Filetype
OBJECTIVES To examine which individual and environmental factors correlate with unmet physical activity need in old age and predict development of unmet physical activity need (the feeling that one's level of physical activity is inadequate and thus distinct from the recommended amount of physical activity) over a 2-year follow-up. DESIGN Observational prospective cohort study and cross-sectional
The two major forms of the amyloid-beta (Aβ) peptide found in plaques in patients suffering from Alzheimer's disease, Aβ40 and Aβ42, only differ by two amino acids in the C-terminal region, yet they display markedly different aggregation behavior. The origins of these differences have remained challenging to connect to specific molecular-level processes underlying the aggregation reaction. In this
The purpose of this study was to test napsin A as a diagnostic marker of metastatic lung adenocarcinoma in pleural effusions, and to compare its performance with TTF-1. Napsin A and TTF-1 reactivities were determined immunohistochemically on.formalin-fixed paraffin embedded cell blocks from 50 pleural effusion (5 mesotheliomas, 10 mesothelial proliferations, 12 pulmonary, and 23 nonpulmonary metas
Although there is a high degree of homology in the M2 transmembrane segments of alpha1 and beta1 subunits, subunit-specific effects were observed in alpha1beta1 GABA(A) receptors expressed in Spodoptera frugipedra (Sf9) cells when the conserved 13' threonine residue in the M2 transmembrane region was mutated to alanine. When threonine 263 (13') was mutated to alanine in the beta1 subunit, high-aff
The purpose of this study was to gain an enhanced understanding of how people with multiple sclerosis (MS) experience their engagement in occupations. We interviewed 10 people and then analyzed the data gathered using the constant comparative method of grounded theory, The findings encompassed the core category "essentials of a constantly changing life," showing that along a continuum of change, t
In this study we present the results from realistic N-body modelling of massive star clusters in the Magellanic Clouds. We have computed eight simulations with N similar to 10(5) particles; six of these were evolved for at least a Hubble time. The aim of this modelling is to examine in detail the possibility of large-scale core expansion in massive star clusters, and search for a viable dynamical
The neutron-deficient nucleus La-123 was studied via the Mo-92(Ca-40,2ap) reaction at a beam energy of 184 MeV. Previously known bands were extended to a much higher spin, and in two cases the structures are now observed near 40 (h) over bar. In addition, three new sequences were identified and linked into previously known bands. The lowest (pi,alpha)=(+,-1/2) structure displays characteristics si
There is growing awareness that the profound changes in the environment (eg, in diet and other lifestyle conditions) that began with the introduction of agriculture and animal husbandry approximate to10 000 y ago occurred too recently on an evolutionary time scale for the human genome to adjust. In conjunction with this discordance between our ancient, genetically determined biology and the nutrit
High-spin states of a number of nuclei near Ni-56 have been studied by means of the Si-28(Ar-36,x alpha ypzn) reaction. The GAMMASPHERE array in conjunction with light charged particle and neutron detectors were used to identify and cleanly select the fusion-evaporation products. In addition to significantly extending the level schemes of many previously known N = Z nuclei from Fe-52 to Cu-58, exc
The majority of microarray studies focus on analysis of gene expression differences between various specimens or conditions. However, the causes of this variability from one cancer to another, from one sample to another and from one gene to another often remain unknown. In this study, we present a systematic procedure for finding genes whose expression levels are altered due to an intrinsic or ext
The aim of this study was to study the relationship between physician-assessed quality of life parameters, i.e., toxicity and physical performance, and patients' self-reports of their quality of life (QoL). QoL was assessed at baseline and before each treatment. using the EORTC QLQ-C30. The WHO performance score (PS) and toxicity were assessed in physician interviews. The correlations between the
The phase and electrochemical behavior of the aqueous mixtures of monoolein (MO) and synthetic ferrocene (Fc) derivatives containing long alkyl chains -(Z)-octadec-9-enoylferrocene (1), (Z)-octadecen-9-ylferrocene (2), and ferrocenylmethyl (Z)-octadec-9-enoate (3)-were studied. At low hydration, the reversed micelles (L-2 phase) and cubic Q(230) phase of MO can accommodate relatively high amounts
In this paper, we present a new way to control linear stochastic systems. The method is based on statistical bootstrap techniques. The optimal future control signal is derived in such a way that unknown noise distribution and uncertainties in parameter estimates are taken into account. This is achieved by resampling from existing data when calculating statistical distributions of future process va
Rotational bands have been found in Co-57 and Ni-57, using Gammasphere in conjunction with the Microball and 30 neutron detectors. The bands in Co-57, extending the mass 60 region of deformation down to Z = 27, are signature partner sequences. The quadrupole moments and dynamic moments of inertia of the new bands in both nuclei are similar to those of rotational sequences in the neighboring nuclei
Aims: In a population of middle-aged women a survey was carried out to ascertain the prevalence of mental symptoms and psychotropic drug use, and further to investigate whether severe mental symptoms are associated with social situation, alcohol consumption, smoking, and physical health. Methods: All women (n510,766) aged 50-59 years and living in the Lund area were invited to the WHILA study, a h
In this paper, two approaches to data mining of time series have been tested and compared. Both methods are based on the wavelet decomposition of data series and allow the localization of important characteristics of a time series in both the time and frequency domain. The first method is a common method based on the analysis of wavelet power spectra. The second approach is new to the applied fiel
We have identified a novel von Willebrand factor/fibrinogen/selectin-independent, platelet adhesion-promoting function of vascular PG-M/versicans that may be relevant in normal venous thrombosis and critical in atherosclerotic conditions. A purification scheme was devised to obtain vascular versicans, which by biochemical, immunochemical, and ultrastructural means were asserted to be 1) composed p
The light response of a BGO crystal has been measured for particles Z = 1-8, A = 1-16 in the energy range similar to2-60 A MeV. The reaction products are identified by a DeltaE(Si) - E(Sci/PD) telescope, The position of the jump in the value of the signal from the PD at the punch-through points is used to calibrate both the DeltaE(Si) and E(Sci/PD) scales in MeV. The dependence of the light output
Cultures for Malassezia yeasts were taken from both normal-looking skin and lesional skin in 124 patients with atopic dermatitis, 16 patients with seborrhoeic dermatitis and from normal skin of 31 healthy controls. Positive Malassezia growth was found in fewer patients with atopic dermatitis (56%) than in patients with seborrhoeic dermatitis (88%) or in healthy controls (84%, p < 0.01). In the pat
The aims of this study were to describe which self-care, productivity, and leisure occupations individuals with multiple sclerosis (MS) perceive as difficult to perform on admission to rehabilitation and the individuals' own perception of the importance of, performance of, and satisfaction with these occupations. Whether the reported self-care, productivity, and leisure occupations were related to
