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Evaluating flow cytometry for investigating slow sand filter function in drinking water treatment

Flödescytometri som verktyg i dricksvattenproduktionens kvalitetssäkrande arbete Dricksvattenproducenter har flera metoder för att undersöka och kontrollera vattnets kvalitet. Den mikrobiella kvaliteten kan ta allt ifrån 18h till sju dygn att fastställa. Flödescytometri är en metod som har föreslagits som ett potentiellt alternativ eller tillägg till dessa metoder, och som erbjuder korta analystiQuality assurance is crucial for producers of drinking water, and several steps are taken to ensure a safe and aesthetically acceptable drinking water. Monitoring the microbiological quality of drinking water, both finished and within the drinking water treatment plants, is done through cultivation-based techniques. These techniques can take up several days before results can be seen, and quicker

Fractionation gives therapeutic benefit in animal model of [177Lu]Lu-PSMA-617 therapy of prostate cancer

BackgroundThe clinical standard practice of [177Lu]Lu-PSMA-617 therapy is a single injection per treatment cycle, with 6 weeks between cycles. While clinical schedules currently utilize single-bolus cycles, splitting a treatment cycle into multiple smaller injections has demonstrated benefits in other radionuclide therapies, preclinically and in clinical studies. Potential mechanisms for improved BackgroundThe clinical standard practice of [177Lu]Lu-PSMA-617 therapy is a single injection per treatment cycle, with 6 weeks between cycles. While clinical schedules currently utilize single-bolus cycles, splitting a treatment cycle into multiple smaller injections has demonstrated benefits in other radionuclide therapies, preclinically and in clinical studies. Potential mechanisms for improved

Interventions for negative symptoms in schizophrenia : efficacy and clinical interpretability in a meta-analysis of 451 randomized controlled trials

Negative symptoms (avolition, anhedonia, asociality, blunted affect, and alogia) are among the most disabling features of schizophrenia spectrum disorders. In the absence of treatment consensus guidelines, this PRISMA-compliant meta-analysis (PROSPERO: CRD42024613967) evaluated efficacy and clinical significance of interventions targeting this dimension. Web of Science/PsycInfo databases were sear

Learning outcomes of infants and young children with spinal muscular atrophy type I provided with modified-electric-toy-cars in their natural environment

Objectives: To examine powered mobility learning in children with spinal muscular atrophy (SMA) type I, involving families and evaluating goal attainment through the use of small, modified electric toy cars in the children’s natural environments. Design: Single-blind pilot intervention study derived from an originally planned wait-list randomized controlled trial. This report includes only the imm

Devalveringen 1982 - rivstart eller snedtändning? : Perspektiv på svensk devalveringspolitik

Under åren 1976 till 1982 devalverades den svenska kronan sammanlagt fem gånger, sista gången 1982 med hela 16 procent. Denna offensiva devalvering var den första åtgärd som den nya socialdemokratiska regeringen vidtog efter valsegern 1982. Superdevalveringen var ett spännande ekonomiskt och politiskt experiment som knappast har någon tidigare motsvarighet i vår växelkurspolitiska historia. Den på

Longitudinal Micronutrient Exposure Reveals Country-Specific Associations with Risk of Celiac Disease in Genetically Susceptible Children: The Prospective TEDDY Cohort: Nutrient Intake and Risk of Celiac Disease

AbstractBackgroundThe role of nutrient intake in celiac disease pathogenesis is poorly understood.ObjectiveTo examine whether longitudinal childhood intake of selected vitamins and minerals is associated with celiac disease autoimmunity (CDA, primary outcome) and celiac disease (secondary outcome) in genetically at-risk children.MethodsA total of 6,520 HLA-conferred at-risk children in the observa

Material consequences : the return of inflation and the value of price indexation

Inflation is not merely a shift in the value of money, it is also involving a redistribution of value. While some groups are severely affected by inflation, others profit from it. So, who bears the costs of inflation: corporations, employees, or consumers? And how is this redistribution taking place, by which devices? This study takes a critical look at a central device used in various markets: th

