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Objective: To summarize recent knowledge on the small molecular weight protein cystatin C (cys-C) and its use as a marker of the glomerular filtration rate (GFR). Methods: A multinational expert meeting was held in April 2002 in Marburg, Germany. Contributors summarized their main findings. Conclusions: Cys-C is at least equal if not superior to serum creatinine as a marker of GFR. The independenc
The interaction between living groups A, C and G streptococci and IgG Fc was studied using human IgG, IgG Fc and IgG Fc-intermediate (Fci) fragments, chemically modified human IgG and fragment D of staphylococcal protein A (SPA). Diethylpyrocarbonate modification of His or N-acetylimidazole modification of Tyr of human IgG resulted in the loss of its capacity to inhibit the binding of radiolabelle
Penetrative convection is discussed where the instability is driven by radiative heating of water below the temperature of maximum density. Convection of this type occurs in ice-covered freshwater lakes in late spring, when the snow cover vanishes and solar radiation is absorbed beneath the ice cover. The vertical temperature structure, bulk mixed layer scaling, and mixed layer deepening are exami
Monocarboxylate transporter 8 (MCT8) is a thyroid hormone transporter, the gene of which is located on the X chromosome. We tested whether mutations in MCT8 cause severe psychomotor retardation and high serum triiodothyronine (T,) concentrations in five unrelated young boys. The coding sequence of MCT8 was analysed by PCR and direct sequencing of its six exons. In two patients, gene deletions of 2
The high number of /-expressing T cells found in the epithelial lining layer suggests that they form a first line of defence against invading pathogens. To evaluate the role of / T cell-receptor (TCR)-expressing cells in cutaneous infection caused by Staphylococcus aureus, mice lacking /-expressing T cells (TCR/) were inoculated intradermally with S. aureus, and compared with S. aureus-infected co
BACKGROUND: Asthma guidelines recommend that long-acting inhaled beta-agonists should be used as maintenance therapy for patients with asthma inadequately controlled on an inhaled corticosteroid. We studied the safety and efficacy of the long-acting beta-agonist formoterol compared with terbutaline, each taken as needed, in patients with moderate to severe asthma. METHODS: Patients were taking an
Aim: The aim of this study was to evaluate the patterns of compliance and the frequency of adenomas and neoplasms in a Swedish population. Methods: In 1996, 2000 men and women born in 1935 or 1936 were selected at random from the population registers of Uppsala and Malmo/Lund. All subjects were invited by mail to participate. In a randomised study design, subjects were either called up by a nurse
The modeling of soot formation and oxidation under industrially relevant conditions has made significant progress in recent years. Simplified models introducing a small number of transport equations into a CFD Code have been used with some success in research configurations simulating a reciprocating diesel engine. Soot formation and oxidation in the turbulent flow is calculated on the basis of a
This thesis concerns the law/fact distinction in law. The interest it takes in the distinction is not practical, but conceptual. It more specifically concerns the questions: “What is it that is conceptually assumed about something when it is categorized as ‘of law’ or ‘of fact’?” and “What is conceptually assumed about the law when law is distinguished from fact by the use of the law/fact distinctThis thesis concerns the law/fact distinction in law. The interest it takes in the distinction is not practical, but conceptual. It more specifically concerns the questions: “What is it that is conceptually assumed about something when it is categorized as ‘of law’ or ‘of fact’?” and “What is conceptually assumed about the law when law is distinguished from fact by the use of the law/fact distinct
Evaluation of anti-proliferative effect of BSA-1 and 32/26/2B in Y79 retinoblastoma cancer cells.
This article presents a summary of what has been achieved during the last 20 years within the project 'The hawkweeds (Hieracium s.s.) of Sweden' in general, and concerning Hieracium sect. Vulgata in particular, a review of our present understanding of the taxonomy and evolution of this group, as well as some new results and classifications that will be implemented in a forthcoming monographic trea
Laptops and smartphones are now challenging the traditional boarders of work and have contributed to new ways of combining work and other parts of life. Both time and room dimensions have been resolved or taken new forms through the new information and communication technology. Questions like when and where you are supposed to, or can or want to work are likewise important to companies and employeLaptops and smartphones are now challenging the traditional boarders of work and have contributed to new ways of combining work and other parts of life. Both time and room dimensions have been resolved or taken new forms through the new information and communication technology. Questions like when and where you are supposed to, or can or want to work are likewise important to companies and employe
Agricultural intensification and the subsequent fragmentation of semi-natural habitats severely restrict pollinator and pollen movement threatening both pollinator and plant species. Linear landscape elements such as hedgerows are planted for agricultural and conservation purposes to increase the resource availability and habitat connectivity supporting populations of beneficial organisms such as Agricultural intensification and the subsequent fragmentation of semi-natural habitats severely restrict pollinator and pollen movement threatening both pollinator and plant species. Linear landscape elements such as hedgerows are planted for agricultural and conservation purposes to increase the resource availability and habitat connectivity supporting populations of beneficial organisms such as
Quaternary ammonium (QA) cations with high alkaline stability are crucial for the long term performance of anion-exchange membrane (AEM) fuel cells. Here, we have tethered poly(phenylene oxide) (PPO) with 8 different hetero-cycloaliphatic QA cations via pentyl spacer chains. The thermal and alkaline stability, as well as hydroxide ion conductivity, were systematically evaluated with the primary ai
The assessment of effects of anthropogenic disturbance on biodiversity (BD) and ecosystem services (ES) and their relationships are key priorities of the Intergovernmental Panel for Biodiversity and Ecosystem Services. Agricultural landscapes and their associated BD provide multiple ES and it is crucial to understand how relationships between ES and BD components change along gradients of landscap
We measured methane fluxes of a patterned bog situated in Siikaneva in southern Finland from six different plant community types in three growing seasons (2012-2014) using the static chamber method with chamber exposure of 35 min. A mixed-effects model was applied to quantify the effect of the controlling factors on the methane flux.The plant community types differed from each other in their water
Fluxes of methane, CH4, were measured with the eddy covariance (EC) method at a small boreal lake in Sweden. The mean CH4 flux during the growing season of 2013 was 20.1 nmol m−2 s−1 and the median flux was 16 nmol m−2 s−1 (corresponding to 1.7 mmol m−2 d−1 and 1.4 mmol m−2 d−1). Monthly mean values of CH4 flux measured with the EC method were compared with fluxes measured with floating chambers (
