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Telomeres are protective cap structures at the ends of the linear eukaryotic chromosomes, which provide stability to the genome by shielding from degradation and chromosome fusions. The cap consists of telomere-specific proteins binding to the respective single- and double-stranded parts of the telomeric sequence. In addition to the nucleation of the chromatin structure the telomere-binding protei
Objectives: To investigate and establish the prevalence of dementia with Lewy body (DLB) symptoms in all nursing home (NH) residents in Malmö, the third largest city in Sweden. DLB is a neurocognitive disorder with core features, such as parkinsonism, visual hallucinations, and fluctuating cognition/excessive daytime sleepiness, and supportive features, such as rapid eye movement sleep behavior di
This paper analyses the use of wonder in the TV-series Cosmos: A Personal Voyage (1980). Popular science has been studied extensively (e.g. Broks 2006; Leane 2007; Perrault 2013), and wonder has been studied moderately (e.g. Daston & Park 1998; Fuller 2006; Vasalou 2015). However, there are very few studies of wonder in popular science. This paper explores how and why wonder is used in Cosmos,
Surface adsorption of Thermomyces lanuginosus lipase (TLL) - a widely used industrial biocatalyst - is studied experimentally and theoretically at different pH and salt concentrations. The maximum achievable surface coverage on a hydrophobic surface occurs around the protein isoelectric point and adsorption is reduced when either increasing or decreasing pH, indicating that electrostatic protein-p
Importance: The ability to predict sudden cardiac death (SCD) in children and adolescents with hypertrophic cardiomyopathy (HCM) is currently inadequate. Late gadolinium enhancement (LGE) by cardiovascular magnetic resonance (CMR) imaging is associated with SCD events in adults with HCM. Objective: To examine the prognostic significance of LGE in patients with HCM who are younger than 21 years. De
Do the characteristics that motivated non-Jews to rescue Jews during the Holocaust also predict morally courageous intentions in today’s high school students? Swedish students (N = 231) completed a survey assessing parental role modelling, empathic concern, risk-taking, and identification with outgroups, indicating whether they would intervene to help persecuted Jews and Muslims in various scenari
Helsingborg has a strong trading heritage and a unique strategic location within the Nordic region. It's no coincidence that these factors have combined in the digital age to position Helsingborg as a key player in the world of e-commerce.The city's natural geographic advantages, alongside significant investments in infrastructure, have established a strong foundation for Helsingborg to become a l
Mexico, the second largest economy in Latin America, has almost eradicated extreme poverty according to the Millennium Development Goals; however, official statistics show that by national standards poverty levels are still quite high, reaching up to half its population. This paper looks into how the determinants of poverty in Mexico have evolved after the last major economic crisis the country ex
This thesis concerns oaths, curses, and prayers in Roman comedy, more precisely the comedies by the playwriter Terence (185/84 - 159 BC). So-called informal/interjectional oaths and prayers constitute the main focus of this investigation, however, asseverations, formal oaths, formal prayers, and curses are included as well. In this study, carried out by utilizing the methodological frameworks herm
In this master's thesis a fully automated method is presented for seg-menting bones and cartilage in magnetic resonance imaging (MRI) of theknee. The knee joint is the most complex joint in the human body andsupports the weight of the whole body. This complexity and acute task ofthe knee joint leads to a disabling disease called Osteoarthritis among theadult population. The disease leads to loss o
We present time-resolved three-dimensional measurements of the averaged liquid mass distribution generated by the Spray M from the Engine Combustion Network. The operating condition corresponds to a non-reacting early injection case for spray-guided gasoline injection during the first 200 μs. Few-femtosecond X-rays from a compact laser wakefield accelerator, enable quantitative spray measurements,
Hazardous situations involving radioactive, chemical, and other dangerous materials pose significant risks to emergency responders. In such situations, robots can support civil forces in reconnaissance and mitigation. However, this requires the development of robotic systems with novel AI-based assistance functions, operation procedures, and raises new ethical and legal questions. To address these
Objectives: The aim of the present study was to assess if vortex formation time (VFT) as a measurement of left ventricular (LV) diastolic function is affected by food intake and related to age and sex. Methods: Healthy participants were divided into two age groups: younger (median age: 25 years) and older (median age: 68 years). Transthoracic echocardiography (TTE) examinations were performed duri
Pregnancy and lactation require large amounts of calcium potentially depleting the young adult bone. This study investigated BMD and fluctuations of BMD resulting from parity and lactation in the PEAK-25 cohort, a prospective observational study of women all aged 25 at inclusion and 35 at follow-up. The analyses use women who were nulliparous at baseline and parous (n = 573) or nulliparous (n = 17
Drawing on actor-network theory and theories of performance, this article discusses gift-giving as an expansive form of materializing relationships and delimiting boundaries between nations, regions, organizations and individuals in the wake of migration. Initially, I discuss gift-giving as a way of materializing relationships and building networks. Thereafter, I map out the social life of the Vär
Background: Opioid use disorder is a chronic disorder with a high risk of overdose-related morbidity and mortality where a large proportion of these can be averted by timely administration of the antidote naloxone. For naloxone to be present when and where overdoses occur, broad-scale overdose education and naloxone distribution (OEND) must be established. A regional naloxone program was implement
Objective: A diagnosis of childhood cancer is profoundly devastating for families, with well-recognized effects on parental mental health. However, its impact on parental somatic health remains poorly understood, particularly regarding potential long-term cumulative burden. These persistent somatic diseases require frequent clinic visits for ongoing management and adversely affect parents' quality
Corpus linguistic studies have shown that lexicon varies according to linguistic register, and cognitive studies have demonstrated that lexical aspects play a significant role in determining the veracity of people’s accounts. Both lines of research underpin the present study, where the aim is to explore how overall lexical properties (lexical density and lexical diversity, and noun, verb, and adje
Data-driven modeling frameworks have become essential tools for guiding surveillance strategies and informing public health policies across diverse population health challenges. Accurate, fine-scale disease estimates often lacking from direct surveys are critical for policy planning, given that spatial heterogeneity and nonlinear dynamics among determinants of health challenge classical models, li