The Ethical and Legal Complexities of Regulating Companion AI Chatbots

Companion AI chatbots are increasingly used to provide friendship, emotional support, and quasi-romantic relationships, with reported benefits for loneliness and mental health. At the same time, recent suicides and other serious harms allegedly linked to such systems expose gaps in existing ethical and legal frameworks. This article interrogates these gaps through four lenses: anthropomorphism, em

Political Manipulation in the Age of Interactive AI: The Case for Protecting Freedom of Thought under the ECHR

Interactive AI systems - large language models, conversational agents, and chatbots - are rapidly becoming primary interfaces through which citizens access and evaluate political information. Developed and governed largely by private corporations, these systems do not merely distribute content: they shape opinion formation through sustained, adaptive, and personalised dialogue, relocating politica

Security, Affective Computing, and the Protection of the Free Mind

Emotional AI systems decode human emotions through facial micro-expressions, vocal patterns, and physiological data. While the EU Artificial Intelligence Act prohibits emotion recognition in workplaces and educational institutions, broad security exemptions permit deployment in military, defense, national security, and law enforcement contexts. This article demonstrates how these exemptions create

Effects of stabilized hypochlorous acid on oral biofilm bacteria

BACKGROUND: Caries and periodontitis are amongst the most prevalent diseases worldwide, leading to pain and loss of oral function for those affected. Prevention relies heavily on mechanical removal of dental plaque biofilms but for populations where this is not achievable, alternative plaque control methods are required. With concerns over undesirable side-effects and potential bacterial resistanc

A novel multiplex fluorescent-labeling method for the visualization of mixed-species biofilms in vitro

In nature, bacteria usually exist as mixed-species biofilms, where they engage in a range of synergistic and antagonistic interactions that increase their resistance to environmental challenges. Biofilms are a major cause of persistent infections, and dispersal from initial foci can cause new infections at distal sites thus warranting further investigation. Studies of development and spatial inter

Temporal Proteomic Remodeling of Cerebral Arteries in Male Hypertensive Rats

BACKGROUND: Hypertension is a significant risk factor for several neurological disorders, including stroke and dementia, yet the molecular mechanisms underlying these risks remain poorly understood. In this study, we investigated temporal proteomic remodeling of the cerebrovasculature in male spontaneously hypertensive rats and normotensive Wistar-Kyoto controls at 30 and 40 weeks of age, represen

Strong Convergence of a Splitting Method for the Stochastic Complex Ginzburg–Landau Equation

We consider the numerical approximation of the stochastic complex Ginzburg-Landau equation with additive noise on the one-dimensional torus. The complex nature of the equation means that many of the standard approaches developed for stochastic partial differential equations cannot be directly applied. We use an energy approach to prove an existence and uniqueness result as well as to obtain moment

The first single-stranded DNA virus targeting Pectobacterium belongs to the family Microviridae and demonstrates a broad host range to Pectobacterium brasiliense soft rot pathogens

UNLABELLED: Pectobacterium brasiliense ( Pbr) is known to be one of the most virulent Pectobacterium species and is generally widely distributed across the globe, especially known for causing soft rot in potato-tubers and black leg in potato-plants. Currently no treatment mechanism exists, and many studies have focused on alternative treatment approaches such as biocontrol agents. Several studie

InfraVis-The Swedish Research Infrastructure for Visualization Support

Essentially all academic research of today relies on analysis of data from a wide range of sources. Several underpinning, and rapidly developing, technologies are supporting the analysis of this data. Visualization serves as an interface to this ecosystem of tools and methods and integrates them into environments supporting scientific workflows, effectively sharing cognitive load between computers

Structural Constraints, Practical Possibilities: Reflections from a Graduate School in Development Research

This essay reflects on the Development Research School, a research school launched in 2022 by Lund University, Uppsala University, the University of Gothenburg, and the University of Ghana. Using this case, the essay explores two central themes: how research schools can add value to PhD education, and the particular challenges of running such a school in the field of development research. Based on