzed Regi
The aggregation of tau into amyloid fibrils is associated with Alzheimer’s disease (AD) and related tauopathies. Since different tauopathies are characterized by the formation of distinct tau fibril morphologies, it is important to combine the search of tau aggregation inhibitors with the development of in vitro tau aggregation assays that recapitulate aggregation as it may occur in the brain. Her
We study two-dimensional, stationary square and hexagonal patterns in the thermocapillary deformational thin-film model for the fluid height h [Formula presented] that can be formally derived from the Bénard–Marangoni problem via a long-wave approximation. Using a linear stability analysis, we show that the flat surface profile corresponding to the pure conduction state destabilises at a critical
How is Turkish official memory negotiated locally in Izmir, a city celebrated as a symbol of national becoming, yet (im)famous for its scepticism of central power? How is the past of the city narrated, conceived as an epitome of progress, yet built on a systematic forgetting of trauma and violence? And how does the secularist legacy of Izmir, accentuated in contrast with the Islamisation of memory
Context. Strongly lensed quasars are fundamental sources for cosmology. The Gaia space mission covers the entire sky with the unprecedented resolution of 0.18âà € ³ in the optical, making it an ideal instrument to search for gravitational lenses down to the limiting magnitude of 21. Nevertheless, the previous Gaia Data Releases are known to be incomplete for small angular separations such as thos
Brain organoid technology has seen significant development in recent years. This self-organized, three-dimensional, organ-oriented brain tissue model can recapitulate the process of neurogenesis and consists of diverse cell types and cellular architecture. Transplanting brain organoids in vivo could be a potential tool from bench to clinical research and has been studied for many purposes. To inve
Improving accuracy and timeliness for osteoporosis diagnosis could help prevent fragility fractures, morbidity, and mortality for older individuals. Osteoporosis is an often silent health condition, especially as regards vertebral fractures, and WHO issued a call to action for primary care to lead efforts in screening, assessing, and managing diseases such as osteoporosis. We used a machine learni
Ibrutinib was approved for relapsed/refractory (R/R) mantle cell lymphoma (MCL) based on high response rates in clinical trials, but it is unclear how effective ibrutinib is in the real-world setting. This study provides population-based response rates and survival estimates and characterization of prognostic indicators and adverse events (AEs) to ibrutinib for patients with R/R MCL. All patients
KCS_Verksamhetsplan 2018 Verksamhetsplan - Körcentrum Syd 2018 Inledning Nedanstående verksamhetsplan för år 2018 i Körcentrum Syd har fastställts av Körcentrum Syds styrelse, 2018-02-26. Körcentrum Syd är en centrumbildning inrättad av Lunds Universitet. I Körcentrum Syds styrelse är följande institutioner representerade: Lunds Universitet med Musikhögskolan i Malmö och Odeum, Lars Erik Larsson-g
https://www.korcentrumsyd.lu.se/sites/korcentrumsyd.lu.se/files/kcs_verksamhetsplan_2018_0.pdf - 2026-07-05
Bibl io tekss tyrel sen Närvarande Ledamöter Olov Sterner dekanus, naturvetenskapliga fakulteten, ordförande Gudrun Edgren professor, medicinska fakulteten Per Nilsén prefekt, juridiska fakulteten Jan-Åke Nilsson professor, naturvetenskapliga fakulteten Jens Nockert studeranderepresentant Anders Törnkvist studeranderepresentant (t o m punkt 12) Kristian Jensen Head of Collections and Curation, Bri
https://www.lub.lu.se/sites/lub.lu.se/files/protokoll_bs_20160215.pdf - 2026-07-05
Title: A qualitative and quantitative analysis of the risk parameter LGD based on the Basel II Framework Seminar date: 27 January 2007 Course: Financial Economy, Master Thesis, 10 poäng (15 ECTS) Author: Helén Dybing Advisor: Hans Byström Key words: LGD, LTV, Risk, Basel II, Estimation model Purpose: The purpose of this thesis is to get a deeper understanding of the risk parameter LGD and try to i
